Enzyme - EC 6.4.1.1 - Pyruvate carboxylase

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Dados da estrutura
Unidade biológica - homotetrâmero

EC
 
6.4.1.1
Official Name
Pyruvate carboxylase
Alternative Name(s)
Pyruvic carboxylase
Class
6.Ligases
4.Forming carbon-carbon bonds
Catalysed reaction
ATP + pyruvate + HCO3- ADP + P + oxaloacetate
Substrates
ATP
pyruvate
HCO3-
Products
ADP
ortho-P
oxaloacetate
Cofactor(s)
Biotin; Manganese (animal tissues) or Zinc (yeast)
Metabolic Pathways
Other comments

The animal enzyme requires acetyl-CoA.

Contains a carbamoyl-P sintase domain.

Biotin-requiring enzyme.


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