Proline, hystidine, arginine, glutamate and glutamine oxidation

Links

Degradation pathways :

histidine ammonia-lyase

cysteine

Arginine

urocanate hydratase

high protein diet

ornithine, lysine, citrate, creatine, guanidino-acetate

4-Imidazolone-5-propanoate

Acceptor

proline dehydrogenase

reduced acceptor

imidazolonepropionase

ornithine-oxo-acid transaminase

ornithine, valine

L-1-Pyrroline-5-carboxylate

N-Formimino-L-glutamate

L-Glutamate 5-semialdehyde

non-enzimatic

H₄folate

glutamate formimidoyltransferase

NAD+/NADP+, H₂O

1-pyrroline-5-carboxylate dehydrogenase

NADH/NADPH + H⁺

5-Formiminotetrahydrofolate

+

Pi

NADP+, H₂O

glutamate dehydrogenase

ADP, ATP

GTP, GDP, ITP, IDP, estradiol, diethyl-b-estrol, testosterone

NADPH + H⁺, NH₄⁺

Arginine

Proline

Histidine Glutamate Glutamine

2-oxoglutarato

Amino acids catabolism
Proline, Histidine, Arginine, Glutamate and Glutamine
to 2-oxoglutarate

Overview:

NH₄⁺

or by enzyme 6.3.1.2 - see glutamine synthesis

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