HEADER ISOMERASE 08-DEC-00 1HNU TITLE CRYSTAL STRUCTURE OF PEROXISOMAL DELTA3-DELTA2-ENOYL-COA TITLE 2 ISOMERASE FROM SACCHAROMYCES CEREVISIAE COMPND MOL_ID: 1; COMPND 2 MOLECULE: D3,D2-ENOYL COA ISOMERASE ECI1; COMPND 3 CHAIN: A; COMPND 4 EC: 5.3.3.8; COMPND 5 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE; SOURCE 3 ORGANISM_COMMON: YEAST; SOURCE 4 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 5 EXPRESSION_SYSTEM_COMMON: BACTERIA; SOURCE 6 EXPRESSION_SYSTEM_STRAIN: BL21(DE3)PLYSS; SOURCE 7 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 8 EXPRESSION_SYSTEM_PLASMID: PET3A KEYWDS ALPHA/BETA EXPDTA X-RAY DIFFRACTION AUTHOR A.M.MURSULA,D.M.F.VAN AALTEN,J.K.HILTUNEN,R.K.WIERENGA REVDAT 2 05-SEP-01 1HNU 3 ATOM SEQRES SEQADV REVDAT 1 20-JUN-01 1HNU 0 JRNL AUTH A.M.MURSULA,D.M.F.VAN AALTEN,J.K.HILTUNEN, JRNL AUTH 2 R.K.WIERENGA JRNL TITL THE CRYSTAL STRUCTURE OF DELTA3-DELTA2-ENOYL-COA JRNL TITL 2 ISOMERASE JRNL REF J.MOL.BIOL. V. 309 845 2001 JRNL REFN ASTM JMOBAK UK ISSN 0022-2836 REMARK 1 REMARK 1 REFERENCE 1 REMARK 1 AUTH A.M.MURSULA,D.M.VAN AALTEN,Y.MODIS,J.K.HILTUNEN, REMARK 1 AUTH 2 R.K.WIERENGA REMARK 1 TITL CRYSTALLIZATION AND X-RAY DIFFRACTION ANALYSIS OF REMARK 1 TITL 2 PEROXISOMAL DELTA3-DELTA2-ENOYL-COA ISOMERASE FROM REMARK 1 TITL 3 SACCHAROMYCES CEREVISIAE REMARK 1 REF ACTA CRYSTALLOGR., SECT.D V. 56 1020 2000 REMARK 1 REFN ASTM ABCRE6 DK ISSN 0907-4449 REMARK 2 REMARK 2 RESOLUTION. 2.15 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : REFMAC REMARK 3 AUTHORS : MURSHUDOV,VAGIN,DODSON REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 2.15 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 20.0 REMARK 3 DATA CUTOFF (SIGMA(F)) : 0.000 REMARK 3 COMPLETENESS FOR RANGE (%) : NULL REMARK 3 NUMBER OF REFLECTIONS : 26907 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 CROSS-VALIDATION METHOD : NULL REMARK 3 FREE R VALUE TEST SET SELECTION : RANDOM REMARK 3 R VALUE (WORKING + TEST SET) : 0.215 REMARK 3 R VALUE (WORKING SET) : 0.215 REMARK 3 FREE R VALUE : 0.257 REMARK 3 FREE R VALUE TEST SET SIZE (%) : NULL REMARK 3 FREE R VALUE TEST SET COUNT : 1347 REMARK 3 REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT. REMARK 3 PROTEIN ATOMS : 1986 REMARK 3 NUCLEIC ACID ATOMS : 0 REMARK 3 HETEROGEN ATOMS : 18 REMARK 3 SOLVENT ATOMS : 194 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : 40.97 REMARK 3 MEAN B VALUE (OVERALL, A**2) : 44.95 REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : NULL REMARK 3 B22 (A**2) : NULL REMARK 3 B33 (A**2) : NULL REMARK 3 B12 (A**2) : NULL REMARK 3 B13 (A**2) : NULL REMARK 3 B23 (A**2) : NULL REMARK 3 REMARK 3 ESTIMATED OVERALL COORDINATE ERROR. REMARK 3 ESU BASED ON R VALUE (A): NULL REMARK 3 ESU BASED ON FREE R VALUE (A): NULL REMARK 3 ESU BASED ON MAXIMUM LIKELIHOOD (A): NULL REMARK 3 ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): NULL REMARK 3 REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES. REMARK 3 DISTANCE RESTRAINTS. RMS SIGMA REMARK 3 BOND LENGTH (A) : 0.018 ; NULL REMARK 3 ANGLE DISTANCE (A) : NULL ; NULL REMARK 3 INTRAPLANAR 1-4 DISTANCE (A) : NULL ; NULL REMARK 3 H-BOND OR METAL COORDINATION (A) : NULL ; NULL REMARK 3 REMARK 3 PLANE RESTRAINT (A) : NULL ; NULL REMARK 3 CHIRAL-CENTER RESTRAINT (A**3) : NULL ; NULL REMARK 3 REMARK 3 NON-BONDED CONTACT RESTRAINTS. REMARK 3 SINGLE TORSION (A) : NULL ; NULL REMARK 3 MULTIPLE TORSION (A) : NULL ; NULL REMARK 3 H-BOND (X...Y) (A) : NULL ; NULL REMARK 3 H-BOND (X-H...Y) (A) : NULL ; NULL REMARK 3 REMARK 3 CONFORMATIONAL TORSION ANGLE RESTRAINTS. REMARK 3 SPECIFIED (DEGREES) : NULL ; NULL REMARK 3 PLANAR (DEGREES) : NULL ; NULL REMARK 3 STAGGERED (DEGREES) : NULL ; NULL REMARK 3 TRANSVERSE (DEGREES) : NULL ; NULL REMARK 3 REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. RMS SIGMA REMARK 3 MAIN-CHAIN BOND (A**2) : 4.182 ; NULL REMARK 3 MAIN-CHAIN ANGLE (A**2) : NULL ; NULL REMARK 3 SIDE-CHAIN BOND (A**2) : NULL ; NULL REMARK 3 SIDE-CHAIN ANGLE (A**2) : NULL ; NULL REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: NULL REMARK 4 REMARK 4 1HNU COMPLIES WITH FORMAT V. 2.3, 09-JULY-1998 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 13-DEC-2000. REMARK 100 THE RCSB ID CODE IS RCSB012469. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 26-NOV-1999 REMARK 200 TEMPERATURE (KELVIN) : 100.0 REMARK 200 PH : 5.60 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : EMBL/DESY, HAMBURG REMARK 200 BEAMLINE : BW7A REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 1.1765, 1.1773, 1.1697, REMARK 200 1.1836 REMARK 200 MONOCHROMATOR : SYNCHROTRON REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : CCD REMARK 200 DETECTOR MANUFACTURER : MARRESEARCH REMARK 200 INTENSITY-INTEGRATION SOFTWARE : DENZO REMARK 200 DATA SCALING SOFTWARE : SCALEPACK REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 27191 REMARK 200 RESOLUTION RANGE HIGH (A) : 2.150 REMARK 200 RESOLUTION RANGE LOW (A) : 30.000 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : -3.000 REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 99.5 REMARK 200 DATA REDUNDANCY : 4.800 REMARK 200 R MERGE (I) : 0.05300 REMARK 200 R SYM (I) : NULL REMARK 200 FOR THE DATA SET : 16.0000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 2.15 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 2.23 REMARK 200 COMPLETENESS FOR SHELL (%) : 99.7 REMARK 200 DATA REDUNDANCY IN SHELL : 4.80 REMARK 200 R MERGE FOR SHELL (I) : 0.47400 REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200 FOR SHELL : 2.900 REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: MAD REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MAD REMARK 200 SOFTWARE USED: MLPHARE REMARK 200 STARTING MODEL: NULL REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): NULL REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): NULL REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: MES, AMMONIUM SULFATE, 1,4- REMARK 280 DIOXANE REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 63 2 2 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 X-Y,X,1/2+Z REMARK 290 3555 -Y,X-Y,Z REMARK 290 4555 -X,-Y,1/2+Z REMARK 290 5555 -X+Y,-X,Z REMARK 290 6555 Y,-X+Y,1/2+Z REMARK 290 7555 X-Y,-Y,-Z REMARK 290 8555 -Y,-X,1/2-Z REMARK 290 9555 -X,-X+Y,-Z REMARK 290 10555 -X+Y,Y,1/2-Z REMARK 290 11555 Y,X,-Z REMARK 290 12555 X,X-Y,1/2-Z REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 0.500000 -0.866025 0.000000 0.00000 REMARK 290 SMTRY2 2 0.866025 0.500000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 61.63800 REMARK 290 SMTRY1 3 -0.500000 -0.866025 0.000000 0.00000 REMARK 290 SMTRY2 3 0.866025 -0.500000 0.000000 0.00000 REMARK 290 SMTRY3 3 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 4 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 4 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 4 0.000000 0.000000 1.000000 61.63800 REMARK 290 SMTRY1 5 -0.500000 0.866025 0.000000 0.00000 REMARK 290 SMTRY2 5 -0.866025 -0.500000 0.000000 0.00000 REMARK 290 SMTRY3 5 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 6 0.500000 0.866025 0.000000 0.00000 REMARK 290 SMTRY2 6 -0.866025 0.500000 0.000000 0.00000 REMARK 290 SMTRY3 6 0.000000 0.000000 1.000000 61.63800 REMARK 290 SMTRY1 7 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 7 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 7 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 8 0.500000 -0.866025 0.000000 0.00000 REMARK 290 SMTRY2 8 -0.866025 -0.500000 0.000000 0.00000 REMARK 290 SMTRY3 8 0.000000 0.000000 -1.000000 61.63800 REMARK 290 SMTRY1 9 -0.500000 -0.866025 0.000000 0.00000 REMARK 290 SMTRY2 9 -0.866025 0.500000 0.000000 0.00000 REMARK 290 SMTRY3 9 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 10 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 10 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 10 0.000000 0.000000 -1.000000 61.63800 REMARK 290 SMTRY1 11 -0.500000 0.866025 0.000000 0.00000 REMARK 290 SMTRY2 11 0.866025 0.500000 0.000000 0.00000 REMARK 290 SMTRY3 11 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 12 0.500000 0.866025 0.000000 0.00000 REMARK 290 SMTRY2 12 0.866025 -0.500000 0.000000 0.00000 REMARK 290 SMTRY3 12 0.000000 0.000000 -1.000000 61.63800 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 THIS ENTRY CONTAINS THE CRYSTALLOGRAPHIC ASYMMETRIC UNIT REMARK 300 WHICH CONSISTS OF 1 CHAIN(S). SEE REMARK 350 FOR REMARK 300 INFORMATION ON GENERATING THE BIOLOGICAL MOLECULE(S). REMARK 350 REMARK 350 GENERATING THE BIOMOLECULE REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 APPLY THE FOLLOWING TO CHAINS: A REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 350 BIOMT1 2 -0.500000 -0.866025 0.000000 116.13900 REMARK 350 BIOMT2 2 0.866025 -0.500000 0.000000 0.00000 REMARK 350 BIOMT3 2 0.000000 0.000000 1.000000 0.00000 REMARK 350 BIOMT1 3 -0.500000 0.866025 0.000000 58.06950 REMARK 350 BIOMT2 3 -0.866025 -0.500000 0.000000 100.57932 REMARK 350 BIOMT3 3 0.000000 0.000000 1.000000 0.00000 REMARK 350 BIOMT1 4 0.500000 -0.866025 0.000000 58.06950 REMARK 350 BIOMT2 4 -0.866025 -0.500000 0.000000 100.57932 REMARK 350 BIOMT3 4 0.000000 0.000000 -1.000000 61.63800 REMARK 350 BIOMT1 5 -1.000000 0.000000 0.000000 116.13900 REMARK 350 BIOMT2 5 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 5 0.000000 0.000000 -1.000000 61.63800 REMARK 350 BIOMT1 6 0.500000 0.866025 0.000000 0.00000 REMARK 350 BIOMT2 6 0.866025 -0.500000 0.000000 0.00000 REMARK 350 BIOMT3 6 0.000000 0.000000 -1.000000 61.63800 REMARK 375 REMARK 375 SPECIAL POSITION REMARK 375 THE FOLLOWING ATOMS ARE FOUND TO BE WITHIN 0.15 ANGSTROMS REMARK 375 OF A SYMMETRY RELATED ATOM AND ARE ASSUMED TO BE ON SPECIAL REMARK 375 POSITIONS. REMARK 375 REMARK 375 ATOM RES CSSEQI REMARK 375 HOH 105 LIES ON A SPECIAL POSITION. REMARK 375 HOH 225 LIES ON A SPECIAL POSITION. REMARK 375 HOH 424 LIES ON A SPECIAL POSITION. REMARK 375 HOH 430 LIES ON A SPECIAL POSITION. REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 MET A 1 REMARK 465 SER A 2 REMARK 465 GLN A 3 REMARK 465 GLU A 4 REMARK 465 ILE A 5 REMARK 465 ARG A 6 REMARK 465 GLN A 7 REMARK 465 GLY A 74 REMARK 465 ILE A 75 REMARK 465 ALA A 76 REMARK 465 LYS A 77 REMARK 465 ALA A 78 REMARK 465 GLN A 79 REMARK 465 GLY A 80 REMARK 465 ASP A 81 REMARK 465 ASP A 82 REMARK 465 THR A 83 REMARK 465 ASN A 84 REMARK 465 LYS A 85 REMARK 465 TYR A 86 REMARK 465 PRO A 87 REMARK 465 SER A 88 REMARK 465 LEU A 271 REMARK 465 GLY A 272 REMARK 465 SER A 273 REMARK 465 LYS A 274 REMARK 465 GLN A 275 REMARK 465 ARG A 276 REMARK 465 LYS A 277 REMARK 465 HIS A 278 REMARK 465 ARG A 279 REMARK 465 LEU A 280 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT REMARK 500 REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT. REMARK 500 REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI REMARK 500 O12 REO 502 O HOH 390 1.97 REMARK 500 N GLY A 193 O HOH 34 2.08 REMARK 500 O HOH 225 O HOH 350 2.14 REMARK 500 CA GLY A 193 O HOH 34 2.17 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CLOSE CONTACTS REMARK 500 REMARK 500 THE FOLLOWING ATOMS THAT ARE RELATED BY CRYSTALLOGRAPHIC REMARK 500 SYMMETRY ARE IN CLOSE CONTACT. AN ATOM LOCATED WITHIN 0.15 REMARK 500 ANGSTROMS OF A SYMMETRY RELATED ATOM IS ASSUMED TO BE ON A REMARK 500 SPECIAL POSITION AND IS, THEREFORE, LISTED IN REMARK 375 REMARK 500 INSTEAD OF REMARK 500. ATOMS WITH NON-BLANK ALTERNATE REMARK 500 LOCATION INDICATORS ARE NOT INCLUDED IN THE CALCULATIONS. REMARK 500 REMARK 500 DISTANCE CUTOFF: REMARK 500 2.2 ANGSTROMS FOR CONTACTS NOT INVOLVING HYDROGEN ATOMS REMARK 500 1.6 ANGSTROMS FOR CONTACTS INVOLVING HYDROGEN ATOMS REMARK 500 REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI SSYMOP DISTANCE REMARK 500 OE2 GLU A 254 O HOH 406 5665 2.00 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES: ENGH AND HUBER, 1991 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 GLU A 36 CA - CB - CG ANGL. DEV. = 18.6 DEGREES REMARK 500 TRP A 93 C - N - CA ANGL. DEV. = 23.1 DEGREES REMARK 525 REMARK 525 SOLVENT REMARK 525 THE FOLLOWING SOLVENT MOLECULES LIE FARTHER THAN EXPECTED REMARK 525 FROM THE PROTEIN OR NUCLEIC ACID