Acetoacetyl-Coa
+
+
4-Fumaryl-acetoacetate
4-Maleyl-acetoacetate
3-methyl-glutaconyl-CoA
Homogentisate
Isovaleryl-CoA
glucocorticoids
2-oxoisovalerate,
2-oxo-3-methyl-valerate
2-Oxoisocaproate
Overview:
L-Phenylalanine
+ 2-oxoglutarate +3O2 +NADH ---> Acetyl-CoA +Glutamate+NAD+
+CO2 +H2O
L-Tyrosine + 2-oxoglutarate +2O2 ---> Acetyl-CoA +Glutamate +H+ +CO2
Leucina + 2-oxoglutarate + NAD+ + FAD + ATP + 2H2O ---> 2 Acetyl-CoA +Glutamate + NADH + FADH2 + ADP + Pi
L-Tyrosine + 2-oxoglutarate +2O2 ---> Acetyl-CoA +Glutamate +H+ +CO2
Leucina + 2-oxoglutarate + NAD+ + FAD + ATP + 2H2O ---> 2 Acetyl-CoA +Glutamate + NADH + FADH2 + ADP + Pi
Amino acids
catabolism
Phenylalanine, tyrosine and Leucine
to Acetyl-CoA
Phenylalanine, tyrosine and Leucine
to Acetyl-CoA
3-(methylene-)
cyclopropylalanine