Enzyme - EC 2.4.1.80 - Ceramide glucosyltransferase
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The tridimensional structure of this enzyme has not been resolved yet.
EC
2.4.1.80
Official Name
Ceramide glucosyltransferase
Alternative Name(s)
Glucosylceramide synthase
UDP glucose-ceramide glucosyltransferase
UDP glucose-ceramide glucosyltransferase
Class
2.Transferases
4.Glycosyltransferases
1.Hexosyltransferases
4.Glycosyltransferases
1.Hexosyltransferases
Catalysed reaction
UDP-glucose + N-acylsphingosine 
UDP
+ D-glucosyl-N-acylsphingosine
UDP
+ D-glucosyl-N-acylsphingosineSubstrates
UDP-glucose
N-acylsphingosine
sphingosine
dihydrosphingosine
CDP-glucose
N-acylsphingosine
sphingosine
dihydrosphingosine
CDP-glucose
Products
UDP
D-glucosyl-N-acylsphingosine
D-glucosylsphingosine
D-glucosyldihydrosphingosine
CDP
D-glucosyl-N-acylsphingosine
D-glucosylsphingosine
D-glucosyldihydrosphingosine
CDP
Metabolic Pathways
Other comments
Sphingosine and dihydrosphingosine can also act as acceptors; CDPglucose can act as donor.