MOLECULE AND MAY BE REMARK 525 ASSOCIATED WITH A SYMMETRY RELATED MOLECULE (M=MODEL REMARK 525 NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE REMARK 525 NUMBER; I=INSERTION CODE): REMARK 525 REMARK 525 M RES CSSEQI REMARK 525 0 HOH 268 DISTANCE = 6.52 ANGSTROMS REMARK 525 0 HOH 403 DISTANCE = 5.40 ANGSTROMS REMARK 525 0 HOH 411 DISTANCE = 6.02 ANGSTROMS REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 1HNO RELATED DB: PDB REMARK 900 1HNO IS THE UNLIGANDED STRUCTURE DBREF 1HNU A 1 280 GB 3643265 AAC83700 1 280 SEQADV 1HNU A 25 GB 3643265 25 ENGINEERED SEQRES 1 A 280 MET SER GLN GLU ILE ARG GLN ASN GLU LYS ILE SER TYR SEQRES 2 A 280 ARG ILE GLU GLY PRO PHE PHE ILE ILE HIS LEU ILE ASN SEQRES 3 A 280 PRO ASP ASN LEU ASN ALA LEU GLU GLY GLU ASP TYR ILE SEQRES 4 A 280 TYR LEU GLY GLU LEU LEU GLU LEU ALA ASP ARG ASN ARG SEQRES 5 A 280 ASP VAL TYR PHE THR ILE ILE GLN SER SER GLY ARG PHE SEQRES 6 A 280 PHE SER SER GLY ALA ASP PHE LYS GLY ILE ALA LYS ALA SEQRES 7 A 280 GLN GLY ASP ASP THR ASN LYS TYR PRO SER GLU THR SER SEQRES 8 A 280 LYS TRP VAL SER ASN PHE VAL ALA ARG ASN VAL TYR VAL SEQRES 9 A 280 THR ASP ALA PHE ILE LYS HIS SER LYS VAL LEU ILE CYS SEQRES 10 A 280 CYS LEU ASN GLY PRO ALA ILE GLY LEU SER ALA ALA LEU SEQRES 11 A 280 VAL ALA LEU CYS ASP ILE VAL TYR SER ILE ASN ASP LYS SEQRES 12 A 280 VAL TYR LEU LEU TYR PRO PHE ALA ASN LEU GLY LEU ILE SEQRES 13 A 280 THR GLU GLY GLY THR THR VAL SER LEU PRO LEU LYS PHE SEQRES 14 A 280 GLY THR ASN THR THR TYR GLU CYS LEU MET PHE ASN LYS SEQRES 15 A 280 PRO PHE LYS TYR ASP ILE MET CYS GLU ASN GLY PHE ILE SEQRES 16 A 280 SER LYS ASN PHE ASN MET PRO SER SER ASN ALA GLU ALA SEQRES 17 A 280 PHE ASN ALA LYS VAL LEU GLU GLU LEU ARG GLU LYS VAL SEQRES 18 A 280 LYS GLY LEU TYR LEU PRO SER CYS LEU GLY MET LYS LYS SEQRES 19 A 280 LEU LEU LYS SER ASN HIS ILE ASP ALA PHE ASN LYS ALA SEQRES 20 A 280 ASN SER VAL GLU VAL ASN GLU SER LEU LYS TYR TRP VAL SEQRES 21 A 280 ASP GLY GLU PRO LEU LYS ARG PHE ARG GLN LEU GLY SER SEQRES 22 A 280 LYS GLN ARG LYS HIS ARG LEU HET REO 501 5 HET REO 502 5 HET EDO 601 4 HET EDO 602 4 HETNAM REO PERRHENATE HETNAM EDO 1,2-ETHANEDIOL HETSYN EDO ETHYLENE GLYCOL FORMUL 2 REO 2(O4 RE1) FORMUL 4 EDO 2(C2 H6 O2) FORMUL 6 HOH *194(H2 O1) HELIX 1 1 ASN A 26 LEU A 30 5 5 HELIX 2 2 GLU A 34 ASN A 51 1 18 HELIX 3 3 GLU A 89 LYS A 92 5 4 HELIX 4 4 TRP A 93 HIS A 111 1 19 HELIX 5 5 GLY A 125 LEU A 133 1 9 HELIX 6 6 PRO A 149 LEU A 153 5 5 HELIX 7 7 GLY A 160 GLY A 170 1 11 HELIX 8 8 GLY A 170 PHE A 180 1 11 HELIX 9 9 TYR A 186 ASN A 192 1 7 HELIX 10 10 ASN A 205 LYS A 222 1 18 HELIX 11 11 TYR A 225 ASN A 239 1 15 HELIX 12 12 HIS A 240 GLY A 262 1 23 HELIX 13 13 GLY A 262 ARG A 269 1 8 SHEET 1 A 6 ILE A 11 GLU A 16 0 SHEET 2 A 6 PHE A 19 LEU A 24 -1 O PHE A 19 N GLU A 16 SHEET 3 A 6 PHE A 56 GLN A 60 1 O PHE A 56 N PHE A 20 SHEET 4 A 6 VAL A 114 LEU A 119 1 O VAL A 114 N THR A 57 SHEET 5 A 6 ILE A 136 SER A 139 1 O ILE A 136 N CYS A 117 SHEET 6 A 6 LYS A 197 ASN A 198 1 O LYS A 197 N SER A 139 SHEET 1 B 3 ALA A 123 ILE A 124 0 SHEET 2 B 3 TYR A 145 LEU A 147 1 O TYR A 145 N ALA A 123 SHEET 3 B 3 PHE A 184 LYS A 185 -1 N PHE A 184 O LEU A 146 CRYST1 116.139 116.139 123.276 90.00 90.00 120.00 P 63 2 2 12 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.008610 0.004970 0.000000 0.00000 SCALE2 0.000000 0.009940 0.000000 0.00000 SCALE3 0.000000 0.000000 0.008110 0.00000 ATOM 1 N ASN A 8 36.564 66.342 14.500 1.00 60.71 N ATOM 2 CA ASN A 8 37.673 66.101 13.529 1.00 55.37 C ATOM 3 C ASN A 8 37.228 66.132 12.070 1.00 52.95 C ATOM 4 O ASN A 8 36.385 65.379 11.602 1.00 64.38 O ATOM 5 CB ASN A 8 38.385 64.772 13.830 1.00 56.05 C ATOM 6 CG ASN A 8 39.770 64.748 13.232 1.00 52.58 C ATOM 7 OD1 ASN A 8 39.846 64.711 12.002 1.00 53.32 O ATOM 8 ND2 ASN A 8 40.827 64.778 14.044 1.00 53.32 N ATOM 9 N GLU A 9 37.956 66.869 11.268 1.00 48.95 N ATOM 10 CA GLU A 9 37.712 67.127 9.878 1.00 55.70 C ATOM 11 C GLU A 9 38.586 66.260 8.966 1.00 53.59 C ATOM 12 O GLU A 9 38.311 66.191 7.772 1.00 50.25 O ATOM 13 CB GLU A 9 38.168 68.597 9.586 1.00 57.94 C ATOM 14 CG GLU A 9 37.105 69.650 9.793 1.00 68.37 C ATOM 15 CD GLU A 9 37.549 71.028 9.332 1.00 77.72 C ATOM 16 OE1 GLU A 9 38.747 71.230 9.015 1.00 76.25 O ATOM 17 OE2 GLU A 9 36.700 71.953 9.301 1.00 89.11 O ATOM 18 N LYS A 10 39.628 65.656 9.541 1.00 49.09 N ATOM 19 CA LYS A 10 40.540 64.869 8.704 1.00 46.17 C ATOM 20 C LYS A 10 40.171 63.413 8.702 1.00 41.69 C ATOM 21 O LYS A 10 40.801 62.582 8.023 1.00 43.85 O ATOM 22 CB LYS A 10 41.954 65.070 9.212 1.00 47.67 C ATOM 23 CG LYS A 10 42.458 66.528 9.227 1.00 51.98 C ATOM 24 CD LYS A 10 43.713 66.567 10.082 1.00 48.06 C ATOM 25 CE LYS A 10 44.401 67.938 10.117 1.00 52.47 C ATOM 26 NZ LYS A 10 45.326 67.978 11.309 1.00 50.01 N ATOM 27 N ILE A 11 39.285 63.016 9.617 1.00 40.12 N ATOM 28 CA ILE A 11 38.915 61.628 9.797 1.00 37.25 C ATOM 29 C ILE A 11 37.427 61.487 10.100 1.00 36.23 C ATOM 30 O ILE A 11 36.925 62.064 11.063 1.00 42.67 O ATOM 31 CB ILE A 11 39.710 60.975 10.971 1.00 37.08 C ATOM 32 CG1 ILE A 11 41.244 61.153 10.819 1.00 37.01 C ATOM 33 CG2 ILE A 11 39.384 59.497 11.124 1.00 35.67 C ATOM 34 CD1 ILE A 11 41.956 60.658 12.091 1.00 37.21 C ATOM 35 N SER A 12 36.742 60.612 9.365 1.00 37.26 N ATOM 36 CA SER A 12 35.328 60.335 9.576 1.00 38.00 C ATOM 37 C SER A 12 35.157 58.850 9.878 1.00 39.02 C ATOM 38 O SER A 12 36.086 58.058 9.676 1.00 35.22 O ATOM 39 CB SER A 12 34.514 60.578 8.271 1.00 40.97 C ATOM 40 OG SER A 12 35.052 59.759 7.188 1.00 40.41 O ATOM 41 N TYR A 13 33.928 58.490 10.210 1.00 34.61 N ATOM 42 CA TYR A 13 33.706 57.071 10.466 1.00 38.04 C ATOM 43 C TYR A 13 32.242 56.803 10.274 1.00 39.07 C ATOM 44 O TYR A 13 31.503 57.776 10.447 1.00 39.52 O ATOM 45 CB TYR A 13 34.158 56.683 11.886 1.00 38.71 C ATOM 46 CG TYR A 13 33.294 57.196 13.005 1.00 42.49 C ATOM 47 CD1 TYR A 13 32.271 56.422 13.517 1.00 46.10 C ATOM 48 CD2 TYR A 13 33.444 58.497 13.483 1.00 46.62 C ATOM 49 CE1 TYR A 13 31.444 56.906 14.520 1.00 51.25 C ATOM 50 CE2 TYR A 13 32.645 58.974 14.517 1.00 48.76 C ATOM 51 CZ TYR A 13 31.668 58.175 15.018 1.00 51.03 C ATOM 52 OH TYR A 13 30.860 58.612 16.056 1.00 60.50 O ATOM 53 N ARG A 14 31.908 55.535 10.135 1.00 39.38 N ATOM 54 CA ARG A 14 30.486 55.188 9.998 1.00 44.90 C ATOM 55 C ARG A 14 30.440 53.688 10.266 1.00 48.73 C ATOM 56 O ARG A 14 31.510 53.055 10.158 1.00 39.47 O ATOM 57 CB ARG A 14 29.963 55.443 8.589 1.00 41.09 C ATOM 58 CG ARG A 14 30.607 54.631 7.473 1.00 42.64 C ATOM 59 CD ARG A 14 30.115 55.147 6.090 1.00 43.74 C ATOM 60 NE ARG A 14 30.940 54.643 4.985 1.00 40.04 N ATOM 61 CZ ARG A 14 30.645 53.462 4.443 1.00 44.67 C ATOM 62 NH1 ARG A 14 29.613 52.850 5.011 1.00 44.36 N ATOM 63 NH2 ARG A 14 31.309 52.881 3.480 1.00 47.22 N ATOM 64 N ILE A 15 29.247 53.230 10.543 1.00 38.62 N ATOM 65 CA ILE A 15 29.011 51.819 10.785 1.00 42.49 C ATOM 66 C ILE A 15 28.053 51.300 9.718 1.00 49.26 C ATOM 67 O ILE A 15 27.109 52.037 9.388 1.00 48.87 O ATOM 68 CB ILE A 15 28.396 51.630 12.173 1.00 46.40 C ATOM 69 CG1 ILE A 15 29.296 52.241 13.274 1.00 44.93 C ATOM 70 CG2 ILE A 15 28.042 50.175 12.401 1.00 48.93 C ATOM 71 CD1 ILE A 15 28.879 51.841 14.675 1.00 50.11 C ATOM 72 N GLU A 16 28.303 50.130 9.216 1.00 43.57 N ATOM 73 CA GLU A 16 27.588 49.457 8.135 1.00 52.61 C ATOM 74 C GLU A 16 27.497 47.967 8.462 1.00 51.85 C ATOM 75 O GLU A 16 28.497 47.240 8.349 1.00 53.49 O ATOM 76 CB GLU A 16 28.411 49.769 6.892 1.00 56.61 C ATOM 77 CG GLU A 16 27.780 49.838 5.576 1.00 69.24 C ATOM 78 CD GLU A 16 28.299 50.711 4.488 1.00 72.06 C ATOM 79 OE1 GLU A 16 29.364 50.512 3.846 1.00 71.76 O ATOM 80 OE2 GLU A 16 27.603 51.758 4.247 1.00 78.02 O ATOM 81 N GLY A 17 26.393 47.548 9.066 1.00 48.90 N ATOM 82 CA GLY A 17 26.201 46.172 9.485 1.00 54.53 C ATOM 83 C GLY A 17 27.291 45.887 10.558 1.00 50.13 C ATOM 84 O GLY A 17 27.469 46.735 11.420 1.00 45.99 O ATOM 85 N PRO A 18 28.117 44.875 10.323 1.00 47.70 N ATOM 86 CA PRO A 18 29.130 44.516 11.310 1.00 38.99 C ATOM 87 C PRO A 18 30.432 45.265 11.158 1.00 39.09 C ATOM 88 O PRO A 18 31.403 44.925 11.831 1.00 40.54 O ATOM 89 CB PRO A 18 29.200 42.990 11.068 1.00 38.25 C ATOM 90 CG PRO A 18 29.167 42.915 9.522 1.00 42.44 C ATOM 91 CD PRO A 18 28.016 43.887 9.205 1.00 44.06 C ATOM 92 N PHE A 19 30.579 46.223 10.259 1.00 33.97 N ATOM 93 CA PHE A 19 31.738 46.941 9.886 1.00 38.85 C ATOM 94 C PHE A 19 31.711 48.376 10.439 1.00 44.93 C ATOM 95 O PHE A 19 30.766 49.097 10.246 1.00 46.80 O ATOM 96 CB PHE A 19 31.998 47.082 8.369 1.00 40.89 C ATOM 97 CG PHE A 19 31.989 45.792 7.601 1.00 47.57 C ATOM 98 CD1 PHE A 19 31.167 45.599 6.524 1.00 55.20 C ATOM 99 CD2 PHE A 19 32.844 44.735 7.949 1.00 47.36 C ATOM 100 CE1 PHE A 19 31.182 44.402 5.802 1.00 56.99 C ATOM 101 CE2 PHE A 19 32.854 43.544 7.262 1.00 46.62 C ATOM 102 CZ PHE A 19 32.009 43.355 6.189 1.00 53.26 C ATOM 103 N PHE A 20 32.739 48.712 11.185 1.00 38.02 N ATOM 104 CA PHE A 20 32.937 50.080 11.667 1.00 34.39 C ATOM 105 C PHE A 20 34.052 50.575 10.770 1.00 37.83 C ATOM 106 O PHE A 20 35.210 50.035 10.736 1.00 40.74 O ATOM 107 CB PHE A 20 33.250 50.025 13.166 1.00 36.51 C ATOM 108 CG PHE A 20 33.521 51.360 13.816 1.00 38.00 C ATOM 109 CD1 PHE A 20 32.623 51.851 14.765 1.00 35.69 C ATOM 110 CD2 PHE A 20 34.606 52.122 13.442 1.00 32.74 C ATOM 111 CE1 PHE A 20 32.856 53.062 15.379 1.00 35.88 C ATOM 112 CE2 PHE A 20 34.844 53.325 14.073 1.00 39.30 C ATOM 113 CZ PHE A 20 33.935 53.827 15.000 1.00 33.67 C ATOM 114 N ILE A 21 33.758 51.565 9.971 1.00 34.10 N ATOM 115 CA ILE A 21 34.633 52.088 8.950 1.00 29.76 C ATOM 116 C ILE A 21 35.170 53.431 9.318 1.00 39.55 C ATOM 117 O ILE A 21 34.457 54.359 9.697 1.00 40.31 O ATOM 118 CB ILE A 21 33.915 52.085 7.591 1.00 33.73 C ATOM 119 CG1 ILE A 21 33.285 50.743 7.280 1.00 36.10 C ATOM 120 CG2 ILE A 21 34.775 52.557 6.440 1.00 35.30 C ATOM 121 CD1 ILE A 21 32.217 50.885 6.165 1.00 42.90 C ATOM 122 N ILE A 22 36.503 53.544 9.269 1.00 38.45 N ATOM 123 CA ILE A 22 37.222 54.740 9.642 1.00 41.29 C ATOM 124 C ILE A 22 37.853 55.254 8.361 1.00 44.27 C ATOM 125 O ILE A 22 38.437 54.442 7.636 1.00 41.38 O ATOM 126 CB ILE A 22 38.292 54.410 10.701 1.00 39.13 C ATOM 127 CG1 ILE A 22 37.679 54.035 12.049 1.00 39.22 C ATOM 128 CG2 ILE A 22 39.272 55.568 10.863 1.00 33.36 C ATOM 129 CD1 ILE A 22 38.762 53.618 13.075 1.00 37.22 C ATOM 130 N HIS A 23 37.764 56.538 8.072 1.00 40.19 N ATOM 131 CA HIS A 23 38.282 56.993 6.757 1.00 40.69 C ATOM 132 C HIS A 23 39.147 58.206 6.922 1.00 41.32 C ATOM 133 O HIS A 23 38.716 59.206 7.520 1.00 44.48 O ATOM 134 CB HIS A 23 37.060 57.162 5.838 1.00 46.20 C ATOM 135 CG HIS A 23 37.271 57.505 4.410 1.00 47.30 C ATOM 136 ND1 HIS A 23 38.478 57.360 3.701 1.00 48.99 N ATOM 137 CD2 HIS A 23 36.392 57.967 3.494 1.00 43.74 C ATOM 138 CE1 HIS A 23 38.309 57.774 2.438 1.00 43.09 C ATOM 139 NE2 HIS A 23 37.043 58.166 2.289 1.00 45.88 N ATOM 140 N LEU A 24 40.389 58.196 6.444 1.00 37.81 N ATOM 141 CA LEU A 24 41.318 59.317 6.508 1.00 34.77 C ATOM 142 C LEU A 24 40.935 60.150 5.284 1.00 39.72 C ATOM 143 O LEU A 24 40.994 59.570 4.201 1.00 32.43 O ATOM 144 CB LEU A 24 42.796 58.883 6.357 1.00 33.88 C ATOM 145 CG LEU A 24 43.221 57.755 7.376 1.00 40.01 C ATOM 146 CD1 LEU A 24 44.743 57.585 7.292 1.00 35.28 C ATOM 147 CD2 LEU A 24 42.801 58.146 8.791 1.00 39.39 C ATOM 148 N ILE A 25 40.520 61.428 5.466 1.00 42.34 N ATOM 149 CA ILE A 25 40.001 62.139 4.307 0.50 41.90 C ATOM 150 C ILE A 25 40.687 63.506 4.177 1.00 46.32 C ATOM 151 O ILE A 25 40.007 64.565 4.013 1.00 48.06 O ATOM 152 CB ILE A 25 38.478 62.307 4.364 0.50 43.26 C ATOM 153 CG1 ILE A 25 38.082 63.134 5.588 1.00 20.00 C ATOM 154 CG2 ILE A 25 37.798 60.946 4.389 1.00 20.00 C ATOM 155 CD1 ILE A 25 38.033 62.340 6.874 1.00 20.00 C ATOM 156 N ASN A 26 41.969 63.556 4.061 1.00 43.19 N ATOM 157 CA ASN A 26 42.830 64.687 3.873 1.00 40.19 C ATOM 158 C ASN A 26 43.903 64.419 2.828 1.00 40.93 C ATOM 159 O ASN A 26 45.105 64.557 3.062 1.00 43.60 O ATOM 160 CB ASN A 26 43.436 65.090 5.232 1.00 42.38 C ATOM 161 CG ASN A 26 44.054 66.480 5.188 1.00 54.19 C ATOM 162 OD1 ASN A 26 43.777 67.214 4.213 1.00 52.58 O ATOM 163 ND2 ASN A 26 44.875 66.793 6.187 1.00 41.86 N ATOM 164 N PRO A 27 43.466 