Enzyme - EC 3.5.4.6 - AMP deaminase
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The tridimensional structure of this enzyme has not been resolved yet.
EC
3.5.4.6
Official Name
AMP deaminase
Alternative Name(s)
Myoadenylate deaminase
AMP aminase
Adenylic acid deaminase
Adenylate deaminase
5-AMP deaminase
AMP aminohydrolase
AMP aminase
Adenylic acid deaminase
Adenylate deaminase
5-AMP deaminase
AMP aminohydrolase
Class
3.Hydrolases
5.Acting on carbon-nitrogen bonds, other than peptide bonds
4.In cyclic amidines
5.Acting on carbon-nitrogen bonds, other than peptide bonds
4.In cyclic amidines
Catalysed reaction
AMP + H2O 
IMP
+ NH3
IMP
+ NH3Substrates
AMP
H2O
H2O
Products
NH3
Metabolic Pathways
Other comments
Adenosine
deaminase (EC 3.5.4.4) catalyzes the hydrolytic deamination of
adenosine into inosine. AMP deaminase (EC 3.5.4.6) catalyzes the hydrolytic
deamination of AMP into IMP. It has been shown that these two types of
enzymes share three regions of sequence similarities; these regions are
centered on residues which are proposed to play an important role in the
catalytic mechanism of these two enzymes. We have selected one of these
regions, it contains two conserved aspartic acid residues that are potential
active site residues.
Reference