Enzyme - EC
1.5.1.12 - 1-pyrroline-5-carboxylate dehydrogenase
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The tridimensional structure
of this enzyme has not been resolved yet.
EC
1.5.1.12
Official
Name
1-pyrroline-5-carboxylate dehydrogenase
Alternative
name(s)
--
Class
1.Oxidoreductases
5.Acting on the CH-NH group of donors
1.With NAD+ or NADP+ as acceptor
5.Acting on the CH-NH group of donors
1.With NAD+ or NADP+ as acceptor
Reaction
catalysed
1-pirroline-5-carboxylate
+ NAD+ + H2O 
L-glutamate
+ NADH
L-glutamate
+ NADHSubstrates
1-pirroline-5-carboxylate
NAD+
H2O
L-1-pirroline-3-hydroxy-5-carboxylate
NAD+
H2O
L-1-pirroline-3-hydroxy-5-carboxylate
Products
L-glutamate
NADH
4-hydroxy-L-glutamate
NADH
4-hydroxy-L-glutamate
Metabolic Pathways
Other
comments
Oxidizes other 1-pyrrolines, e.g. 3-hydroxy-1-pyrroline-5- carboxylate forms 4-hydroxyglutamate.
Belongs to the aldehyde dehydrogenases family.