64.071 1.622 1.00 43.73 N ATOM 165 CA PRO A 27 44.319 63.737 0.503 1.00 51.50 C ATOM 166 C PRO A 27 45.234 64.849 0.044 1.00 57.48 C ATOM 167 O PRO A 27 46.356 64.559 -0.362 1.00 53.93 O ATOM 168 CB PRO A 27 43.388 63.319 -0.626 1.00 49.55 C ATOM 169 CG PRO A 27 42.059 63.935 -0.268 1.00 50.96 C ATOM 170 CD PRO A 27 42.018 63.985 1.238 1.00 43.36 C ATOM 171 N ASP A 28 44.859 66.122 0.225 1.00 63.02 N ATOM 172 CA ASP A 28 45.746 67.208 -0.224 1.00 61.26 C ATOM 173 C ASP A 28 47.030 67.233 0.569 1.00 62.38 C ATOM 174 O ASP A 28 48.065 67.671 0.058 1.00 60.94 O ATOM 175 CB ASP A 28 45.033 68.556 -0.122 1.00 67.35 C ATOM 176 CG ASP A 28 43.758 68.595 -0.960 1.00 67.98 C ATOM 177 OD1 ASP A 28 43.699 67.905 -1.992 1.00 68.44 O ATOM 178 OD2 ASP A 28 42.812 69.320 -0.566 1.00 71.26 O ATOM 179 N ASN A 29 46.953 66.848 1.850 1.00 56.67 N ATOM 180 CA ASN A 29 48.112 66.815 2.724 1.00 56.49 C ATOM 181 C ASN A 29 48.637 65.376 2.885 1.00 53.40 C ATOM 182 O ASN A 29 49.333 65.082 3.866 1.00 50.24 O ATOM 183 CB ASN A 29 47.795 67.428 4.099 1.00 55.82 C ATOM 184 CG ASN A 29 49.024 67.887 4.862 1.00 67.55 C ATOM 185 OD1 ASN A 29 50.034 68.266 4.256 1.00 74.00 O ATOM 186 ND2 ASN A 29 49.042 67.961 6.201 1.00 66.78 N ATOM 187 N LEU A 30 48.236 64.474 2.011 1.00 48.23 N ATOM 188 CA LEU A 30 48.725 63.072 2.011 1.00 46.47 C ATOM 189 C LEU A 30 48.453 62.387 3.346 1.00 45.30 C ATOM 190 O LEU A 30 49.231 61.608 3.936 1.00 47.00 O ATOM 191 CB LEU A 30 50.201 63.008 1.676 1.00 45.92 C ATOM 192 CG LEU A 30 50.792 63.697 0.446 1.00 51.04 C ATOM 193 CD1 LEU A 30 52.317 63.572 0.455 1.00 49.78 C ATOM 194 CD2 LEU A 30 50.265 63.159 -0.867 1.00 47.56 C ATOM 195 N ASN A 31 47.313 62.671 3.929 1.00 45.53 N ATOM 196 CA ASN A 31 46.842 62.216 5.194 1.00 42.66 C ATOM 197 C ASN A 31 47.927 62.150 6.272 1.00 46.86 C ATOM 198 O ASN A 31 47.803 61.332 7.187 1.00 39.80 O ATOM 199 CB ASN A 31 46.079 60.900 5.069 1.00 40.87 C ATOM 200 CG ASN A 31 44.841 61.170 4.178 1.00 41.69 C ATOM 201 OD1 ASN A 31 43.843 61.686 4.720 1.00 45.29 O ATOM 202 ND2 ASN A 31 44.951 60.803 2.937 1.00 38.78 N ATOM 203 N ALA A 32 48.797 63.149 6.286 1.00 45.82 N ATOM 204 CA ALA A 32 49.710 63.432 7.372 1.00 51.60 C ATOM 205 C ALA A 32 48.839 63.651 8.621 1.00 50.06 C ATOM 206 O ALA A 32 47.751 64.195 8.539 1.00 45.62 O ATOM 207 CB ALA A 32 50.597 64.635 7.095 1.00 51.88 C ATOM 208 N LEU A 33 49.296 63.162 9.765 1.00 47.97 N ATOM 209 CA LEU A 33 48.507 63.257 10.973 1.00 47.31 C ATOM 210 C LEU A 33 49.282 63.951 12.091 1.00 45.47 C ATOM 211 O LEU A 33 50.499 63.858 12.237 1.00 47.61 O ATOM 212 CB LEU A 33 48.046 61.827 11.410 1.00 49.00 C ATOM 213 CG LEU A 33 47.281 61.007 10.349 1.00 50.05 C ATOM 214 CD1 LEU A 33 47.069 59.524 10.752 1.00 38.90 C ATOM 215 CD2 LEU A 33 45.934 61.668 10.051 1.00 41.94 C ATOM 216 N GLU A 34 48.557 64.717 12.887 1.00 46.88 N ATOM 217 CA GLU A 34 49.148 65.372 14.072 1.00 47.76 C ATOM 218 C GLU A 34 48.814 64.509 15.267 1.00 45.83 C ATOM 219 O GLU A 34 47.848 63.716 15.161 1.00 55.16 O ATOM 220 CB GLU A 34 48.520 66.778 14.232 1.00 53.04 C ATOM 221 CG GLU A 34 49.000 67.702 13.096 1.00 53.38 C ATOM 222 CD GLU A 34 48.479 69.117 13.261 1.00 63.37 C ATOM 223 OE1 GLU A 34 47.904 69.495 14.298 1.00 67.21 O ATOM 224 OE2 GLU A 34 48.669 69.905 12.312 1.00 74.09 O ATOM 225 N GLY A 35 49.304 64.864 16.444 1.00 42.31 N ATOM 226 CA GLY A 35 49.046 64.166 17.685 1.00 38.95 C ATOM 227 C GLY A 35 47.571 63.982 17.978 1.00 50.02 C ATOM 228 O GLY A 35 47.110 62.852 18.280 1.00 46.55 O ATOM 229 N GLU A 36 46.786 65.043 17.732 1.00 46.52 N ATOM 230 CA GLU A 36 45.370 65.012 18.029 1.00 49.62 C ATOM 231 C GLU A 36 44.654 64.061 17.041 1.00 34.10 C ATOM 232 O GLU A 36 43.632 63.538 17.437 1.00 42.27 O ATOM 233 CB GLU A 36 44.620 66.311 18.159 1.00 56.60 C ATOM 234 CG GLU A 36 44.893 67.674 17.675 1.00 70.98 C ATOM 235 CD GLU A 36 43.725 68.526 17.184 1.00 75.59 C ATOM 236 OE1 GLU A 36 42.809 68.888 17.961 1.00 78.26 O ATOM 237 OE2 GLU A 36 43.696 68.856 15.962 1.00 74.93 O ATOM 238 N ASP A 37 45.171 63.927 15.829 1.00 36.45 N ATOM 239 CA ASP A 37 44.535 62.988 14.860 1.00 43.39 C ATOM 240 C ASP A 37 44.804 61.534 15.290 1.00 39.77 C ATOM 241 O ASP A 37 43.866 60.724 15.397 1.00 37.31 O ATOM 242 CB ASP A 37 45.095 63.330 13.464 1.00 38.75 C ATOM 243 CG ASP A 37 44.837 64.824 13.151 1.00 46.68 C ATOM 244 OD1 ASP A 37 43.680 65.197 13.487 1.00 45.48 O ATOM 245 OD2 ASP A 37 45.741 65.532 12.668 1.00 41.64 O ATOM 246 N TYR A 38 46.011 61.297 15.828 1.00 39.05 N ATOM 247 CA TYR A 38 46.330 59.959 16.384 1.00 40.52 C ATOM 248 C TYR A 38 45.575 59.626 17.656 1.00 39.04 C ATOM 249 O TYR A 38 45.013 58.533 17.763 1.00 38.15 O ATOM 250 CB TYR A 38 47.817 59.835 16.690 1.00 35.37 C ATOM 251 CG TYR A 38 48.622 59.593 15.410 1.00 41.35 C ATOM 252 CD1 TYR A 38 49.606 60.493 15.070 1.00 34.69 C ATOM 253 CD2 TYR A 38 48.453 58.445 14.643 1.00 38.99 C ATOM 254 CE1 TYR A 38 50.328 60.334 13.905 1.00 38.63 C ATOM 255 CE2 TYR A 38 49.192 58.299 13.460 1.00 31.97 C ATOM 256 CZ TYR A 38 50.106 59.230 13.112 1.00 38.30 C ATOM 257 OH TYR A 38 50.898 59.092 11.973 1.00 44.50 O ATOM 258 N ILE A 39 45.294 60.633 18.502 1.00 43.22 N ATOM 259 CA ILE A 39 44.393 60.392 19.651 1.00 38.46 C ATOM 260 C ILE A 39 43.005 60.045 19.183 1.00 37.16 C ATOM 261 O ILE A 39 42.270 59.170 19.655 1.00 41.60 O ATOM 262 CB ILE A 39 44.289 61.710 20.496 1.00 44.80 C ATOM 263 CG1 ILE A 39 45.672 62.063 21.062 1.00 51.01 C ATOM 264 CG2 ILE A 39 43.301 61.599 21.660 1.00 43.01 C ATOM 265 CD1 ILE A 39 46.222 61.014 22.011 1.00 57.17 C ATOM 266 N TYR A 40 42.506 60.903 18.279 1.00 36.73 N ATOM 267 CA TYR A 40 41.152 60.708 17.725 1.00 37.83 C ATOM 268 C TYR A 40 41.031 59.323 17.085 1.00 35.84 C ATOM 269 O TYR A 40 40.104 58.525 17.403 1.00 35.05 O ATOM 270 CB TYR A 40 40.931 61.874 16.711 1.00 36.98 C ATOM 271 CG TYR A 40 39.485 61.848 16.221 1.00 44.92 C ATOM 272 CD1 TYR A 40 38.472 62.210 17.107 1.00 48.91 C ATOM 273 CD2 TYR A 40 39.132 61.491 14.928 1.00 40.27 C ATOM 274 CE1 TYR A 40 37.150 62.180 16.712 1.00 49.11 C ATOM 275 CE2 TYR A 40 37.806 61.475 14.533 1.00 41.72 C ATOM 276 CZ TYR A 40 36.820 61.798 15.433 1.00 45.79 C ATOM 277 OH TYR A 40 35.491 61.800 15.051 1.00 48.18 O ATOM 278 N LEU A 41 42.084 58.890 16.366 1.00 36.34 N ATOM 279 CA LEU A 41 42.054 57.484 15.809 1.00 39.14 C ATOM 280 C LEU A 41 41.946 56.434 16.894 1.00 27.81 C ATOM 281 O LEU A 41 41.120 55.481 16.848 1.00 34.64 O ATOM 282 CB LEU A 41 43.313 57.255 15.009 1.00 43.43 C ATOM 283 CG LEU A 41 43.441 56.626 13.648 1.00 54.53 C ATOM 284 CD1 LEU A 41 44.877 56.047 13.470 1.00 45.36 C ATOM 285 CD2 LEU A 41 42.414 55.555 13.309 1.00 51.05 C ATOM 286 N GLY A 42 42.660 56.649 17.999 1.00 34.02 N ATOM 287 CA GLY A 42 42.556 55.719 19.160 1.00 32.24 C ATOM 288 C GLY A 42 41.231 55.666 19.819 1.00 36.59 C ATOM 289 O GLY A 42 40.678 54.585 20.141 1.00 36.98 O ATOM 290 N GLU A 43 40.582 56.865 19.916 1.00 36.32 N ATOM 291 CA GLU A 43 39.232 56.944 20.469 1.00 40.09 C ATOM 292 C GLU A 43 38.200 56.299 19.573 1.00 31.26 C ATOM 293 O GLU A 43 37.194 55.750 20.029 1.00 40.00 O ATOM 294 CB GLU A 43 38.799 58.444 20.660 1.00 40.58 C ATOM 295 CG GLU A 43 39.736 59.171 21.641 1.00 48.58 C ATOM 296 CD GLU A 43 39.312 60.648 21.753 1.00 60.04 C ATOM 297 OE1 GLU A 43 38.854 61.240 20.735 1.00 58.97 O ATOM 298 OE2 GLU A 43 39.441 61.211 22.852 1.00 59.73 O ATOM 299 N LEU A 44 38.425 56.427 18.245 1.00 31.47 N ATOM 300 CA LEU A 44 37.515 55.713 17.317 1.00 34.65 C ATOM 301 C LEU A 44 37.606 54.208 17.505 1.00 39.54 C ATOM 302 O LEU A 44 36.600 53.492 17.592 1.00 40.58 O ATOM 303 CB LEU A 44 37.884 56.148 15.883 1.00 34.67 C ATOM 304 CG LEU A 44 37.403 57.570 15.495 1.00 40.66 C ATOM 305 CD1 LEU A 44 37.693 57.776 14.010 1.00 38.61 C ATOM 306 CD2 LEU A 44 35.886 57.744 15.784 1.00 35.63 C ATOM 307 N LEU A 45 38.858 53.704 17.685 1.00 35.74 N ATOM 308 CA LEU A 45 38.988 52.234 17.912 1.00 36.17 C ATOM 309 C LEU A 45 38.343 51.820 19.215 1.00 30.21 C ATOM 310 O LEU A 45 37.690 50.774 19.321 1.00 35.63 O ATOM 311 CB LEU A 45 40.475 51.847 17.950 1.00 33.07 C ATOM 312 CG LEU A 45 41.004 51.266 16.602 1.00 38.26 C ATOM 313 CD1 LEU A 45 41.130 52.315 15.528 1.00 31.13 C ATOM 314 CD2 LEU A 45 42.369 50.597 16.893 1.00 34.96 C ATOM 315 N GLU A 46 38.446 52.648 20.265 1.00 32.71 N ATOM 316 CA GLU A 46 37.693 52.402 21.500 1.00 37.59 C ATOM 317 C GLU A 46 36.186 52.333 21.283 1.00 38.25 C ATOM 318 O GLU A 46 35.476 51.465 21.835 1.00 39.77 O ATOM 319 CB GLU A 46 37.923 53.579 22.505 1.00 39.36 C ATOM 320 CG GLU A 46 39.363 53.700 22.962 1.00 51.06 C ATOM 321 CD GLU A 46 39.537 54.802 24.015 1.00 65.58 C ATOM 322 OE1 GLU A 46 38.503 55.163 24.664 1.00 67.70 O ATOM 323 OE2 GLU A 46 40.683 55.302 24.156 1.00 57.74 O ATOM 324 N LEU A 47 35.674 53.265 20.470 1.00 38.96 N ATOM 325 CA LEU A 47 34.215 53.247 20.185 1.00 41.65 C ATOM 326 C LEU A 47 33.850 51.982 19.435 1.00 40.74 C ATOM 327 O LEU A 47 32.973 51.185 19.812 1.00 39.27 O ATOM 328 CB LEU A 47 33.938 54.467 19.262 1.00 44.14 C ATOM 329 CG LEU A 47 32.554 55.047 19.151 1.00 55.57 C ATOM 330 CD1 LEU A 47 31.927 55.327 20.563 1.00 52.79 C ATOM 331 CD2 LEU A 47 32.621 56.367 18.354 1.00 47.78 C ATOM 332 N ALA A 48 34.708 51.640 18.422 1.00 35.31 N ATOM 333 CA ALA A 48 34.370 50.347 17.720 1.00 34.86 C ATOM 334 C ALA A 48 34.451 49.170 18.611 1.00 29.99 C ATOM 335 O ALA A 48 33.672 48.157 18.596 1.00 34.46 O ATOM 336 CB ALA A 48 35.379 50.222 16.543 1.00 35.12 C ATOM 337 N ASP A 49 35.452 49.180 19.536 1.00 33.11 N ATOM 338 CA ASP A 49 35.711 48.010 20.400 1.00 30.98 C ATOM 339 C ASP A 49 34.560 47.775 21.369 1.00 43.95 C ATOM 340 O ASP A 49 34.330 46.622 21.790 1.00 37.64 O ATOM 341 CB ASP A 49 37.002 48.226 21.221 1.00 39.58 C ATOM 342 CG ASP A 49 37.720 46.982 21.693 1.00 40.85 C ATOM 343 OD1 ASP A 49 38.078 46.897 22.902 1.00 41.93 O ATOM 344 OD2 ASP A 49 37.926 46.008 20.948 1.00 38.27 O ATOM 345 N ARG A 50 33.830 48.875 21.692 1.00 43.51 N ATOM 346 CA ARG A 50 32.771 48.707 22.714 1.00 50.73 C ATOM 347 C ARG A 50 31.404 48.520 22.088 1.00 47.30 C ATOM 348 O ARG A 50 30.399 48.253 22.741 1.00 49.57 O ATOM 349 CB ARG A 50 32.752 49.882 23.694 1.00 55.29 C ATOM 350 CG ARG A 50 33.997 50.098 24.518 1.00 70.99 C ATOM 351 CD ARG A 50 34.395 48.824 25.266 1.00 87.83 C ATOM 352 NE ARG A 50 35.658 48.946 25.994 1.00100.56 N ATOM 353 CZ ARG A 50 35.938 48.378 27.165 1.00104.56 C ATOM 354 NH1 ARG A 50 35.044 47.613 27.790 1.00107.33 N ATOM 355 NH2 ARG A 50 37.130 48.569 27.730 1.00106.72 N ATOM 356 N ASN A 51 31.326 48.685 20.773 1.00 48.80 N ATOM 357 CA ASN A 51 30.077 48.430 20.045 1.00 41.09 C ATOM 358 C ASN A 51 29.886 46.943 19.831 1.00 44.65 C ATOM 359 O ASN A 51 30.415 46.275 18.922 1.00 40.50 O ATOM 360 CB ASN A 51 30.086 49.229 18.755 1.00 43.13 C ATOM 361 CG ASN A 51 28.727 49.170 18.037 1.00 39.08 C ATOM 362 OD1 ASN A 51 28.058 48.149 18.003 1.00 43.16 O ATOM 363 ND2 ASN A 51 28.466 50.240 17.326 1.00 39.62 N ATOM 364 N ARG A 52 28.912 46.363 20.537 1.00 43.39 N ATOM 365 CA ARG A 52 28.604 44.952 20.405 1.00 53.31 C ATOM 366 C ARG A 52 28.091 44.565 19.036 1.00 46.12 C ATOM 367 O ARG A 52 28.067 43.367 18.779 1.00 48.44 O ATOM 368 CB ARG A 52 27.633 44.490 21.510 1.00 61.73 C ATOM 369 CG ARG A 52 28.187 44.918 22.894 1.00 77.15 C ATOM 370 CD ARG A 52 29.452 44.127 23.207 1.00 86.85 C ATOM 371 NE ARG A 52 29.959 44.338 24.544 1.00 96.89 N ATOM 372 CZ ARG A 52 30.602 43.457 25.308 1.00104.11 C ATOM 373 NH1 ARG A 52 30.845 42.209 24.903 1.00103.88 N ATOM 374 NH2 ARG A 52 30.986 43.859 26.529 1.00105.49 N ATOM 375 N ASP A 53 27.726 45.474 18.139 1.00 42.52 N ATOM 376 CA ASP A 53 27.333 45.061 16.799 1.00 43.22 C ATOM 377 C ASP A 53 28.551 45.049 15.866 1.00 44.36 C ATOM 378 O ASP A 53 28.346 44.677 14.711 1.00 41.50 O ATOM 379 CB ASP A 53 26.341 46.049 16.160 1.00 55.99 C ATOM 380 CG ASP A 53 25.032 46.170 16.943 1.00 58.71 C ATOM 381 OD1 ASP A 53 24.533 45.164 17.475 1.00 53.26 O ATOM 382 OD2 ASP A 53 24.555 47.323 16.983 1.00 66.34 O ATOM 383 N VAL A 54 29.642 45.711 16.269 1.00 36.84 N ATOM 384 CA VAL A 54 30.773 45.724 15.275 1.00 38.09 C ATOM 385 C VAL A 54 31.635 44.475 15.407 1.00 44.18 C ATOM 386 O VAL A 54 31.925 