Site for biochemistry learning, dedicated to professors and students. Didactic material for teaching and studying biochemistry. Metabolic pathways, information about enzymes and other biomolecules. Practice protocols, quizzes, themes for discussion.
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Palmitoyl-Coa
Serine
serine palmitoyltransferase
CoA-SH
,
CO
2
3-dehydro-sphinganine
NADPH
+
H
+
3-dehydrosphinganine reductase
NADP+
Sphinganine
acyl-CoA
sphingosine acetyl transferase
CoA-SH
N-acylsphingosine glucosyltransferase
Ceramide
Sphingomyelin
Glucosylceramide
Steps (from Palmitoyl-CoA and Serine):
1.
Amine syntehsis
2.
Amide linkage of an fatty acid (yielding a ceramide)
3.
Esfinganine dessaturation
4.
Head linkage
Sphingolipids synthesis
FAD
FADH
2
Sphingosine
CDP-choline
CMP
ceramide choline phosphotransferase
UDP-glucose
UDP
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