Enzyme - EC
1.1.1.1 Alcohol dehydrogenase
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EC
1.1.1.1
Official
Name
Alcohol dehydrogenase
Alternative
name(s)
aldehyde reductase
Class
1.Oxidoreductases
1.Acting on the CH-OH group of donors
1.With NAD+ or NADP+ as acceptor
1.Acting on the CH-OH group of donors
1.With NAD+ or NADP+ as acceptor
Reaction
Alcohol + NAD+
aldehyde
or ketone + NADH + H+
aldehyde
or ketone + NADH + H+Substrates
NAD+
Primary alcohol
Secondary alcohol
Cyclic secondary alcohol
Hemiacetal
Primary alcohol
Secondary alcohol
Cyclic secondary alcohol
Hemiacetal
Products
aldehyde
Ketone
NADH
Ketone
NADH
Cofactors
Zinc or Iron
Metabolic Pathways
Other
comments
It's a zinc protein that acts on primary or secondary alcohols or hemiacetals. The animal enzyme (but not the yeasts' one) acts also on cyclic secondary alcohols.
Currently three, structurally and catalytically, different types of alcohol dehydrogenases are known: zinc-containing long chain; short chain and (insect-type; iron-containing alcohol dehydrogenases.