44.036 16.550 1.00 40.81 O ATOM 387 CB VAL A 54 31.578 46.970 15.591 1.00 36.27 C ATOM 388 CG1 VAL A 54 32.983 46.966 15.010 1.00 31.39 C ATOM 389 CG2 VAL A 54 30.768 48.216 15.136 1.00 36.34 C ATOM 390 N TYR A 55 31.998 43.843 14.270 1.00 40.97 N ATOM 391 CA TYR A 55 32.932 42.727 14.305 1.00 32.89 C ATOM 392 C TYR A 55 34.249 43.019 13.627 1.00 38.72 C ATOM 393 O TYR A 55 35.276 42.333 13.828 1.00 36.75 O ATOM 394 CB TYR A 55 32.314 41.419 13.776 1.00 36.48 C ATOM 395 CG TYR A 55 31.191 40.967 14.676 1.00 41.06 C ATOM 396 CD1 TYR A 55 29.909 41.562 14.554 1.00 40.05 C ATOM 397 CD2 TYR A 55 31.410 40.023 15.652 1.00 34.42 C ATOM 398 CE1 TYR A 55 28.893 41.134 15.413 1.00 40.32 C ATOM 399 CE2 TYR A 55 30.427 39.603 16.521 1.00 43.94 C ATOM 400 CZ TYR A 55 29.153 40.187 16.371 1.00 43.67 C ATOM 401 OH TYR A 55 28.173 39.762 17.232 1.00 46.56 O ATOM 402 N PHE A 56 34.295 43.938 12.690 1.00 34.76 N ATOM 403 CA PHE A 56 35.428 44.329 11.907 1.00 35.94 C ATOM 404 C PHE A 56 35.600 45.851 11.954 1.00 39.42 C ATOM 405 O PHE A 56 34.582 46.553 11.841 1.00 42.26 O ATOM 406 CB PHE A 56 35.227 43.981 10.388 1.00 35.23 C ATOM 407 CG PHE A 56 35.048 42.517 10.179 1.00 34.29 C ATOM 408 CD1 PHE A 56 33.811 41.933 10.356 1.00 35.62 C ATOM 409 CD2 PHE A 56 36.132 41.704 9.863 1.00 35.82 C ATOM 410 CE1 PHE A 56 33.644 40.579 10.253 1.00 38.22 C ATOM 411 CE2 PHE A 56 35.963 40.331 9.721 1.00 38.29 C ATOM 412 CZ PHE A 56 34.707 39.764 9.922 1.00 35.44 C ATOM 413 N THR A 57 36.827 46.286 12.070 1.00 34.44 N ATOM 414 CA THR A 57 37.189 47.700 12.077 1.00 28.64 C ATOM 415 C THR A 57 38.058 47.921 10.870 1.00 34.42 C ATOM 416 O THR A 57 39.166 47.343 10.719 1.00 32.93 O ATOM 417 CB THR A 57 37.857 48.112 13.403 1.00 32.00 C ATOM 418 OG1 THR A 57 36.906 47.918 14.473 1.00 31.92 O ATOM 419 CG2 THR A 57 38.291 49.568 13.400 1.00 28.15 C ATOM 420 N ILE A 58 37.476 48.608 9.875 1.00 35.38 N ATOM 421 CA ILE A 58 38.173 48.815 8.595 1.00 28.48 C ATOM 422 C ILE A 58 38.765 50.195 8.525 1.00 39.74 C ATOM 423 O ILE A 58 38.066 51.233 8.665 1.00 41.30 O ATOM 424 CB ILE A 58 37.145 48.636 7.445 1.00 32.34 C ATOM 425 CG1 ILE A 58 36.307 47.425 7.603 1.00 33.66 C ATOM 426 CG2 ILE A 58 37.905 48.703 6.071 1.00 27.22 C ATOM 427 CD1 ILE A 58 37.137 46.099 7.599 1.00 39.28 C ATOM 428 N ILE A 59 40.066 50.276 8.236 1.00 32.19 N ATOM 429 CA ILE A 59 40.735 51.565 8.131 1.00 28.85 C ATOM 430 C ILE A 59 40.968 51.851 6.656 1.00 34.86 C ATOM 431 O ILE A 59 41.635 51.055 5.984 1.00 32.87 O ATOM 432 CB ILE A 59 42.071 51.547 8.913 1.00 33.41 C ATOM 433 CG1 ILE A 59 41.666 51.206 10.395 1.00 38.09 C ATOM 434 CG2 ILE A 59 42.730 52.907 8.880 1.00 30.40 C ATOM 435 CD1 ILE A 59 42.854 51.199 11.306 1.00 44.92 C ATOM 436 N GLN A 60 40.484 52.970 6.156 1.00 31.35 N ATOM 437 CA GLN A 60 40.545 53.378 4.750 1.00 35.20 C ATOM 438 C GLN A 60 41.034 54.803 4.663 1.00 37.32 C ATOM 439 O GLN A 60 41.039 55.506 5.682 1.00 35.00 O ATOM 440 CB GLN A 60 39.113 53.280 4.128 1.00 32.86 C ATOM 441 CG GLN A 60 38.559 51.850 4.203 1.00 32.50 C ATOM 442 CD GLN A 60 37.372 51.619 3.278 1.00 39.24 C ATOM 443 OE1 GLN A 60 36.502 52.521 3.246 1.00 34.28 O ATOM 444 NE2 GLN A 60 37.305 50.517 2.564 1.00 33.70 N ATOM 445 N SER A 61 41.705 55.126 3.549 1.00 37.26 N ATOM 446 CA SER A 61 42.223 56.498 3.420 1.00 37.01 C ATOM 447 C SER A 61 41.772 57.085 2.064 1.00 35.99 C ATOM 448 O SER A 61 40.874 56.468 1.421 1.00 43.61 O ATOM 449 CB SER A 61 43.713 56.423 3.564 1.00 34.85 C ATOM 450 OG SER A 61 44.387 57.642 3.614 1.00 38.40 O ATOM 451 N SER A 62 42.575 57.917 1.429 1.00 34.56 N ATOM 452 CA SER A 62 42.052 58.686 0.273 1.00 43.55 C ATOM 453 C SER A 62 43.211 59.283 -0.486 1.00 41.30 C ATOM 454 O SER A 62 44.234 59.568 0.166 1.00 37.63 O ATOM 455 CB SER A 62 41.209 59.913 0.803 1.00 38.50 C ATOM 456 OG SER A 62 42.036 60.743 1.627 1.00 40.10 O ATOM 457 N GLY A 63 43.062 59.484 -1.822 1.00 39.84 N ATOM 458 CA GLY A 63 44.233 60.107 -2.496 1.00 41.59 C ATOM 459 C GLY A 63 45.299 59.016 -2.795 1.00 43.94 C ATOM 460 O GLY A 63 45.027 57.814 -2.828 1.00 41.49 O ATOM 461 N ARG A 64 46.505 59.450 -3.089 1.00 39.42 N ATOM 462 CA ARG A 64 47.614 58.619 -3.503 1.00 47.07 C ATOM 463 C ARG A 64 48.462 58.036 -2.360 1.00 43.73 C ATOM 464 O ARG A 64 49.249 57.118 -2.600 1.00 42.10 O ATOM 465 CB ARG A 64 48.511 59.501 -4.428 1.00 43.58 C ATOM 466 CG ARG A 64 47.615 59.879 -5.705 1.00 52.58 C ATOM 467 CD ARG A 64 48.583 60.081 -6.870 1.00 54.41 C ATOM 468 NE ARG A 64 48.069 59.583 -8.141 1.00 62.68 N ATOM 469 CZ ARG A 64 48.662 58.745 -8.975 1.00 60.18 C ATOM 470 NH1 ARG A 64 49.845 58.216 -8.754 1.00 59.40 N ATOM 471 NH2 ARG A 64 47.983 58.469 -10.076 1.00 68.72 N ATOM 472 N PHE A 65 48.389 58.594 -1.172 1.00 43.79 N ATOM 473 CA PHE A 65 49.106 58.096 0.005 1.00 44.41 C ATOM 474 C PHE A 65 48.103 57.565 1.023 1.00 46.75 C ATOM 475 O PHE A 65 47.008 58.105 1.104 1.00 39.75 O ATOM 476 CB PHE A 65 49.901 59.195 0.717 1.00 38.67 C ATOM 477 CG PHE A 65 51.320 59.261 0.252 1.00 42.22 C ATOM 478 CD1 PHE A 65 51.587 59.596 -1.073 1.00 50.07 C ATOM 479 CD2 PHE A 65 52.378 59.059 1.118 1.00 45.70 C ATOM 480 CE1 PHE A 65 52.882 59.648 -1.562 1.00 46.56 C ATOM 481 CE2 PHE A 65 53.682 59.118 0.651 1.00 47.85 C ATOM 482 CZ PHE A 65 53.910 59.394 -0.687 1.00 50.88 C ATOM 483 N PHE A 66 48.504 56.512 1.780 1.00 41.09 N ATOM 484 CA PHE A 66 47.614 56.061 2.851 1.00 34.50 C ATOM 485 C PHE A 66 47.800 57.136 3.948 1.00 32.60 C ATOM 486 O PHE A 66 46.874 57.686 4.527 1.00 39.08 O ATOM 487 CB PHE A 66 48.041 54.668 3.368 1.00 38.92 C ATOM 488 CG PHE A 66 47.255 54.242 4.586 1.00 35.64 C ATOM 489 CD1 PHE A 66 46.034 53.621 4.476 1.00 33.88 C ATOM 490 CD2 PHE A 66 47.796 54.485 5.843 1.00 35.17 C ATOM 491 CE1 PHE A 66 45.354 53.187 5.621 1.00 35.75 C ATOM 492 CE2 PHE A 66 47.071 54.104 6.968 1.00 29.85 C ATOM 493 CZ PHE A 66 45.870 53.466 6.877 1.00 31.75 C ATOM 494 N SER A 67 49.048 57.512 4.109 1.00 28.80 N ATOM 495 CA SER A 67 49.499 58.485 5.080 1.00 36.36 C ATOM 496 C SER A 67 51.013 58.672 5.046 1.00 43.96 C ATOM 497 O SER A 67 51.814 57.728 5.161 1.00 48.98 O ATOM 498 CB SER A 67 49.071 58.114 6.517 1.00 34.98 C ATOM 499 OG SER A 67 49.581 59.109 7.430 1.00 40.49 O ATOM 500 N SER A 68 51.470 59.921 5.021 1.00 45.74 N ATOM 501 CA SER A 68 52.842 60.332 5.121 1.00 44.74 C ATOM 502 C SER A 68 53.337 60.391 6.564 1.00 48.49 C ATOM 503 O SER A 68 54.504 60.709 6.777 1.00 52.51 O ATOM 504 CB SER A 68 53.062 61.722 4.483 1.00 56.70 C ATOM 505 OG SER A 68 52.125 62.655 5.049 1.00 58.49 O ATOM 506 N GLY A 69 52.616 59.957 7.580 1.00 49.52 N ATOM 507 CA GLY A 69 53.150 59.893 8.929 1.00 54.20 C ATOM 508 C GLY A 69 52.828 61.160 9.750 1.00 57.77 C ATOM 509 O GLY A 69 51.824 61.804 9.503 1.00 48.10 O ATOM 510 N ALA A 70 53.650 61.408 10.781 1.00 54.91 N ATOM 511 CA ALA A 70 53.481 62.564 11.641 1.00 60.33 C ATOM 512 C ALA A 70 53.591 63.917 10.926 1.00 57.35 C ATOM 513 O ALA A 70 54.426 64.175 10.058 1.00 56.20 O ATOM 514 CB ALA A 70 54.459 62.473 12.810 1.00 54.67 C ATOM 515 N ASP A 71 52.621 64.782 11.222 1.00 55.68 N ATOM 516 CA ASP A 71 52.598 66.130 10.605 1.00 65.72 C ATOM 517 C ASP A 71 53.333 67.125 11.517 1.00 65.17 C ATOM 518 O ASP A 71 52.896 67.275 12.662 1.00 65.22 O ATOM 519 CB ASP A 71 51.161 66.612 10.442 1.00 62.50 C ATOM 520 CG ASP A 71 50.987 67.774 9.486 1.00 71.05 C ATOM 521 OD1 ASP A 71 51.989 68.430 9.135 1.00 70.69 O ATOM 522 OD2 ASP A 71 49.817 68.030 9.079 1.00 72.00 O ATOM 523 N PHE A 72 54.472 67.661 11.107 1.00 73.01 N ATOM 524 CA PHE A 72 55.117 68.689 11.934 1.00 83.54 C ATOM 525 C PHE A 72 54.825 70.105 11.418 1.00 88.07 C ATOM 526 O PHE A 72 55.505 70.530 10.482 1.00 87.30 O ATOM 527 CB PHE A 72 56.629 68.500 11.959 1.00 83.19 C ATOM 528 CG PHE A 72 57.089 67.098 12.173 1.00 83.43 C ATOM 529 CD1 PHE A 72 56.703 66.378 13.297 1.00 84.32 C ATOM 530 CD2 PHE A 72 57.912 66.489 11.238 1.00 85.37 C ATOM 531 CE1 PHE A 72 57.130 65.072 13.478 1.00 84.50 C ATOM 532 CE2 PHE A 72 58.352 65.187 11.423 1.00 84.47 C ATOM 533 CZ PHE A 72 57.960 64.482 12.543 1.00 84.07 C ATOM 534 N LYS A 73 53.878 70.813 12.027 1.00 94.45 N ATOM 535 CA LYS A 73 53.568 72.196 11.652 1.00 97.06 C ATOM 536 C LYS A 73 53.831 72.442 10.159 1.00 96.74 C ATOM 537 O LYS A 73 53.324 71.648 9.330 1.00 95.77 O ATOM 538 CB LYS A 73 54.349 73.223 12.470 1.00 98.59 C ATOM 539 CG LYS A 73 54.721 72.846 13.895 1.00101.21 C ATOM 540 CD LYS A 73 56.221 73.022 14.136 1.00103.20 C ATOM 541 CE LYS A 73 56.691 72.227 15.345 1.00104.73 C ATOM 542 NZ LYS A 73 58.182 72.139 15.433 1.00105.89 N ATOM 543 N GLU A 89 61.874 75.778 26.612 1.00117.62 N ATOM 544 CA GLU A 89 61.470 74.391 26.959 1.00116.21 C ATOM 545 C GLU A 89 59.962 74.195 26.976 1.00112.54 C ATOM 546 O GLU A 89 59.439 73.258 27.582 1.00112.35 O ATOM 547 CB GLU A 89 62.127 73.898 28.243 1.00119.16 C ATOM 548 CG GLU A 89 63.628 73.672 28.151 1.00122.97 C ATOM 549 CD GLU A 89 64.032 72.499 27.281 1.00124.25 C ATOM 550 OE1 GLU A 89 63.130 71.795 26.778 1.00125.70 O ATOM 551 OE2 GLU A 89 65.247 72.270 27.088 1.00125.16 O ATOM 552 N THR A 90 59.280 74.892 26.048 1.00108.43 N ATOM 553 CA THR A 90 57.888 74.532 25.691 1.00104.08 C ATOM 554 C THR A 90 58.035 73.365 24.690 1.00101.65 C ATOM 555 O THR A 90 57.161 72.562 24.419 1.00 99.92 O ATOM 556 CB THR A 90 57.119 75.718 25.129 1.00104.48 C ATOM 557 OG1 THR A 90 56.508 76.426 26.250 1.00106.02 O ATOM 558 CG2 THR A 90 55.999 75.363 24.162 1.00106.79 C ATOM 559 N SER A 91 59.270 73.195 24.227 1.00 95.67 N ATOM 560 CA SER A 91 59.877 72.174 23.462 1.00 92.72 C ATOM 561 C SER A 91 59.841 70.821 24.179 1.00 91.75 C ATOM 562 O SER A 91 59.433 69.830 23.535 1.00 85.32 O ATOM 563 CB SER A 91 61.357 72.443 23.126 1.00 93.52 C ATOM 564 OG SER A 91 61.469 73.149 21.896 1.00 95.50 O ATOM 565 N LYS A 92 59.715 70.813 25.506 1.00 91.83 N ATOM 566 CA LYS A 92 59.244 69.631 26.215 1.00 94.12 C ATOM 567 C LYS A 92 57.842 69.184 25.766 1.00 93.14 C ATOM 568 O LYS A 92 57.338 68.233 26.375 1.00 90.89 O ATOM 569 CB LYS A 92 59.286 69.871 27.723 1.00 94.67 C ATOM 570 CG LYS A 92 60.370 69.163 28.507 1.00 96.07 C ATOM 571 CD LYS A 92 60.011 69.191 29.996 1.00 99.70 C ATOM 572 CE LYS A 92 60.818 68.179 30.806 1.00103.52 C ATOM 573 NZ LYS A 92 60.428 66.778 30.449 1.00101.57 N ATOM 574 N TRP A 93 57.322 69.513 24.616 1.00 93.51 N ATOM 575 CA TRP A 93 56.294 69.217 23.679 1.00 87.31 C ATOM 576 C TRP A 93 56.428 67.816 23.053 1.00 81.60 C ATOM 577 O TRP A 93 55.572 67.243 22.378 1.00 72.66 O ATOM 578 CB TRP A 93 56.300 70.223 22.528 1.00 94.25 C ATOM 579 CG TRP A 93 55.521 70.041 21.278 1.00100.31 C ATOM 580 CD1 TRP A 93 54.250 70.491 21.017 1.00103.02 C ATOM 581 CD2 TRP A 93 55.938 69.383 20.064 1.00104.00 C ATOM 582 NE1 TRP A 93 53.860 70.145 19.743 1.00103.97 N ATOM 583 CE2 TRP A 93 54.881 69.463 19.137 1.00104.21 C ATOM 584 CE3 TRP A 93 57.115 68.721 19.685 1.00106.61 C ATOM 585 CZ2 TRP A 93 54.959 68.912 17.859 1.00106.92 C ATOM 586 CZ3 TRP A 93 57.195 68.171 18.416 1.00108.13 C ATOM 587 CH2 TRP A 93 56.122 68.271 17.516 1.00108.75 C ATOM 588 N VAL A 94 57.569 67.201 23.307 1.00 74.50 N ATOM 589 CA VAL A 94 57.894 65.851 22.953 1.00 71.56 C ATOM 590 C VAL A 94 57.234 64.885 23.953 1.00 70.62 C ATOM 591 O VAL A 94 56.953 63.723 23.632 1.00 65.74 O ATOM 592 CB VAL A 94 59.421 65.655 22.901 1.00 73.72 C ATOM 593 CG1 VAL A 94 60.078 66.704 21.988 1.00 74.75 C ATOM 594 CG2 VAL A 94 60.069 65.703 24.257 1.00 72.65 C ATOM 595 N SER A 95 56.749 65.397 25.103 1.00 58.26 N ATOM 596 CA SER A 95 56.023 64.530 26.024 1.00 60.80 C ATOM 597 C SER A 95 54.625 64.239 25.478 1.00 59.61 C ATOM 598 O SER A 95 54.126 63.117 25.598 1.00 52.34 O ATOM 599 CB SER A 95 55.946 65.096 27.443 1.00 63.73 C ATOM 600 OG SER A 95 55.128 66.266 27.462 1.00 68.01 O ATOM 601 N ASN A 96 54.027 65.208 24.782 1.00 60.95 N ATOM 602 CA ASN A 96 52.680 65.000 24.251 1.00 71.31 C ATOM 603 C ASN A 96 52.756 64.178 22.959 1.00 66.89 C ATOM 604 O ASN A 96 51.946 63.322 22.667 1.00 62.47 O ATOM 605 CB ASN A 96 51.899 66.305 24.084 1.00 72.71 C ATOM 606 CG ASN A 96 51.453 66.805 25.458 1.00 80.33 C ATOM 607 OD1 ASN A 96 51.587 67.990 25.759 1.00 89.74 O ATOM 608 ND2 ASN A 96 51.005 65.899 26.314 1.00 85.14 N