Enzyme - EC 1.14.13.9 - Kynurenine 3-monooxygenase
 

The tridimensional structure of this enzyme has not been resolved yet.
EC
  
1.14.13.9
Official Name
  
Kynurenine 3-monooxygenase
Alternative name(s)
 
Kynurenine 3-hydroxylase
Class
  
1.Oxidoreductases
14.Acting on paired donors with incorporation of molecular oxygen
13.With NADH or NADPH as one donor, and incorporation of one atom of oxygen
Reaction catalysed
  
L-Kynurenine + NADPH + O2 3-Hydroxy-L-Kynurenine + NADP+ H2O
Substrates
  
L-Kynurenine
NADPH
O2
Products
  
3-Hydroxy-L-Kynurenine
NADP+
H2O

Cofactor

  
FAD
Metabolic Pathways
  
Isoleucine, leucine and tryptophan catabolism (3D)
Tryptophan, glycine, alanine, cysteine and alanine catabolism (3D)
Tryptophan and lysine catabolism (3D)
Other comments
  

A flavoprotein (FAD).
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