Enzyme - EC 6.4.1.3 - Propionyl-CoA carboxylase
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The tridimensional structure of this enzyme has not been resolved yet.
EC
6.4.1.3
Official Name
Propionyl-CoA carboxylase
Alternative Name(s)
PCCase
Class
6.Ligases
4.Forming carbon-carbon bonds
4.Forming carbon-carbon bonds
Catalysed reaction
ATP + propanoyl-CoA + HCO3-
ADP
+ P + (S)-methylmalonil-CoA
ADP
+ P + (S)-methylmalonil-CoASubstrates
ATP
Propanoyl-CoA
Butanoyl-CoA
HCO3-
Propanoyl-CoA
Butanoyl-CoA
HCO3-
Products
ortho-P
(S)-methylmalonyl-CoA
Cofactor(s)
Biotin
Metabolic Pathways
Other comments
Also carboxylates butanoyl-CoA and catalyzes transcarboxylation.
Contains a carbamoyl-P sintase domain.