ATOM 609 N PHE A 97 53.900 64.261 22.328 1.00 66.38 N ATOM 610 CA PHE A 97 54.284 63.492 21.175 1.00 69.98 C ATOM 611 C PHE A 97 54.438 62.001 21.481 1.00 64.28 C ATOM 612 O PHE A 97 53.824 61.109 20.915 1.00 69.29 O ATOM 613 CB PHE A 97 55.681 64.040 20.758 1.00 75.71 C ATOM 614 CG PHE A 97 56.079 63.364 19.471 1.00 81.72 C ATOM 615 CD1 PHE A 97 55.504 63.776 18.285 1.00 82.85 C ATOM 616 CD2 PHE A 97 56.982 62.310 19.483 1.00 82.94 C ATOM 617 CE1 PHE A 97 55.848 63.146 17.091 1.00 85.01 C ATOM 618 CE2 PHE A 97 57.326 61.681 18.298 1.00 84.21 C ATOM 619 CZ PHE A 97 56.756 62.107 17.108 1.00 84.04 C ATOM 620 N VAL A 98 55.251 61.698 22.463 1.00 51.91 N ATOM 621 CA VAL A 98 55.483 60.397 23.012 1.00 55.92 C ATOM 622 C VAL A 98 54.225 59.851 23.653 1.00 57.75 C ATOM 623 O VAL A 98 53.852 58.681 23.429 1.00 54.58 O ATOM 624 CB VAL A 98 56.706 60.426 23.942 1.00 57.20 C ATOM 625 CG1 VAL A 98 56.889 59.171 24.760 1.00 61.06 C ATOM 626 CG2 VAL A 98 57.939 60.670 23.052 1.00 54.80 C ATOM 627 N ALA A 99 53.418 60.738 24.259 1.00 49.94 N ATOM 628 CA ALA A 99 52.190 60.245 24.894 1.00 49.59 C ATOM 629 C ALA A 99 51.142 59.896 23.850 1.00 45.12 C ATOM 630 O ALA A 99 50.407 58.880 23.952 1.00 44.76 O ATOM 631 CB ALA A 99 51.709 61.204 25.954 1.00 48.79 C ATOM 632 N ARG A 100 51.155 60.602 22.735 1.00 44.20 N ATOM 633 CA ARG A 100 50.165 60.290 21.692 1.00 49.15 C ATOM 634 C ARG A 100 50.557 59.039 20.908 1.00 46.47 C ATOM 635 O ARG A 100 49.668 58.251 20.621 1.00 43.32 O ATOM 636 CB ARG A 100 49.992 61.535 20.817 1.00 58.15 C ATOM 637 CG ARG A 100 49.126 62.549 21.627 1.00 60.09 C ATOM 638 CD ARG A 100 49.459 63.949 21.175 1.00 66.27 C ATOM 639 NE ARG A 100 48.860 64.952 22.045 1.00 76.56 N ATOM 640 CZ ARG A 100 48.942 66.256 21.754 1.00 78.84 C ATOM 641 NH1 ARG A 100 49.574 66.617 20.638 1.00 81.18 N ATOM 642 NH2 ARG A 100 48.370 67.127 22.565 1.00 77.73 N ATOM 643 N ASN A 101 51.841 58.811 20.654 1.00 43.65 N ATOM 644 CA ASN A 101 52.275 57.567 20.036 1.00 50.32 C ATOM 645 C ASN A 101 51.899 56.341 20.875 1.00 50.36 C ATOM 646 O ASN A 101 51.387 55.381 20.290 1.00 48.69 O ATOM 647 CB ASN A 101 53.772 57.505 19.795 1.00 53.65 C ATOM 648 CG ASN A 101 54.273 58.489 18.770 1.00 57.38 C ATOM 649 OD1 ASN A 101 53.601 59.450 18.397 1.00 58.04 O ATOM 650 ND2 ASN A 101 55.491 58.234 18.303 1.00 60.47 N ATOM 651 N VAL A 102 52.180 56.343 22.173 1.00 40.94 N ATOM 652 CA VAL A 102 51.848 55.209 23.049 1.00 36.35 C ATOM 653 C VAL A 102 50.388 54.905 23.111 1.00 40.14 C ATOM 654 O VAL A 102 49.923 53.746 23.149 1.00 34.80 O ATOM 655 CB VAL A 102 52.406 55.546 24.473 1.00 42.14 C ATOM 656 CG1 VAL A 102 51.997 54.613 25.595 1.00 39.37 C ATOM 657 CG2 VAL A 102 53.921 55.606 24.337 1.00 42.03 C ATOM 658 N TYR A 103 49.592 56.006 23.173 1.00 35.52 N ATOM 659 CA TYR A 103 48.157 55.829 23.375 1.00 33.54 C ATOM 660 C TYR A 103 47.533 55.159 22.129 1.00 29.59 C ATOM 661 O TYR A 103 46.742 54.215 22.275 1.00 34.23 O ATOM 662 CB TYR A 103 47.525 57.226 23.650 1.00 33.72 C ATOM 663 CG TYR A 103 46.025 57.188 23.491 1.00 36.85 C ATOM 664 CD1 TYR A 103 45.251 56.729 24.546 1.00 38.93 C ATOM 665 CD2 TYR A 103 45.410 57.586 22.300 1.00 40.36 C ATOM 666 CE1 TYR A 103 43.873 56.609 24.407 1.00 45.14 C ATOM 667 CE2 TYR A 103 44.017 57.542 22.193 1.00 36.96 C ATOM 668 CZ TYR A 103 43.278 57.020 23.214 1.00 41.35 C ATOM 669 OH TYR A 103 41.916 56.939 23.121 1.00 40.93 O ATOM 670 N VAL A 104 47.816 55.605 20.948 1.00 35.75 N ATOM 671 CA VAL A 104 47.257 55.064 19.705 1.00 35.68 C ATOM 672 C VAL A 104 47.875 53.687 19.398 1.00 32.75 C ATOM 673 O VAL A 104 47.128 52.744 19.081 1.00 30.58 O ATOM 674 CB VAL A 104 47.391 56.022 18.492 1.00 36.70 C ATOM 675 CG1 VAL A 104 48.802 56.075 17.947 1.00 32.13 C ATOM 676 CG2 VAL A 104 46.413 55.578 17.364 1.00 33.21 C ATOM 677 N THR A 105 49.153 53.478 19.763 1.00 33.78 N ATOM 678 CA THR A 105 49.700 52.085 19.583 1.00 34.17 C ATOM 679 C THR A 105 48.980 51.094 20.461 1.00 35.20 C ATOM 680 O THR A 105 48.632 49.939 20.129 1.00 30.53 O ATOM 681 CB THR A 105 51.209 52.138 19.933 1.00 37.21 C ATOM 682 OG1 THR A 105 51.797 53.090 19.038 1.00 31.59 O ATOM 683 CG2 THR A 105 51.855 50.767 19.756 1.00 34.37 C ATOM 684 N ASP A 106 48.831 51.476 21.751 1.00 31.87 N ATOM 685 CA ASP A 106 48.116 50.625 22.721 1.00 31.00 C ATOM 686 C ASP A 106 46.686 50.341 22.285 1.00 35.18 C ATOM 687 O ASP A 106 46.142 49.213 22.349 1.00 31.36 O ATOM 688 CB ASP A 106 48.153 51.421 24.085 1.00 33.21 C ATOM 689 CG ASP A 106 47.361 50.609 25.098 1.00 38.74 C ATOM 690 OD1 ASP A 106 47.906 49.630 25.636 1.00 35.11 O ATOM 691 OD2 ASP A 106 46.170 50.941 25.268 1.00 38.80 O ATOM 692 N ALA A 107 46.011 51.340 21.681 1.00 33.45 N ATOM 693 CA ALA A 107 44.676 51.112 21.153 1.00 36.65 C ATOM 694 C ALA A 107 44.696 50.050 20.022 1.00 33.50 C ATOM 695 O ALA A 107 43.710 49.290 19.991 1.00 33.76 O ATOM 696 CB ALA A 107 44.024 52.404 20.618 1.00 34.25 C ATOM 697 N PHE A 108 45.673 50.078 19.122 1.00 30.51 N ATOM 698 CA PHE A 108 45.716 49.047 18.040 1.00 34.44 C ATOM 699 C PHE A 108 46.047 47.672 18.612 1.00 28.90 C ATOM 700 O PHE A 108 45.380 46.643 18.397 1.00 29.80 O ATOM 701 CB PHE A 108 46.709 49.487 16.956 1.00 29.65 C ATOM 702 CG PHE A 108 46.073 50.375 15.884 1.00 36.84 C ATOM 703 CD1 PHE A 108 45.781 51.724 16.147 1.00 30.79 C ATOM 704 CD2 PHE A 108 45.838 49.895 14.615 1.00 33.96 C ATOM 705 CE1 PHE A 108 45.147 52.506 15.222 1.00 29.46 C ATOM 706 CE2 PHE A 108 45.267 50.722 13.631 1.00 34.99 C ATOM 707 CZ PHE A 108 44.876 52.019 13.935 1.00 32.65 C ATOM 708 N ILE A 109 47.011 47.643 19.569 1.00 28.97 N ATOM 709 CA ILE A 109 47.422 46.359 20.171 1.00 31.72 C ATOM 710 C ILE A 109 46.291 45.650 20.843 1.00 32.21 C ATOM 711 O ILE A 109 46.166 44.412 20.818 1.00 30.63 O ATOM 712 CB ILE A 109 48.625 46.552 21.152 1.00 31.07 C ATOM 713 CG1 ILE A 109 49.891 46.907 20.379 1.00 32.49 C ATOM 714 CG2 ILE A 109 48.884 45.293 21.999 1.00 26.62 C ATOM 715 CD1 ILE A 109 51.023 47.506 21.246 1.00 31.09 C ATOM 716 N LYS A 110 45.441 46.378 21.614 1.00 34.01 N ATOM 717 CA LYS A 110 44.456 45.692 22.456 1.00 31.83 C ATOM 718 C LYS A 110 43.100 45.571 21.766 1.00 29.43 C ATOM 719 O LYS A 110 42.171 44.937 22.324 1.00 36.30 O ATOM 720 CB LYS A 110 44.257 46.516 23.761 1.00 34.39 C ATOM 721 CG LYS A 110 43.651 47.879 23.405 1.00 48.85 C ATOM 722 CD LYS A 110 42.789 48.511 24.471 1.00 63.05 C ATOM 723 CE LYS A 110 43.194 49.916 24.813 1.00 62.92 C ATOM 724 NZ LYS A 110 43.770 49.987 26.220 1.00 71.19 N ATOM 725 N HIS A 111 42.998 46.119 20.578 1.00 30.30 N ATOM 726 CA HIS A 111 41.651 46.104 19.911 1.00 29.75 C ATOM 727 C HIS A 111 41.164 44.706 19.770 1.00 34.38 C ATOM 728 O HIS A 111 41.932 43.862 19.319 1.00 33.55 O ATOM 729 CB HIS A 111 41.821 46.821 18.562 1.00 32.24 C ATOM 730 CG HIS A 111 40.505 47.234 17.942 1.00 38.47 C ATOM 731 ND1 HIS A 111 39.723 48.230 18.494 1.00 38.90 N ATOM 732 CD2 HIS A 111 39.871 46.806 16.815 1.00 31.10 C ATOM 733 CE1 HIS A 111 38.623 48.373 17.757 1.00 36.49 C ATOM 734 NE2 HIS A 111 38.696 47.561 16.735 1.00 34.79 N ATOM 735 N SER A 112 39.902 44.373 20.107 1.00 30.99 N ATOM 736 CA SER A 112 39.401 43.050 20.017 1.00 31.78 C ATOM 737 C SER A 112 38.653 42.690 18.732 1.00 32.80 C ATOM 738 O SER A 112 38.348 41.494 18.492 1.00 30.53 O ATOM 739 CB SER A 112 38.503 42.771 21.288 1.00 37.12 C ATOM 740 OG SER A 112 37.285 43.475 21.044 1.00 36.06 O ATOM 741 N LYS A 113 38.419 43.644 17.873 1.00 27.78 N ATOM 742 CA LYS A 113 37.655 43.419 16.625 1.00 34.43 C ATOM 743 C LYS A 113 38.723 43.240 15.503 1.00 35.58 C ATOM 744 O LYS A 113 39.865 43.643 15.742 1.00 35.29 O ATOM 745 CB LYS A 113 36.751 44.604 16.260 1.00 35.84 C ATOM 746 CG LYS A 113 35.869 45.076 17.495 1.00 35.32 C ATOM 747 CD LYS A 113 35.071 43.912 17.997 1.00 32.22 C ATOM 748 CE LYS A 113 34.180 44.208 19.204 1.00 44.70 C ATOM 749 NZ LYS A 113 33.128 45.248 18.910 1.00 38.25 N ATOM 750 N VAL A 114 38.345 42.607 14.427 1.00 31.88 N ATOM 751 CA VAL A 114 39.273 42.267 13.341 1.00 34.88 C ATOM 752 C VAL A 114 39.687 43.549 12.658 1.00 34.64 C ATOM 753 O VAL A 114 38.800 44.258 12.134 1.00 36.64 O ATOM 754 CB VAL A 114 38.584 41.281 12.372 1.00 34.26 C ATOM 755 CG1 VAL A 114 39.492 40.995 11.144 1.00 33.73 C ATOM 756 CG2 VAL A 114 38.161 39.994 13.045 1.00 29.90 C ATOM 757 N LEU A 115 40.973 43.906 12.677 1.00 30.24 N ATOM 758 CA LEU A 115 41.407 45.167 12.115 1.00 28.83 C ATOM 759 C LEU A 115 41.908 44.923 10.691 1.00 32.77 C ATOM 760 O LEU A 115 42.730 44.018 10.464 1.00 32.30 O ATOM 761 CB LEU A 115 42.577 45.810 12.873 1.00 33.96 C ATOM 762 CG LEU A 115 42.375 46.774 13.995 1.00 40.43 C ATOM 763 CD1 LEU A 115 43.626 46.925 14.859 1.00 35.39 C ATOM 764 CD2 LEU A 115 41.820 48.105 13.428 1.00 34.13 C ATOM 765 N ILE A 116 41.391 45.711 9.766 1.00 31.36 N ATOM 766 CA ILE A 116 41.666 45.563 8.339 1.00 31.32 C ATOM 767 C ILE A 116 42.099 46.861 7.740 1.00 34.86 C ATOM 768 O ILE A 116 41.355 47.878 7.835 1.00 35.11 O ATOM 769 CB ILE A 116 40.434 45.059 7.581 1.00 31.09 C ATOM 770 CG1 ILE A 116 39.944 43.756 8.115 1.00 38.17 C ATOM 771 CG2 ILE A 116 40.737 45.092 6.058 1.00 31.36 C ATOM 772 CD1 ILE A 116 38.863 43.041 7.321 1.00 36.94 C ATOM 773 N CYS A 117 43.288 46.851 7.150 1.00 31.69 N ATOM 774 CA CYS A 117 43.775 48.097 6.560 1.00 31.66 C ATOM 775 C CYS A 117 43.552 48.019 5.040 1.00 37.78 C ATOM 776 O CYS A 117 44.018 47.098 4.356 1.00 32.23 O ATOM 777 CB CYS A 117 45.263 48.309 6.902 1.00 27.80 C ATOM 778 SG CYS A 117 45.996 49.734 6.015 1.00 32.63 S ATOM 779 N CYS A 118 43.049 49.128 4.479 1.00 31.10 N ATOM 780 CA CYS A 118 42.918 49.175 2.999 1.00 32.49 C ATOM 781 C CYS A 118 44.018 50.101 2.608 1.00 30.93 C ATOM 782 O CYS A 118 43.822 51.305 2.787 1.00 32.49 O ATOM 783 CB CYS A 118 41.520 49.668 2.575 1.00 32.99 C ATOM 784 SG CYS A 118 40.181 48.558 3.022 1.00 34.09 S ATOM 785 N LEU A 119 45.138 49.576 2.101 1.00 32.01 N ATOM 786 CA LEU A 119 46.278 50.453 1.842 1.00 37.36 C ATOM 787 C LEU A 119 46.140 51.004 0.398 1.00 36.78 C ATOM 788 O LEU A 119 46.473 50.268 -0.540 1.00 31.54 O ATOM 789 CB LEU A 119 47.556 49.622 1.926 1.00 30.81 C ATOM 790 CG LEU A 119 48.814 49.848 2.606 1.00 40.32 C ATOM 791 CD1 LEU A 119 50.045 49.200 1.983 1.00 34.49 C ATOM 792 CD2 LEU A 119 49.064 51.162 3.301 1.00 31.19 C ATOM 793 N ASN A 120 45.769 52.265 0.274 1.00 39.06 N ATOM 794 CA ASN A 120 45.520 52.921 -1.001 1.00 42.31 C ATOM 795 C ASN A 120 46.771 53.618 -1.508 1.00 42.14 C ATOM 796 O ASN A 120 46.748 54.221 -2.571 1.00 42.10 O ATOM 797 CB ASN A 120 44.390 54.001 -0.855 1.00 39.75 C ATOM 798 CG ASN A 120 44.828 55.065 0.137 1.00 39.51 C ATOM 799 OD1 ASN A 120 45.245 54.746 1.279 1.00 35.54 O ATOM 800 ND2 ASN A 120 44.911 56.320 -0.284 1.00 37.63 N ATOM 801 N GLY A 121 47.864 53.517 -0.777 1.00 41.14 N ATOM 802 CA GLY A 121 49.175 54.035 -1.202 1.00 32.22 C ATOM 803 C GLY A 121 50.171 53.855 -0.052 1.00 35.31 C ATOM 804 O GLY A 121 49.897 53.179 0.952 1.00 30.72 O ATOM 805 N PRO A 122 51.346 54.443 -0.165 1.00 37.25 N ATOM 806 CA PRO A 122 52.352 54.354 0.876 1.00 38.24 C ATOM 807 C PRO A 122 51.932 54.883 2.234 1.00 39.81 C ATOM 808 O PRO A 122 51.099 55.767 2.394 1.00 35.56 O ATOM 809 CB PRO A 122 53.552 55.129 0.328 1.00 34.71 C ATOM 810 CG PRO A 122 53.308 55.254 -1.160 1.00 39.45 C ATOM 811 CD PRO A 122 51.800 55.248 -1.333 1.00 36.87 C ATOM 812 N ALA A 123 52.570 54.326 3.268 1.00 36.09 N ATOM 813 CA ALA A 123 52.372 54.723 4.665 1.00 33.91 C ATOM 814 C ALA A 123 53.799 54.870 5.224 1.00 36.17 C ATOM 815 O ALA A 123 54.698 54.136 4.875 1.00 35.25 O ATOM 816 CB ALA A 123 51.517 53.783 5.451 1.00 25.05 C ATOM 817 N ILE A 124 54.066 55.922 5.954 1.00 36.77 N ATOM 818 CA ILE A 124 55.364 56.283 6.493 1.00 37.18 C ATOM 819 C ILE A 124 55.255 56.549 8.016 1.00 37.05 C ATOM 820 O ILE A 124 54.198 56.966 8.479 1.00 40.41 O ATOM 821 CB ILE A 124 55.761 57.646 5.816 1.00 40.39 C ATOM 822 CG1 ILE A 124 55.771 57.452 4.294 1.00 41.61 C ATOM 823 CG2 ILE A 124 57.129 58.111 6.322 1.00 35.87 C ATOM 824 CD1 ILE A 124 56.491 58.462 3.466 1.00 52.36 C ATOM 825 N GLY A 125 56.252 56.220 8.783 1.00 37.09 N ATOM 826 CA GLY A 125 56.352 56.428 10.202 1.00 41.36 C ATOM 827 C GLY A 125 55.351 55.733 11.065 