Enzyme - EC 2.6.1.42 - Branched-chain amino acid aminotransferase
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EC
2.6.1.42
Official Name
Branched-chain amino acid aminotransferase
Alternative Name(s)
Transaminase B
Class
2.Transferases
6.Transferring nitrogenous groups
1.Transaminases
6.Transferring nitrogenous groups
1.Transaminases
Catalysed reaction
L-leucine + 2-oxoglutarate
4-methyl-a-oxopentanoate
+ L-glutamate
4-methyl-a-oxopentanoate
+ L-glutamateSubstrates
L-leucine
L-isoleucine
L-valine
2-oxoglutarate
L-isoleucine
L-valine
2-oxoglutarate
Products
4-methyl-a-oxopentanoate
L-glutamate
3-methyl-a-oxopentanoate
3-methyl-a-oxopentanoate
L-glutamate
3-methyl-a-oxopentanoate
3-methyl-a-oxopentanoate
Cofactor(s)
Pyridoxal-P
Metabolic Pathways
Synthesis of alanine leucine, isoleucine and valine (3D)
Catabolism of leucine, isoleucine and tryptophan (3D - leucine andisoleucine)
Catabolism of methionine, threonine, isoleucine and valine (3D)
Pantothenate and CoA biosynthesis (Kyoto University)
Catabolism of leucine, isoleucine and tryptophan (3D - leucine andisoleucine)
Catabolism of methionine, threonine, isoleucine and valine (3D)
Pantothenate and CoA biosynthesis (Kyoto University)
Other comments
Also acts on L-isoleucine and L-valine.