Pyrimidine oxidation

Links

Oxidation pathway:

TMP (Thymidine 5'-P)

UMP (Uridine 5'-P)

CMP (Cytidine Mono-P)

cell division, dTDP

dTTP, 5Br-Deoxyuridine

CTP, UTP

5'-nucleotidase

CTP, UTP

Uridine

cytosine deaminase

deoxyribose-5-P

thymidine phosphorylase

deoxy-Ribose-1-P

Thymine

Uracil

dihydropyrimidine dehydrogenase (NADP)

dihydro-thymine

dihydropyrimidinase

3-ureidoisobutyrate

3-ureidopropanoate

b- ureidopropionase

NH₄⁺ + CO₂

3-aminoisobutyrate

Alanine

b-aminoisobutyrate-pyruvate aminotransferase

Methylmalonate semialdehyde

valine catabolism pathway

General metabolism:

Pyrimidines Oxidation

uridine phosphorylase

pyrimidine nucleoside phosphorylase

or by nucleosidase, that uses H₂O and yields non-phosphated ribose

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