1.00 43.57 C ATOM 828 O GLY A 125 54.988 54.556 10.927 1.00 39.63 O ATOM 829 N LEU A 126 54.734 56.536 11.963 1.00 39.89 N ATOM 830 CA LEU A 126 53.820 55.938 12.943 1.00 34.73 C ATOM 831 C LEU A 126 52.680 55.299 12.242 1.00 36.20 C ATOM 832 O LEU A 126 52.166 54.229 12.628 1.00 36.85 O ATOM 833 CB LEU A 126 53.341 57.016 13.978 1.00 35.34 C ATOM 834 CG LEU A 126 52.343 56.437 15.019 1.00 41.60 C ATOM 835 CD1 LEU A 126 52.959 55.267 15.789 1.00 34.22 C ATOM 836 CD2 LEU A 126 51.880 57.517 16.016 1.00 40.01 C ATOM 837 N SER A 127 52.207 55.977 11.171 1.00 30.51 N ATOM 838 CA SER A 127 51.063 55.423 10.422 1.00 34.39 C ATOM 839 C SER A 127 51.421 54.140 9.696 1.00 28.30 C ATOM 840 O SER A 127 50.673 53.131 9.792 1.00 28.35 O ATOM 841 CB SER A 127 50.468 56.592 9.576 1.00 32.52 C ATOM 842 OG SER A 127 51.070 56.424 8.303 1.00 58.48 O ATOM 843 N ALA A 128 52.672 53.940 9.277 1.00 26.20 N ATOM 844 CA ALA A 128 53.177 52.667 8.770 1.00 35.59 C ATOM 845 C ALA A 128 53.302 51.669 9.919 1.00 35.87 C ATOM 846 O ALA A 128 53.045 50.455 9.728 1.00 33.59 O ATOM 847 CB ALA A 128 54.554 52.886 8.061 1.00 26.01 C ATOM 848 N ALA A 129 53.449 52.177 11.174 1.00 31.04 N ATOM 849 CA ALA A 129 53.581 51.229 12.298 1.00 32.93 C ATOM 850 C ALA A 129 52.200 50.632 12.588 1.00 37.11 C ATOM 851 O ALA A 129 51.940 49.447 12.843 1.00 29.49 O ATOM 852 CB ALA A 129 54.158 51.940 13.541 1.00 28.07 C ATOM 853 N LEU A 130 51.177 51.484 12.472 1.00 33.38 N ATOM 854 CA LEU A 130 49.803 51.054 12.682 1.00 32.64 C ATOM 855 C LEU A 130 49.294 50.112 11.584 1.00 28.69 C ATOM 856 O LEU A 130 48.530 49.198 11.914 1.00 30.49 O ATOM 857 CB LEU A 130 48.856 52.257 12.834 1.00 32.26 C ATOM 858 CG LEU A 130 49.269 53.286 13.875 1.00 34.48 C ATOM 859 CD1 LEU A 130 48.246 54.450 13.944 1.00 38.52 C ATOM 860 CD2 LEU A 130 49.404 52.666 15.254 1.00 33.74 C ATOM 861 N VAL A 131 49.668 50.297 10.326 1.00 28.89 N ATOM 862 CA VAL A 131 49.380 49.359 9.269 1.00 32.19 C ATOM 863 C VAL A 131 49.955 47.973 9.646 1.00 30.71 C ATOM 864 O VAL A 131 49.226 46.980 9.537 1.00 28.88 O ATOM 865 CB VAL A 131 50.018 49.761 7.905 1.00 33.76 C ATOM 866 CG1 VAL A 131 49.790 48.640 6.874 1.00 27.05 C ATOM 867 CG2 VAL A 131 49.465 51.088 7.436 1.00 25.28 C ATOM 868 N ALA A 132 51.175 47.942 10.227 1.00 27.19 N ATOM 869 CA ALA A 132 51.759 46.641 10.620 1.00 29.28 C ATOM 870 C ALA A 132 51.080 46.003 11.834 1.00 31.56 C ATOM 871 O ALA A 132 51.300 44.832 12.126 1.00 30.20 O ATOM 872 CB ALA A 132 53.273 46.830 10.891 1.00 26.70 C ATOM 873 N LEU A 133 50.190 46.693 12.549 1.00 26.39 N ATOM 874 CA LEU A 133 49.436 46.169 13.682 1.00 26.52 C ATOM 875 C LEU A 133 48.050 45.703 13.271 1.00 30.96 C ATOM 876 O LEU A 133 47.266 45.209 14.112 1.00 30.30 O ATOM 877 CB LEU A 133 49.266 47.258 14.781 1.00 27.49 C ATOM 878 CG LEU A 133 50.576 47.691 15.468 1.00 34.86 C ATOM 879 CD1 LEU A 133 50.405 48.720 16.579 1.00 30.71 C ATOM 880 CD2 LEU A 133 51.265 46.455 16.098 1.00 24.37 C ATOM 881 N CYS A 134 47.699 45.953 11.971 1.00 27.86 N ATOM 882 CA CYS A 134 46.348 45.463 11.570 1.00 30.21 C ATOM 883 C CYS A 134 46.445 43.960 11.297 1.00 33.88 C ATOM 884 O CYS A 134 47.547 43.454 11.046 1.00 29.61 O ATOM 885 CB CYS A 134 45.837 46.188 10.325 1.00 29.53 C ATOM 886 SG CYS A 134 45.499 47.951 10.668 1.00 30.78 S ATOM 887 N ASP A 135 45.287 43.282 11.442 1.00 28.29 N ATOM 888 CA ASP A 135 45.274 41.846 11.243 1.00 30.10 C ATOM 889 C ASP A 135 45.395 41.432 9.783 1.00 33.88 C ATOM 890 O ASP A 135 45.852 40.334 9.402 1.00 27.31 O ATOM 891 CB ASP A 135 43.991 41.299 11.866 1.00 29.89 C ATOM 892 CG ASP A 135 43.871 41.667 13.336 1.00 34.98 C ATOM 893 OD1 ASP A 135 44.867 41.411 14.084 1.00 29.77 O ATOM 894 OD2 ASP A 135 42.801 42.197 13.768 1.00 32.36 O ATOM 895 N ILE A 136 44.866 42.263 8.878 1.00 28.70 N ATOM 896 CA ILE A 136 44.715 41.901 7.454 1.00 25.90 C ATOM 897 C ILE A 136 44.965 43.172 6.678 1.00 32.90 C ATOM 898 O ILE A 136 44.502 44.269 7.116 1.00 31.21 O ATOM 899 CB ILE A 136 43.264 41.375 7.164 1.00 30.42 C ATOM 900 CG1 ILE A 136 42.985 40.033 7.849 1.00 33.04 C ATOM 901 CG2 ILE A 136 43.073 41.204 5.655 1.00 27.07 C ATOM 902 CD1 ILE A 136 41.532 39.596 7.660 1.00 34.35 C ATOM 903 N VAL A 137 45.620 43.103 5.550 1.00 28.90 N ATOM 904 CA VAL A 137 45.944 44.296 4.771 1.00 30.81 C ATOM 905 C VAL A 137 45.647 44.037 3.285 1.00 35.72 C ATOM 906 O VAL A 137 46.067 43.030 2.707 1.00 32.98 O ATOM 907 CB VAL A 137 47.430 44.703 4.880 1.00 29.40 C ATOM 908 CG1 VAL A 137 47.685 46.006 4.115 1.00 26.50 C ATOM 909 CG2 VAL A 137 47.902 44.960 6.332 1.00 23.08 C ATOM 910 N TYR A 138 44.911 44.944 2.644 1.00 29.72 N ATOM 911 CA TYR A 138 44.673 44.844 1.207 1.00 28.28 C ATOM 912 C TYR A 138 45.407 45.976 0.522 1.00 28.92 C ATOM 913 O TYR A 138 45.413 47.118 1.037 1.00 32.96 O ATOM 914 CB TYR A 138 43.182 44.866 0.896 1.00 33.13 C ATOM 915 CG TYR A 138 42.403 43.743 1.553 1.00 30.14 C ATOM 916 CD1 TYR A 138 41.384 44.019 2.463 1.00 24.77 C ATOM 917 CD2 TYR A 138 42.717 42.420 1.304 1.00 34.31 C ATOM 918 CE1 TYR A 138 40.657 43.002 3.048 1.00 30.13 C ATOM 919 CE2 TYR A 138 41.959 41.388 1.871 1.00 32.90 C ATOM 920 CZ TYR A 138 40.990 41.683 2.781 1.00 31.63 C ATOM 921 OH TYR A 138 40.314 40.681 3.417 1.00 34.18 O ATOM 922 N SER A 139 45.926 45.767 -0.692 1.00 28.76 N ATOM 923 CA SER A 139 46.684 46.849 -1.327 1.00 31.74 C ATOM 924 C SER A 139 45.930 47.269 -2.624 1.00 32.12 C ATOM 925 O SER A 139 45.318 46.470 -3.297 1.00 32.18 O ATOM 926 CB SER A 139 48.090 46.459 -1.707 1.00 26.29 C ATOM 927 OG SER A 139 48.104 45.310 -2.557 1.00 30.69 O ATOM 928 N ILE A 140 45.994 48.573 -2.897 1.00 39.75 N ATOM 929 CA ILE A 140 45.379 49.105 -4.116 1.00 39.58 C ATOM 930 C ILE A 140 46.150 48.642 -5.341 1.00 42.16 C ATOM 931 O ILE A 140 45.537 48.234 -6.353 1.00 37.24 O ATOM 932 CB ILE A 140 45.286 50.646 -4.066 1.00 41.33 C ATOM 933 CG1 ILE A 140 44.503 51.140 -5.338 1.00 46.65 C ATOM 934 CG2 ILE A 140 46.615 51.350 -3.981 1.00 30.82 C ATOM 935 CD1 ILE A 140 44.079 52.609 -5.138 1.00 38.38 C ATOM 936 N ASN A 141 47.468 48.717 -5.290 1.00 37.21 N ATOM 937 CA ASN A 141 48.303 48.297 -6.440 1.00 42.23 C ATOM 938 C ASN A 141 49.736 48.052 -5.974 1.00 43.18 C ATOM 939 O ASN A 141 50.056 48.220 -4.786 1.00 41.68 O ATOM 940 CB ASN A 141 48.241 49.314 -7.588 1.00 40.34 C ATOM 941 CG ASN A 141 48.722 50.695 -7.236 1.00 47.39 C ATOM 942 OD1 ASN A 141 49.755 50.906 -6.553 1.00 39.39 O ATOM 943 ND2 ASN A 141 47.966 51.702 -7.707 1.00 38.50 N ATOM 944 N ASP A 142 50.657 47.719 -6.855 1.00 40.84 N ATOM 945 CA ASP A 142 52.019 47.314 -6.491 1.00 33.77 C ATOM 946 C ASP A 142 52.927 48.445 -6.238 1.00 38.58 C ATOM 947 O ASP A 142 54.158 48.254 -6.247 1.00 40.62 O ATOM 948 CB ASP A 142 52.555 46.333 -7.543 1.00 39.92 C ATOM 949 CG ASP A 142 52.756 46.959 -8.920 1.00 44.70 C ATOM 950 OD1 ASP A 142 52.681 48.171 -9.135 1.00 41.37 O ATOM 951 OD2 ASP A 142 53.123 46.209 -9.849 1.00 53.37 O ATOM 952 N LYS A 143 52.375 49.679 -6.154 1.00 37.42 N ATOM 953 CA LYS A 143 53.296 50.786 -5.824 1.00 39.33 C ATOM 954 C LYS A 143 53.255 51.079 -4.325 1.00 36.20 C ATOM 955 O LYS A 143 54.043 51.948 -3.928 1.00 34.33 O ATOM 956 CB LYS A 143 53.009 52.053 -6.635 1.00 42.22 C ATOM 957 CG LYS A 143 52.985 51.732 -8.161 1.00 51.28 C ATOM 958 CD LYS A 143 52.839 52.974 -9.001 1.00 54.43 C ATOM 959 CE LYS A 143 51.492 53.659 -8.919 1.00 57.87 C ATOM 960 NZ LYS A 143 50.541 53.126 -9.915 1.00 61.48 N ATOM 961 N VAL A 144 52.406 50.396 -3.557 1.00 33.02 N ATOM 962 CA VAL A 144 52.403 50.693 -2.091 1.00 33.68 C ATOM 963 C VAL A 144 53.774 50.347 -1.486 1.00 36.06 C ATOM 964 O VAL A 144 54.490 49.479 -2.007 1.00 33.61 O ATOM 965 CB VAL A 144 51.344 49.897 -1.340 1.00 32.81 C ATOM 966 CG1 VAL A 144 49.934 50.297 -1.775 1.00 34.04 C ATOM 967 CG2 VAL A 144 51.487 48.370 -1.531 1.00 31.78 C ATOM 968 N TYR A 145 54.121 50.994 -0.370 1.00 38.23 N ATOM 969 CA TYR A 145 55.342 50.627 0.353 1.00 38.32 C ATOM 970 C TYR A 145 55.154 51.101 1.794 1.00 37.58 C ATOM 971 O TYR A 145 54.256 51.914 2.031 1.00 33.49 O ATOM 972 CB TYR A 145 56.667 51.131 -0.221 1.00 33.46 C ATOM 973 CG TYR A 145 56.803 52.640 -0.301 1.00 37.99 C ATOM 974 CD1 TYR A 145 56.521 53.327 -1.489 1.00 38.69 C ATOM 975 CD2 TYR A 145 57.209 53.365 0.814 1.00 39.13 C ATOM 976 CE1 TYR A 145 56.623 54.717 -1.548 1.00 31.89 C ATOM 977 CE2 TYR A 145 57.357 54.729 0.782 1.00 44.18 C ATOM 978 CZ TYR A 145 56.996 55.402 -0.411 1.00 41.43 C ATOM 979 OH TYR A 145 57.162 56.741 -0.409 1.00 38.21 O ATOM 980 N LEU A 146 55.967 50.539 2.695 1.00 31.53 N ATOM 981 CA LEU A 146 55.882 51.025 4.097 1.00 36.30 C ATOM 982 C LEU A 146 57.278 51.587 4.396 1.00 36.10 C ATOM 983 O LEU A 146 58.258 50.901 4.064 1.00 37.19 O ATOM 984 CB LEU A 146 55.599 49.880 5.100 1.00 32.08 C ATOM 985 CG LEU A 146 54.259 49.142 4.825 1.00 34.36 C ATOM 986 CD1 LEU A 146 54.091 47.978 5.823 1.00 30.71 C ATOM 987 CD2 LEU A 146 53.113 50.143 4.935 1.00 28.88 C ATOM 988 N LEU A 147 57.368 52.787 4.974 1.00 36.77 N ATOM 989 CA LEU A 147 58.721 53.281 5.275 1.00 35.10 C ATOM 990 C LEU A 147 58.789 53.678 6.735 1.00 29.79 C ATOM 991 O LEU A 147 57.916 54.367 7.279 1.00 32.72 O ATOM 992 CB LEU A 147 59.006 54.527 4.364 1.00 34.75 C ATOM 993 CG LEU A 147 60.370 55.239 4.633 1.00 40.74 C ATOM 994 CD1 LEU A 147 61.523 54.322 4.250 1.00 39.65 C ATOM 995 CD2 LEU A 147 60.484 56.529 3.787 1.00 43.70 C ATOM 996 N TYR A 148 59.875 53.269 7.411 1.00 33.56 N ATOM 997 CA TYR A 148 60.095 53.553 8.826 1.00 34.67 C ATOM 998 C TYR A 148 61.485 54.242 8.864 1.00 37.16 C ATOM 999 O TYR A 148 62.521 53.594 8.960 1.00 36.75 O ATOM 1000 CB TYR A 148 60.133 52.281 9.685 1.00 28.78 C ATOM 1001 CG TYR A 148 58.940 51.369 9.487 1.00 34.56 C ATOM 1002 CD1 TYR A 148 58.846 50.514 8.401 1.00 30.75 C ATOM 1003 CD2 TYR A 148 57.801 51.587 10.305 1.00 28.55 C ATOM 1004 CE1 TYR A 148 57.690 49.740 8.183 1.00 29.99 C ATOM 1005 CE2 TYR A 148 56.662 50.836 10.071 1.00 32.41 C ATOM 1006 CZ TYR A 148 56.619 49.891 9.060 1.00 28.80 C ATOM 1007 OH TYR A 148 55.436 49.225 8.842 1.00 28.66 O ATOM 1008 N PRO A 149 61.479 55.563 8.788 1.00 33.24 N ATOM 1009 CA PRO A 149 62.734 56.320 8.670 1.00 35.14 C ATOM 1010 C PRO A 149 63.258 56.744 10.012 1.00 37.19 C ATOM 1011 O PRO A 149 63.940 57.786 10.133 1.00 39.46 O ATOM 1012 CB PRO A 149 62.272 57.539 7.817 1.00 34.53 C ATOM 1013 CG PRO A 149 60.961 57.864 8.544 1.00 37.57 C ATOM 1014 CD PRO A 149 60.310 56.457 8.773 1.00 34.22 C ATOM 1015 N PHE A 150 63.291 55.784 10.970 1.00 34.80 N ATOM 1016 CA PHE A 150 63.767 56.107 12.314 1.00 38.46 C ATOM 1017 C PHE A 150 65.240 56.516 12.267 1.00 36.27 C ATOM 1018 O PHE A 150 65.614 57.448 12.974 1.00 31.69 O ATOM 1019 CB PHE A 150 63.586 54.936 13.323 1.00 35.63 C ATOM 1020 CG PHE A 150 62.162 54.419 13.293 1.00 40.75 C ATOM 1021 CD1 PHE A 150 61.924 53.051 13.234 1.00 38.01 C ATOM 1022 CD2 PHE A 150 61.092 55.322 13.286 1.00 32.84 C ATOM 1023 CE1 PHE A 150 60.622 52.543 13.240 1.00 37.19 C ATOM 1024 CE2 PHE A 150 59.787 54.824 13.269 1.00 37.74 C ATOM 1025 CZ PHE A 150 59.557 53.448 13.258 1.00 37.56 C ATOM 1026 N ALA A 151 66.052 55.809 11.488 1.00 34.19 N ATOM 1027 CA ALA A 151 67.481 56.102 11.526 1.00 40.49 C ATOM 1028 C ALA A 151 67.797 57.513 10.952 1.00 44.61 C ATOM 1029 O ALA A 151 68.833 58.061 11.309 1.00 40.03 O ATOM 1030 CB ALA A 151 68.313 55.085 10.803 1.00 31.26 C ATOM 1031 N ASN A 152 66.978 58.024 10.080 1.00 38.71 N ATOM 1032 CA ASN A 152 67.061 59.307 9.452 1.00 45.38 C ATOM 1033 C ASN A 152 66.495 60.446 10.316 1.00 49.96 C ATOM 1034 O ASN A 152 66.834 61.616 10.073 1.00 48.42 O ATOM 1035 CB ASN A 152 66.366 59.311 8.077 1.00 40.45 C ATOM 1036 CG ASN A 152 67.084 60.272 7.102 1.00 60.17 C ATOM 1037 OD1 ASN A 152 68.275 60.624 7.207 1.00 48.37 O ATOM 1038 ND2 ASN A 152 66.348 60.656 6.071 1.00 56.90 N ATOM 1039 N LEU A 153 65.765 60.114 11.385 1.00 41.65 N ATOM 1040 CA LEU A 153 65.231 61.130 12.271 1.00 40.77 C ATOM 1041 C LEU A 153 65.918 61.136 13.623 1.00 38.09 C ATOM 1042 O LEU A 153 65.539 61.904 14.487 1.00 41.88 O ATOM 1043 CB LEU A 153 63.705 61.001 12.458 1.00 42.04 C ATOM 1044 CG LEU A 153 62.908 61.191 11.139 1.00 50.40 C ATOM 1045 CD1 LEU A 153 61.455 60.809 11.344 1.00 