2-oxoglutarate |
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Name |
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2-oxoglutarate
oxoglutaric acid
2-Ketoglutaric acid
alpha-Ketoglutaric acid
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Formula |
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C5H6O5 |
Classification |
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It's an a-keto acid (molecule formed after the deamination of an amino acid - in this case glutamate) |
Pathways |
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Urea cycle (3D) |
Citrate cycle (3D) |
Gluconeogenesis
(3D) |
Catabolism of proline, histidine, arginine, glutamate and glutamine (steps 1.4.1.2
and 2.6.1.13)
3D (steps
1.4.1.2
and 2.6.1.13) |
Catabolism of tryptophan and lysine (steps 1.5.1.7
and 2.6.1.39)
3D (steps 1.5.1.7
and 2.6.1.39) |
Catabolism of threonine, tryptophan, glycine, proline, arginine, cysteine and
serine (steps 2.6.1.2
and 2.6.1.1)
3D (steps 2.6.1.2
and 2.6.1.1) |
Catabolism of phenylalanine, tyrosine and leucine (steps 2.6.1.42
and 2.6.1.5)
3D (steps 2.6.1.42
and 2.6.1.5) |
Catabolism of isoleucine, leucine and tryptophan (steps 2.6.1.2;
2.6.1.42 Catabolism of isoleucine and 2.6.1.42
Catabolism of leucine)
3D (steps 2.6.1.2;
2.6.1.42 Catabolism of isoleucine and 2.6.1.42
Catabolism of leucine) |
Catabolism of aspartate and asparagine (3D) |
Catabolism of methionine, threonine, isoleucine and valine (3D) |
Synthesis of aspartate, methionine, lysine and threonine (steps 2.6.1.1
and 2.6.1.17)
3D (steps 2.6.1.1
and 2.6.1.17) |
Synthesis of valine, alanine, isoleucine and leucine (steps 2.6.1.42
Catabolism of isoleucine and valine and 2.6.1.42
Catabolism of leucine)
3D (steps 2.6.1.42
Catabolism of isoleucine and valine and 2.6.1.42
Catabolism of leucine) |
Synthesis of phenylalanine and tyrosine (3D) |
Synthesis of serine, glycine and cysteine (3D) |
Synthesis of histidine (3D) |
Synthesis of glutamine, arginine, glutamate and proline (steps 1.4.1.2
and 2.6.1.11)
3D (steps 1.4.1.2
and 2.6.1.11) |
Ascorbate and aldarate metabolism (Kyoto
University) |
Ubiquinone biosynthesis (Kyoto University) |
Glyoxylate and dicarboxylate metabolism (Kyoto
University) |
Butanoate metabolism (Kyoto University) |
C5-Branched dibasic acid metabolism (Kyoto
University) |
Reductive carboxylate cycle (CO2 fixation) (Kyoto
University) |
Vitamin B6 metabolism (Kyoto University) |
Other comments |
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And the transamination reactions:
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