Saturated fatty acid oxidation

Links

Palmitoyl-CoA (16:0)

acyl-CoA dehydrogenase

trans-Hexadec-2-enoyl-CoA (16:1tD2)

enoyl-CoA hydratase

(S)-3-Hydroxyhexadecanoyl-CoA

3-hydroxyacyl-CoA dehydrogenase

NADH

3-Oxopalmitoyl-CoA

acetyl-CoA-acyltransferase

Acetyl-CoA

Miristoyl-CoA (14:0)

acyl-CoA dehydrogenase

trans-Tetradec-2-enoyl-CoA (14:1tD2)

enoyl-CoA hydratase

(S)-3-Hydroxytetradecanoyl-CoA

3-hydroxyacyl-CoA dehydrogenase

3-Oxotetradecanoyl-CoA

acetyl-CoA acyltransferase

Lauroyl-CoA (12:0)

acyl-CoA dehydrogenase

trans-Dodec-2-enoyl-CoA(12:1tD2)

enoyl-CoA hydratase

(S)-3-Hydroxydodecanoyl-CoA

3-hydroxyacyl-CoA dehydrogenase

3-Oxododecanoyl-CoA

acetyl-CoA acyltransferase

Caproyl-CoA (10:0)

acyl-CoA dehydrogenase

trans-Dec-2-enoyl-CoA(10:1tD2)

enoyl-CoA hydratase

(S)-Hydroxydecanoyl-CoA

3-hydroxyacyl-CoA dehydrogenase

3-Oxodecanoyl-CoA

acetyl-CoA acyltransferase

Capriloyl-CoA (8:0)

acyl-CoA dehydrogenase

trans-Oct-2-enoyl-CoA (8:1tD2)

enoyl-CoA hydratase

(S)-3-Hydroxyoctanoyl-CoA

3-hydroxyacyl-CoA dehydrogenase

3-Oxooctanoyl-CoA

acetyl-CoA acyltransferase

Hexanoyl-CoA (6:0)

acyl-CoA dehydrogenase

trans-Hex-2-enoyl-CoA (6:1tD2)

enoyl-CoA hydratase

(S)-3-Hydroxyhexanoyl-CoA

3-hydroxyacyl-CoA dehydrogenase

3-Oxohexanoyl-CoA

acetyl-CoA acyltransferase

Butanoyl-CoA (4:0)

acyl-CoA dehydrogenase

trans-But-2-enoyl-CoA (4:1tD2)

enoyl-CoA hydratase

(S)-3-Hydroxybutyryl-CoA

3-hydroxyacyl-CoA dehydrogenase

acetoacetyl-CoA

acetyl-CoA acyltransferase

2

Fatty acid + ATP + CoA---> Acyl-CoA + PPi + AMP + H⁺

Overview:

Lipids Metabolism
Fatty acids b-oxidation

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