53.99 C ATOM 1046 CD2 LEU A 153 63.039 62.610 10.615 1.00 49.51 C ATOM 1047 N GLY A 154 66.934 60.321 13.812 1.00 36.38 N ATOM 1048 CA GLY A 154 67.665 60.196 15.078 1.00 38.21 C ATOM 1049 C GLY A 154 66.774 59.556 16.134 1.00 44.45 C ATOM 1050 O GLY A 154 66.864 59.847 17.316 1.00 42.76 O ATOM 1051 N LEU A 155 65.885 58.628 15.687 1.00 42.94 N ATOM 1052 CA LEU A 155 65.012 57.950 16.621 1.00 37.20 C ATOM 1053 C LEU A 155 65.165 56.443 16.565 1.00 39.49 C ATOM 1054 O LEU A 155 66.112 55.915 15.935 1.00 38.07 O ATOM 1055 CB LEU A 155 63.580 58.395 16.357 1.00 40.27 C ATOM 1056 CG LEU A 155 63.225 59.882 16.726 1.00 43.43 C ATOM 1057 CD1 LEU A 155 61.819 60.134 16.222 1.00 42.14 C ATOM 1058 CD2 LEU A 155 63.289 60.075 18.229 1.00 39.05 C ATOM 1059 N ILE A 156 64.321 55.731 17.360 1.00 33.19 N ATOM 1060 CA ILE A 156 64.420 54.254 17.297 1.00 36.74 C ATOM 1061 C ILE A 156 63.057 53.670 16.983 1.00 35.49 C ATOM 1062 O ILE A 156 62.185 54.363 16.443 1.00 32.74 O ATOM 1063 CB ILE A 156 65.020 53.637 18.573 1.00 36.24 C ATOM 1064 CG1 ILE A 156 64.165 54.014 19.767 1.00 38.98 C ATOM 1065 CG2 ILE A 156 66.501 54.049 18.729 1.00 31.47 C ATOM 1066 CD1 ILE A 156 64.482 53.466 21.118 1.00 43.94 C ATOM 1067 N THR A 157 62.890 52.337 17.085 1.00 37.43 N ATOM 1068 CA THR A 157 61.591 51.777 16.688 1.00 29.91 C ATOM 1069 C THR A 157 60.453 52.372 17.505 1.00 31.73 C ATOM 1070 O THR A 157 60.568 52.644 18.708 1.00 30.77 O ATOM 1071 CB THR A 157 61.579 50.241 16.880 1.00 37.37 C ATOM 1072 OG1 THR A 157 62.249 49.943 18.128 1.00 34.80 O ATOM 1073 CG2 THR A 157 62.226 49.545 15.693 1.00 25.08 C ATOM 1074 N GLU A 158 59.290 52.506 16.856 1.00 29.20 N ATOM 1075 CA GLU A 158 58.136 52.973 17.629 1.00 35.75 C ATOM 1076 C GLU A 158 56.907 52.221 17.140 1.00 29.35 C ATOM 1077 O GLU A 158 56.935 51.550 16.111 1.00 31.06 O ATOM 1078 CB GLU A 158 57.964 54.491 17.470 1.00 41.31 C ATOM 1079 CG GLU A 158 57.388 54.886 16.127 1.00 43.99 C ATOM 1080 CD GLU A 158 57.436 56.431 15.947 1.00 55.45 C ATOM 1081 OE1 GLU A 158 56.927 56.857 14.900 1.00 57.19 O ATOM 1082 OE2 GLU A 158 57.972 57.165 16.766 1.00 56.97 O ATOM 1083 N GLY A 159 55.784 52.454 17.824 1.00 29.88 N ATOM 1084 CA GLY A 159 54.531 51.891 17.357 1.00 30.63 C ATOM 1085 C GLY A 159 54.505 50.374 17.455 1.00 35.22 C ATOM 1086 O GLY A 159 53.749 49.778 16.662 1.00 29.82 O ATOM 1087 N GLY A 160 55.435 49.758 18.245 1.00 30.14 N ATOM 1088 CA GLY A 160 55.364 48.263 18.333 1.00 30.73 C ATOM 1089 C GLY A 160 56.084 47.620 17.153 1.00 29.25 C ATOM 1090 O GLY A 160 56.149 46.381 17.126 1.00 29.07 O ATOM 1091 N THR A 161 56.833 48.392 16.355 1.00 24.01 N ATOM 1092 CA THR A 161 57.538 47.842 15.167 1.00 29.76 C ATOM 1093 C THR A 161 58.737 46.984 15.561 1.00 28.14 C ATOM 1094 O THR A 161 59.128 46.089 14.833 1.00 26.08 O ATOM 1095 CB THR A 161 58.115 48.950 14.234 1.00 29.00 C ATOM 1096 OG1 THR A 161 58.722 49.928 15.087 1.00 27.37 O ATOM 1097 CG2 THR A 161 56.931 49.623 13.473 1.00 26.58 C ATOM 1098 N THR A 162 59.211 47.142 16.800 1.00 29.04 N ATOM 1099 CA THR A 162 60.270 46.275 17.342 1.00 29.69 C ATOM 1100 C THR A 162 59.769 44.829 17.189 1.00 30.02 C ATOM 1101 O THR A 162 60.525 43.885 17.021 1.00 27.88 O ATOM 1102 CB THR A 162 60.516 46.570 18.850 1.00 29.21 C ATOM 1103 OG1 THR A 162 60.839 47.927 19.088 1.00 28.09 O ATOM 1104 CG2 THR A 162 61.592 45.628 19.424 1.00 29.36 C ATOM 1105 N VAL A 163 58.500 44.580 17.526 1.00 29.12 N ATOM 1106 CA VAL A 163 57.953 43.228 17.388 1.00 26.12 C ATOM 1107 C VAL A 163 57.280 42.961 16.048 1.00 28.44 C ATOM 1108 O VAL A 163 57.509 41.920 15.380 1.00 26.19 O ATOM 1109 CB VAL A 163 56.895 43.046 18.550 1.00 26.19 C ATOM 1110 CG1 VAL A 163 56.139 41.739 18.340 1.00 26.97 C ATOM 1111 CG2 VAL A 163 57.737 42.986 19.872 1.00 23.86 C ATOM 1112 N SER A 164 56.460 43.860 15.532 1.00 28.50 N ATOM 1113 CA SER A 164 55.639 43.622 14.322 1.00 27.88 C ATOM 1114 C SER A 164 56.434 43.467 13.027 1.00 28.02 C ATOM 1115 O SER A 164 56.141 42.610 12.210 1.00 29.61 O ATOM 1116 CB SER A 164 54.653 44.810 14.136 1.00 27.84 C ATOM 1117 OG SER A 164 55.355 45.975 13.703 1.00 25.30 O ATOM 1118 N LEU A 165 57.604 44.117 12.921 1.00 23.63 N ATOM 1119 CA LEU A 165 58.362 44.003 11.692 1.00 26.89 C ATOM 1120 C LEU A 165 59.066 42.679 11.525 1.00 24.73 C ATOM 1121 O LEU A 165 58.829 41.994 10.500 1.00 27.75 O ATOM 1122 CB LEU A 165 59.184 45.236 11.426 1.00 24.42 C ATOM 1123 CG LEU A 165 58.456 46.577 11.301 1.00 31.52 C ATOM 1124 CD1 LEU A 165 59.453 47.680 11.064 1.00 26.49 C ATOM 1125 CD2 LEU A 165 57.365 46.538 10.212 1.00 29.90 C ATOM 1126 N PRO A 166 59.777 42.173 12.508 1.00 25.70 N ATOM 1127 CA PRO A 166 60.388 40.856 12.426 1.00 30.42 C ATOM 1128 C PRO A 166 59.303 39.781 12.377 1.00 28.86 C ATOM 1129 O PRO A 166 59.438 38.818 11.606 1.00 27.86 O ATOM 1130 CB PRO A 166 61.216 40.674 13.729 1.00 26.35 C ATOM 1131 CG PRO A 166 61.425 42.110 14.195 1.00 32.44 C ATOM 1132 CD PRO A 166 60.185 42.917 13.768 1.00 26.21 C ATOM 1133 N LEU A 167 58.184 39.989 13.016 1.00 27.10 N ATOM 1134 CA LEU A 167 57.061 39.060 12.978 1.00 27.84 C ATOM 1135 C LEU A 167 56.538 38.908 11.543 1.00 27.08 C ATOM 1136 O LEU A 167 56.025 37.863 11.173 1.00 28.14 O ATOM 1137 CB LEU A 167 55.893 39.576 13.818 1.00 27.97 C ATOM 1138 CG LEU A 167 54.819 38.744 14.471 1.00 42.88 C ATOM 1139 CD1 LEU A 167 53.428 39.325 14.455 1.00 32.42 C ATOM 1140 CD2 LEU A 167 54.838 37.263 14.276 1.00 30.14 C ATOM 1141 N LYS A 168 56.316 40.095 10.906 1.00 25.19 N ATOM 1142 CA LYS A 168 55.627 39.996 9.603 1.00 30.98 C ATOM 1143 C LYS A 168 56.541 40.007 8.396 1.00 32.79 C ATOM 1144 O LYS A 168 56.138 39.677 7.253 1.00 26.66 O ATOM 1145 CB LYS A 168 54.591 41.167 9.535 1.00 28.01 C ATOM 1146 CG LYS A 168 53.599 40.953 10.707 1.00 31.15 C ATOM 1147 CD LYS A 168 52.363 41.792 10.533 1.00 32.31 C ATOM 1148 CE LYS A 168 51.482 41.613 11.793 1.00 32.47 C ATOM 1149 NZ LYS A 168 50.183 42.271 11.517 1.00 27.14 N ATOM 1150 N PHE A 169 57.778 40.465 8.562 1.00 26.20 N ATOM 1151 CA PHE A 169 58.695 40.484 7.408 1.00 26.46 C ATOM 1152 C PHE A 169 59.943 39.669 7.654 1.00 25.79 C ATOM 1153 O PHE A 169 60.777 39.600 6.714 1.00 30.97 O ATOM 1154 CB PHE A 169 59.102 41.942 7.089 1.00 27.32 C ATOM 1155 CG PHE A 169 57.910 42.785 6.701 1.00 30.59 C ATOM 1156 CD1 PHE A 169 57.367 43.695 7.599 1.00 26.85 C ATOM 1157 CD2 PHE A 169 57.350 42.613 5.435 1.00 29.25 C ATOM 1158 CE1 PHE A 169 56.268 44.485 7.197 1.00 29.70 C ATOM 1159 CE2 PHE A 169 56.284 43.395 5.035 1.00 28.56 C ATOM 1160 CZ PHE A 169 55.730 44.308 5.947 1.00 30.07 C ATOM 1161 N GLY A 170 60.102 39.079 8.852 1.00 27.20 N ATOM 1162 CA GLY A 170 61.367 38.289 9.037 1.00 28.61 C ATOM 1163 C GLY A 170 62.465 39.176 9.605 1.00 31.85 C ATOM 1164 O GLY A 170 62.467 40.423 9.447 1.00 29.00 O ATOM 1165 N THR A 171 63.386 38.620 10.384 1.00 25.44 N ATOM 1166 CA THR A 171 64.392 39.390 11.081 1.00 26.12 C ATOM 1167 C THR A 171 65.450 39.942 10.112 1.00 23.72 C ATOM 1168 O THR A 171 65.650 41.178 10.188 1.00 26.30 O ATOM 1169 CB THR A 171 65.140 38.581 12.204 1.00 31.55 C ATOM 1170 OG1 THR A 171 66.064 37.693 11.581 1.00 40.65 O ATOM 1171 CG2 THR A 171 64.186 37.613 12.881 1.00 33.57 C ATOM 1172 N ASN A 172 66.022 39.202 9.175 1.00 26.05 N ATOM 1173 CA ASN A 172 67.066 39.832 8.297 1.00 26.50 C ATOM 1174 C ASN A 172 66.568 40.969 7.428 1.00 33.92 C ATOM 1175 O ASN A 172 67.237 41.989 7.135 1.00 28.17 O ATOM 1176 CB ASN A 172 67.663 38.762 7.333 1.00 26.03 C ATOM 1177 CG ASN A 172 68.557 37.782 8.154 1.00 31.60 C ATOM 1178 OD1 ASN A 172 68.517 37.787 9.380 1.00 28.73 O ATOM 1179 ND2 ASN A 172 69.381 36.999 7.470 1.00 27.44 N ATOM 1180 N THR A 173 65.376 40.826 6.822 1.00 29.13 N ATOM 1181 CA THR A 173 64.779 41.857 6.006 1.00 28.77 C ATOM 1182 C THR A 173 64.509 43.104 6.881 1.00 31.67 C ATOM 1183 O THR A 173 64.719 44.231 6.433 1.00 31.18 O ATOM 1184 CB THR A 173 63.394 41.318 5.482 1.00 29.25 C ATOM 1185 OG1 THR A 173 63.660 40.309 4.491 1.00 28.41 O ATOM 1186 CG2 THR A 173 62.563 42.366 4.781 1.00 25.90 C ATOM 1187 N THR A 174 64.031 42.894 8.121 1.00 26.54 N ATOM 1188 CA THR A 174 63.747 44.027 9.010 1.00 27.35 C ATOM 1189 C THR A 174 65.029 44.828 9.290 1.00 28.76 C ATOM 1190 O THR A 174 65.039 46.045 9.281 1.00 31.96 O ATOM 1191 CB THR A 174 63.140 43.533 10.348 1.00 30.41 C ATOM 1192 OG1 THR A 174 61.813 43.146 10.030 1.00 28.85 O ATOM 1193 CG2 THR A 174 63.156 44.637 11.445 1.00 22.92 C ATOM 1194 N TYR A 175 66.133 44.156 9.551 1.00 29.84 N ATOM 1195 CA TYR A 175 67.417 44.855 9.759 1.00 34.37 C ATOM 1196 C TYR A 175 67.832 45.624 8.493 1.00 33.18 C ATOM 1197 O TYR A 175 68.135 46.803 8.637 1.00 32.39 O ATOM 1198 CB TYR A 175 68.541 43.888 10.146 1.00 25.56 C ATOM 1199 CG TYR A 175 68.542 43.687 11.676 1.00 32.50 C ATOM 1200 CD1 TYR A 175 67.773 42.663 12.254 1.00 29.40 C ATOM 1201 CD2 TYR A 175 69.370 44.456 12.464 1.00 28.99 C ATOM 1202 CE1 TYR A 175 67.906 42.405 13.617 1.00 32.87 C ATOM 1203 CE2 TYR A 175 69.455 44.243 13.852 1.00 29.59 C ATOM 1204 CZ TYR A 175 68.760 43.205 14.398 1.00 32.14 C ATOM 1205 OH TYR A 175 68.768 43.018 15.770 1.00 34.48 O ATOM 1206 N GLU A 176 67.820 44.988 7.322 1.00 30.28 N ATOM 1207 CA GLU A 176 68.131 45.781 6.106 1.00 34.01 C ATOM 1208 C GLU A 176 67.302 47.031 6.025 1.00 34.37 C ATOM 1209 O GLU A 176 67.806 48.183 5.814 1.00 34.15 O ATOM 1210 CB GLU A 176 68.016 44.909 4.844 1.00 27.32 C ATOM 1211 CG GLU A 176 68.125 45.739 3.500 1.00 32.64 C ATOM 1212 CD GLU A 176 69.622 46.079 3.273 1.00 43.40 C ATOM 1213 OE1 GLU A 176 70.481 45.385 3.859 1.00 36.84 O ATOM 1214 OE2 GLU A 176 70.009 47.041 2.590 1.00 38.60 O ATOM 1215 N CYS A 177 65.966 46.934 6.211 1.00 30.85 N ATOM 1216 CA CYS A 177 65.155 48.140 6.000 1.00 31.37 C ATOM 1217 C CYS A 177 65.386 49.202 7.065 1.00 34.84 C ATOM 1218 O CYS A 177 65.297 50.408 6.782 1.00 32.97 O ATOM 1219 CB CYS A 177 63.646 47.795 5.871 1.00 33.37 C ATOM 1220 SG CYS A 177 63.240 46.778 4.432 1.00 30.94 S ATOM 1221 N LEU A 178 65.378 48.782 8.340 1.00 31.73 N ATOM 1222 CA LEU A 178 65.425 49.713 9.453 1.00 27.03 C ATOM 1223 C LEU A 178 66.826 50.327 9.570 1.00 31.60 C ATOM 1224 O LEU A 178 66.914 51.506 9.833 1.00 32.14 O ATOM 1225 CB LEU A 178 65.110 49.054 10.808 1.00 25.36 C ATOM 1226 CG LEU A 178 63.634 48.602 10.965 1.00 33.93 C ATOM 1227 CD1 LEU A 178 63.393 48.154 12.408 1.00 31.08 C ATOM 1228 CD2 LEU A 178 62.655 49.724 10.562 1.00 34.38 C ATOM 1229 N MET A 179 67.853 49.503 9.453 1.00 30.39 N ATOM 1230 CA MET A 179 69.204 50.029 9.661 1.00 34.06 C ATOM 1231 C MET A 179 69.558 51.087 8.577 1.00 39.76 C ATOM 1232 O MET A 179 70.248 52.062 8.906 1.00 36.37 O ATOM 1233 CB MET A 179 70.241 48.951 9.683 1.00 32.35 C ATOM 1234 CG MET A 179 70.232 47.890 10.786 1.00 33.03 C ATOM 1235 SD MET A 179 70.238 48.530 12.448 1.00 34.27 S ATOM 1236 CE MET A 179 68.561 48.291 13.006 1.00 32.41 C ATOM 1237 N PHE A 180 69.096 50.909 7.346 1.00 35.31 N ATOM 1238 CA PHE A 180 69.466 51.728 6.212 1.00 35.11 C ATOM 1239 C PHE A 180 68.324 52.632 5.741 1.00 35.32 C ATOM 1240 O PHE A 180 68.383 53.218 4.651 1.00 36.56 O ATOM 1241 CB PHE A 180 69.981 50.829 5.099 1.00 29.53 C ATOM 1242 CG PHE A 180 71.211 50.019 5.491 1.00 32.80 C ATOM 1243 CD1 PHE A 180 71.229 48.648 5.418 1.00 34.30 C ATOM 1244 CD2 PHE A 180 72.330 50.665 5.990 1.00 36.11 C ATOM 1245 CE1 PHE A 180 72.341 47.912 5.844 1.00 35.44 C ATOM 1246 CE2 PHE A 180 73.458 49.950 6.400 1.00 35.43 C ATOM 1247 CZ PHE A 180 73.463 48.577 6.288 1.00 41.52 C ATOM 1248 N ASN A 181 67.294 52.828 6.540 1.00 32.51 N ATOM 1249 CA ASN A 181 66.152 53.665 6.138 1.00 34.53 C ATOM 1250 C ASN A 181 65.650 53.345 4.736 1.00 38.58 C ATOM 1251 O ASN A 181 65.451 54.194 3.857 1.00 32.91 O ATOM 1252 CB ASN A 181 66.445 55.163 6.380 1.00 44.45 C ATOM 1253 CG ASN A 181 65.277 56.030 5.890 1.00 43.88 C ATOM 1254 OD1 ASN A 181 64.116 55.630 5.999 1.00 52.65 O ATOM 1255 ND2 ASN A 181 65.571 57.087 5.170 1.00 48.75 N ATOM 1256 N LYS A 182 65.414 52.042 4.431 1.00 34.45 N ATOM 1257 CA LYS A 182 64.895 51.597 3.145 1.00 30.29 C ATOM 1258 C LYS A 182 63.450 51.080 3.324 1.00 35.80 C ATOM 1259 O LYS A 182 63.060 50.627 4.405 1.00 38.75 O ATOM 1260 CB LYS A 182 65.739 50.415 2.583 1.00 32.05 C ATOM 1261 