Pentoses cycle

Links

Carbohydrate Metabolism

Pentose-P Pathway

Phase I - hexose to pentose conversion

a-D-glucose-6-P

glucose-6-P dehydrogenase

D-glucosamine-6-P, Acyl-CoA, NADPH

NADPH + H⁺

6-P-D-glucono-1,5-lactone

6-P-gluconolactonase

6-P-D-gluconate

6-P-gluconate dehydrogenase

NADPH + H⁺

3-oxo-6-P-D-gliconate

Phase II - Carbon distribution

glyceraldehyde-3-P

D-Sedoheptulose-7-P

Glyceraldehyde-3-P

Notice the carbon distribution: 5C + 5C

3C + 7C

6C + 4C

ribulose-3-P-epimerase

ribose-5p-epimerase

6-P-gliconate dehydrogenase (same step)

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