Enzyme - EC 4.2.1.17 - Enoyl-CoA hydratase
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Dados da estrutura
Unidade biológica: homohexâmero
EC
4.2.1.17
Official Name
Enoyl-CoA hydratase
Alternative Name(s)
Enoyl hydrase
Unsaturated acyl-CoA hydratase
Unsaturated acyl-CoA hydratase
Class
4.Lyases
2.Carbon-oxygen lyases
1.Hydro-lyases
2.Carbon-oxygen lyases
1.Hydro-lyases
Catalysed reaction
(3S)-3-hydroxyacyl-CoA 
trans-2(ou
3)-enoyl-CoA + H2O
trans-2(ou
3)-enoyl-CoA + H2OSubstrates
(3S)-3-hydroxyacyl-CoA
(3R)-3-hydroxyacyl-CoA
2-methylprop-2-enoyl-CoA
2-methylbut-2-enoyl-CoA
3-methylbut-2-enoyl-CoA
(3R)-3-hydroxyacyl-CoA
2-methylprop-2-enoyl-CoA
2-methylbut-2-enoyl-CoA
3-methylbut-2-enoyl-CoA
Products
cis-2,3-Dehydroacyl-CoA
H2O
3-Hydroxy-2-methylpropanoyl-CoA
(2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA
trans-3-Methylglutaconyl-CoA
Metabolic Pathways
b-oxidation
(3D)
Catabolism of isoleucine, leucine and tryptophan (3D - isoleucine and tryptophan)
Catabolism of tryptophan and lysine (3D)
beta-Alanine metabolism (Kyoto University)
Benzoate degradation (Kyoto University)
Propanoate metabolism (Kyoto University)
Butanoate metabolism (Kyoto University)
Catabolism of isoleucine, leucine and tryptophan (3D - isoleucine and tryptophan)
Catabolism of tryptophan and lysine (3D)
beta-Alanine metabolism (Kyoto University)
Benzoate degradation (Kyoto University)
Propanoate metabolism (Kyoto University)
Butanoate metabolism (Kyoto University)
Other comments
Acts in the reverse direction. With cis-compounds, yields (3R)-3-hydroxyacyl-CoA.