CG LYS A 182 67.127 50.900 2.128 1.00 37.41 C ATOM 1262 CD LYS A 182 68.066 49.754 1.830 1.00 42.76 C ATOM 1263 CE LYS A 182 67.572 48.884 0.665 1.00 46.12 C ATOM 1264 NZ LYS A 182 68.497 47.695 0.574 1.00 36.01 N ATOM 1265 N PRO A 183 62.608 51.308 2.306 1.00 34.71 N ATOM 1266 CA PRO A 183 61.239 50.929 2.357 1.00 31.48 C ATOM 1267 C PRO A 183 60.988 49.423 2.320 1.00 33.58 C ATOM 1268 O PRO A 183 61.745 48.666 1.744 1.00 31.43 O ATOM 1269 CB PRO A 183 60.596 51.668 1.131 1.00 32.54 C ATOM 1270 CG PRO A 183 61.743 51.767 0.146 1.00 36.49 C ATOM 1271 CD PRO A 183 62.988 52.053 1.034 1.00 30.70 C ATOM 1272 N PHE A 184 59.890 48.983 2.968 1.00 31.54 N ATOM 1273 CA PHE A 184 59.353 47.619 2.750 1.00 32.76 C ATOM 1274 C PHE A 184 58.385 47.813 1.552 1.00 33.93 C ATOM 1275 O PHE A 184 57.277 48.372 1.668 1.00 32.93 O ATOM 1276 CB PHE A 184 58.528 47.162 3.960 1.00 28.68 C ATOM 1277 CG PHE A 184 59.319 46.914 5.230 1.00 30.81 C ATOM 1278 CD1 PHE A 184 59.787 47.929 6.017 1.00 32.99 C ATOM 1279 CD2 PHE A 184 59.625 45.598 5.557 1.00 25.54 C ATOM 1280 CE1 PHE A 184 60.508 47.668 7.224 1.00 34.48 C ATOM 1281 CE2 PHE A 184 60.407 45.337 6.692 1.00 29.19 C ATOM 1282 CZ PHE A 184 60.806 46.337 7.511 1.00 30.46 C ATOM 1283 N LYS A 185 58.817 47.354 0.402 1.00 34.57 N ATOM 1284 CA LYS A 185 58.084 47.537 -0.828 1.00 37.93 C ATOM 1285 C LYS A 185 57.106 46.419 -1.056 1.00 37.65 C ATOM 1286 O LYS A 185 57.153 45.336 -0.450 1.00 33.89 O ATOM 1287 CB LYS A 185 59.083 47.640 -1.993 1.00 38.10 C ATOM 1288 CG LYS A 185 59.935 48.902 -1.977 1.00 44.13 C ATOM 1289 CD LYS A 185 61.029 48.717 -3.047 1.00 47.66 C ATOM 1290 CE LYS A 185 61.670 50.054 -3.398 1.00 55.48 C ATOM 1291 NZ LYS A 185 62.743 49.794 -4.449 1.00 65.34 N ATOM 1292 N TYR A 186 56.334 46.610 -2.129 1.00 33.88 N ATOM 1293 CA TYR A 186 55.328 45.623 -2.480 1.00 32.61 C ATOM 1294 C TYR A 186 55.874 44.202 -2.616 1.00 34.25 C ATOM 1295 O TYR A 186 55.217 43.248 -2.158 1.00 35.42 O ATOM 1296 CB TYR A 186 54.704 46.103 -3.839 1.00 32.74 C ATOM 1297 CG TYR A 186 53.691 45.086 -4.308 1.00 37.02 C ATOM 1298 CD1 TYR A 186 52.453 45.105 -3.654 1.00 40.06 C ATOM 1299 CD2 TYR A 186 53.928 44.235 -5.392 1.00 33.69 C ATOM 1300 CE1 TYR A 186 51.437 44.241 -4.054 1.00 36.20 C ATOM 1301 CE2 TYR A 186 52.897 43.352 -5.780 1.00 38.12 C ATOM 1302 CZ TYR A 186 51.678 43.402 -5.133 1.00 43.21 C ATOM 1303 OH TYR A 186 50.630 42.572 -5.485 1.00 43.70 O ATOM 1304 N ASP A 187 56.950 43.998 -3.366 1.00 30.20 N ATOM 1305 CA ASP A 187 57.514 42.667 -3.606 1.00 39.06 C ATOM 1306 C ASP A 187 57.885 41.944 -2.299 1.00 33.97 C ATOM 1307 O ASP A 187 57.435 40.814 -2.045 1.00 36.56 O ATOM 1308 CB AASP A 187 58.751 42.773 -4.507 0.50 33.81 C ATOM 1309 CB BASP A 187 58.704 42.703 -4.566 0.50 39.97 C ATOM 1310 CG AASP A 187 59.883 43.634 -4.023 0.50 40.92 C ATOM 1311 CG BASP A 187 58.427 43.015 -6.008 0.50 48.73 C ATOM 1312 OD1AASP A 187 59.826 44.453 -3.083 0.50 38.13 O ATOM 1313 OD1BASP A 187 57.498 43.776 -6.370 0.50 55.71 O ATOM 1314 OD2AASP A 187 60.983 43.498 -4.640 0.50 47.10 O ATOM 1315 OD2BASP A 187 59.149 42.510 -6.918 0.50 57.67 O ATOM 1316 N ILE A 188 58.461 42.671 -1.359 1.00 37.91 N ATOM 1317 CA ILE A 188 58.748 42.185 0.007 1.00 38.45 C ATOM 1318 C ILE A 188 57.499 41.888 0.788 1.00 31.87 C ATOM 1319 O ILE A 188 57.316 40.863 1.471 1.00 32.43 O ATOM 1320 CB ILE A 188 59.580 43.322 0.695 1.00 35.41 C ATOM 1321 CG1 ILE A 188 61.016 43.216 0.123 1.00 38.93 C ATOM 1322 CG2 ILE A 188 59.580 43.224 2.206 1.00 35.49 C ATOM 1323 CD1 ILE A 188 61.710 41.909 0.471 1.00 49.14 C ATOM 1324 N MET A 189 56.528 42.791 0.665 1.00 26.64 N ATOM 1325 CA MET A 189 55.224 42.521 1.298 1.00 31.16 C ATOM 1326 C MET A 189 54.564 41.265 0.747 1.00 34.13 C ATOM 1327 O MET A 189 54.110 40.408 1.561 1.00 34.62 O ATOM 1328 CB MET A 189 54.274 43.719 1.154 1.00 32.13 C ATOM 1329 CG MET A 189 54.705 44.933 1.978 1.00 34.70 C ATOM 1330 SD MET A 189 53.481 46.324 1.673 1.00 45.64 S ATOM 1331 CE MET A 189 54.577 47.523 1.103 1.00 40.14 C ATOM 1332 N CYS A 190 54.670 40.968 -0.559 1.00 32.46 N ATOM 1333 CA CYS A 190 53.996 39.774 -1.093 1.00 35.76 C ATOM 1334 C CYS A 190 54.770 38.514 -0.760 1.00 36.81 C ATOM 1335 O CYS A 190 54.198 37.461 -0.484 1.00 40.49 O ATOM 1336 CB CYS A 190 53.837 39.832 -2.658 1.00 41.10 C ATOM 1337 SG CYS A 190 52.758 41.217 -3.131 1.00 43.40 S ATOM 1338 N GLU A 191 56.106 38.654 -0.735 1.00 31.40 N ATOM 1339 CA GLU A 191 56.959 37.524 -0.422 1.00 39.18 C ATOM 1340 C GLU A 191 56.753 37.036 1.012 1.00 42.56 C ATOM 1341 O GLU A 191 57.091 35.893 1.297 1.00 39.09 O ATOM 1342 CB GLU A 191 58.411 38.000 -0.648 1.00 45.28 C ATOM 1343 CG GLU A 191 58.618 38.169 -2.169 1.00 61.79 C ATOM 1344 CD GLU A 191 59.901 38.839 -2.585 1.00 68.25 C ATOM 1345 OE1 GLU A 191 60.854 38.997 -1.809 1.00 69.81 O ATOM 1346 OE2 GLU A 191 59.979 39.187 -3.795 1.00 75.27 O ATOM 1347 N ASN A 192 56.294 37.916 1.913 1.00 33.30 N ATOM 1348 CA ASN A 192 55.870 37.567 3.246 1.00 35.74 C ATOM 1349 C ASN A 192 54.383 37.442 3.490 1.00 31.94 C ATOM 1350 O ASN A 192 54.066 37.224 4.693 1.00 30.91 O ATOM 1351 CB ASN A 192 56.419 38.656 4.255 1.00 30.66 C ATOM 1352 CG ASN A 192 57.932 38.573 4.301 1.00 35.58 C ATOM 1353 OD1 ASN A 192 58.462 37.738 5.024 1.00 29.69 O ATOM 1354 ND2 ASN A 192 58.723 39.380 3.548 1.00 31.65 N ATOM 1355 N GLY A 193 53.459 37.507 2.522 1.00 30.21 N ATOM 1356 CA GLY A 193 52.025 37.264 2.838 1.00 33.75 C ATOM 1357 C GLY A 193 51.407 38.358 3.663 1.00 29.82 C ATOM 1358 O GLY A 193 50.505 38.070 4.440 1.00 35.99 O ATOM 1359 N PHE A 194 52.075 39.519 3.621 1.00 26.34 N ATOM 1360 CA PHE A 194 51.642 40.682 4.402 1.00 31.37 C ATOM 1361 C PHE A 194 50.333 41.232 3.771 1.00 30.12 C ATOM 1362 O PHE A 194 49.459 41.690 4.494 1.00 33.45 O ATOM 1363 CB PHE A 194 52.702 41.806 4.397 1.00 28.09 C ATOM 1364 CG PHE A 194 52.347 43.020 5.229 1.00 30.59 C ATOM 1365 CD1 PHE A 194 52.494 42.992 6.594 1.00 25.88 C ATOM 1366 CD2 PHE A 194 51.889 44.204 4.612 1.00 31.44 C ATOM 1367 CE1 PHE A 194 52.203 44.121 7.395 1.00 28.36 C ATOM 1368 CE2 PHE A 194 51.571 45.335 5.377 1.00 32.62 C ATOM 1369 CZ PHE A 194 51.762 45.299 6.760 1.00 30.01 C ATOM 1370 N ILE A 195 50.293 41.157 2.440 1.00 29.07 N ATOM 1371 CA ILE A 195 49.098 41.633 1.697 1.00 33.43 C ATOM 1372 C ILE A 195 48.237 40.425 1.379 1.00 36.04 C ATOM 1373 O ILE A 195 48.771 39.482 0.781 1.00 34.93 O ATOM 1374 CB ILE A 195 49.507 42.397 0.433 1.00 34.74 C ATOM 1375 CG1 ILE A 195 50.114 43.758 0.900 1.00 33.51 C ATOM 1376 CG2 ILE A 195 48.349 42.626 -0.562 1.00 30.16 C ATOM 1377 CD1 ILE A 195 50.980 44.272 -0.265 1.00 46.65 C ATOM 1378 N SER A 196 46.981 40.420 1.808 1.00 30.52 N ATOM 1379 CA SER A 196 46.105 39.293 1.475 1.00 38.99 C ATOM 1380 C SER A 196 45.581 39.363 0.032 1.00 37.32 C ATOM 1381 O SER A 196 45.286 38.312 -0.533 1.00 40.59 O ATOM 1382 CB SER A 196 44.860 39.229 2.392 1.00 35.24 C ATOM 1383 OG SER A 196 45.353 38.801 3.699 1.00 64.02 O ATOM 1384 N LYS A 197 45.348 40.546 -0.473 1.00 33.24 N ATOM 1385 CA LYS A 197 44.936 40.703 -1.870 1.00 36.29 C ATOM 1386 C LYS A 197 45.283 42.045 -2.450 1.00 32.38 C ATOM 1387 O LYS A 197 45.243 43.102 -1.780 1.00 35.31 O ATOM 1388 CB LYS A 197 43.400 40.448 -1.976 1.00 34.28 C ATOM 1389 CG LYS A 197 42.927 40.753 -3.429 1.00 40.65 C ATOM 1390 CD LYS A 197 41.449 40.286 -3.526 1.00 38.66 C ATOM 1391 CE LYS A 197 40.958 40.732 -4.982 1.00 44.59 C ATOM 1392 NZ LYS A 197 39.677 39.948 -5.199 1.00 45.97 N ATOM 1393 N ASN A 198 45.906 42.061 -3.628 1.00 33.81 N ATOM 1394 CA ASN A 198 46.233 43.270 -4.375 1.00 34.99 C ATOM 1395 C ASN A 198 45.079 43.473 -5.402 1.00 43.29 C ATOM 1396 O ASN A 198 44.677 42.530 -6.079 1.00 36.58 O ATOM 1397 CB ASN A 198 47.541 43.065 -5.168 1.00 29.68 C ATOM 1398 CG ASN A 198 47.852 44.246 -6.056 1.00 40.61 C ATOM 1399 OD1 ASN A 198 48.252 44.193 -7.259 1.00 45.15 O ATOM 1400 ND2 ASN A 198 47.797 45.432 -5.491 1.00 33.27 N ATOM 1401 N PHE A 199 44.488 44.632 -5.442 1.00 46.83 N ATOM 1402 CA PHE A 199 43.310 44.860 -6.278 1.00 44.29 C ATOM 1403 C PHE A 199 43.718 45.401 -7.638 1.00 48.56 C ATOM 1404 O PHE A 199 42.888 45.603 -8.528 1.00 47.88 O ATOM 1405 CB PHE A 199 42.343 45.823 -5.507 1.00 36.43 C ATOM 1406 CG PHE A 199 41.484 45.068 -4.492 1.00 39.46 C ATOM 1407 CD1 PHE A 199 41.995 44.563 -3.327 1.00 34.58 C ATOM 1408 CD2 PHE A 199 40.124 44.847 -4.725 1.00 38.58 C ATOM 1409 CE1 PHE A 199 41.245 43.911 -2.372 1.00 36.89 C ATOM 1410 CE2 PHE A 199 39.357 44.131 -3.832 1.00 39.23 C ATOM 1411 CZ PHE A 199 39.868 43.672 -2.609 1.00 38.56 C ATOM 1412 N ASN A 200 44.985 45.808 -7.791 1.00 45.23 N ATOM 1413 CA ASN A 200 45.535 46.292 -9.034 1.00 48.91 C ATOM 1414 C ASN A 200 44.660 47.372 -9.681 1.00 55.82 C ATOM 1415 O ASN A 200 44.275 47.321 -10.843 1.00 52.33 O ATOM 1416 CB ASN A 200 45.716 45.094 -10.006 1.00 44.73 C ATOM 1417 CG ASN A 200 46.547 45.515 -11.210 1.00 46.80 C ATOM 1418 OD1 ASN A 200 47.424 46.351 -11.099 1.00 47.82 O ATOM 1419 ND2 ASN A 200 46.154 45.100 -12.422 1.00 47.24 N ATOM 1420 N MET A 201 44.400 48.445 -8.941 1.00 51.08 N ATOM 1421 CA MET A 201 43.650 49.588 -9.406 1.00 43.88 C ATOM 1422 C MET A 201 44.538 50.800 -9.464 1.00 48.24 C ATOM 1423 O MET A 201 45.546 50.887 -8.775 1.00 47.14 O ATOM 1424 CB MET A 201 42.431 49.850 -8.483 1.00 36.77 C ATOM 1425 CG MET A 201 41.476 48.634 -8.508 1.00 38.98 C ATOM 1426 SD MET A 201 40.047 49.031 -7.484 1.00 47.67 S ATOM 1427 CE MET A 201 39.500 47.454 -6.999 1.00 37.01 C ATOM 1428 N PRO A 202 44.187 51.773 -10.335 1.00 53.28 N ATOM 1429 CA PRO A 202 44.995 52.964 -10.452 1.00 49.26 C ATOM 1430 C PRO A 202 45.043 53.674 -9.100 1.00 47.98 C ATOM 1431 O PRO A 202 44.030 53.746 -8.397 1.00 42.49 O ATOM 1432 CB PRO A 202 44.249 53.835 -11.482 1.00 57.10 C ATOM 1433 CG PRO A 202 43.156 53.029 -12.026 1.00 53.27 C ATOM 1434 CD PRO A 202 42.998 51.788 -11.189 1.00 51.30 C ATOM 1435 N SER A 203 46.126 54.404 -8.869 1.00 41.99 N ATOM 1436 CA SER A 203 46.244 55.198 -7.666 1.00 48.20 C ATOM 1437 C SER A 203 45.428 56.476 -7.621 1.00 54.70 C ATOM 1438 O SER A 203 45.424 57.165 -6.588 1.00 55.30 O ATOM 1439 CB SER A 203 47.740 55.537 -7.475 1.00 50.74 C ATOM 1440 OG SER A 203 48.387 54.314 -7.106 1.00 57.32 O ATOM 1441 N SER A 204 44.710 56.812 -8.681 1.00 58.99 N ATOM 1442 CA SER A 204 43.930 58.027 -8.839 1.00 59.77 C ATOM 1443 C SER A 204 42.511 57.781 -8.340 1.00 62.32 C ATOM 1444 O SER A 204 41.724 58.733 -8.227 1.00 68.86 O ATOM 1445 CB SER A 204 43.901 58.496 -10.308 1.00 54.42 C ATOM 1446 OG SER A 204 43.296 57.472 -11.119 1.00 57.25 O ATOM 1447 N ASN A 205 42.240 56.523 -7.998 1.00 58.32 N ATOM 1448 CA ASN A 205 40.937 56.266 -7.369 1.00 61.80 C ATOM 1449 C ASN A 205 40.996 55.262 -6.219 1.00 45.16 C ATOM 1450 O ASN A 205 40.358 54.208 -6.247 1.00 45.20 O ATOM 1451 CB ASN A 205 39.906 55.995 -8.446 1.00 67.29 C ATOM 1452 CG ASN A 205 38.485 56.183 -7.998 1.00 71.75 C ATOM 1453 OD1 ASN A 205 37.559 55.653 -8.608 1.00 85.18 O ATOM 1454 ND2 ASN A 205 38.282 56.935 -6.925 1.00 77.85 N ATOM 1455 N ALA A 206 41.383 55.757 -5.042 1.00 47.92 N ATOM 1456 CA ALA A 206 41.224 55.093 -3.718 1.00 39.81 C ATOM 1457 C ALA A 206 39.792 54.848 -3.349 1.00 42.68 C ATOM 1458 O ALA A 206 39.332 53.816 -2.814 1.00 42.93 O ATOM 1459 CB ALA A 206 41.845 56.044 -2.688 1.00 39.81 C ATOM 1460 N GLU A 207 38.931 55.776 -3.839 1.00 47.45 N ATOM 1461 CA GLU A 207 37.489 55.708 -3.564 1.00 48.19 C ATOM 1462 C GLU A 207 36.885 54.458 -4.113 1.00 41.71 C ATOM 1463 O GLU A 207 36.193 53.652 -3.478 1.00 46.31 O ATOM 1464 CB GLU A 207 36.822 56.940 -4.263 1.00 53.24 C ATOM 1465 CG GLU A 207 35.903 57.748 -3.448 1.00 52.06 C ATOM 1466 CD GLU A 207 35.069 58.804 -4.196 1.00 53.54 C ATOM 1467 OE1 GLU A 207 33.836 58.709 -4.042 1.00 52.53 O ATOM 1468 OE2 GLU A 207 35.607 59.696 -4.863 1.00 47.77 O ATOM 1469 N ALA A 208 37.219 54.163 -5.394 1.00 41.35 N ATOM 1470 CA ALA A 208 36.694 52.876 -5.929 1.00 38.60 C ATOM 1471 C ALA A 208 37.329 51.665 -5.286 1.00 30.21 C ATOM 1472 O ALA A 208 36.721 50.582 -5.087 1.00 36.73 O ATOM 1473 CB ALA A 208 36.967 52.922 -7.473 1.00 40.69 C ATOM 1474 N PHE A 209 38.610 51.728 -4.932 1.00 37.86 N ATOM 1475 CA PHE A 209 39.264 50.540 -4.250 1.00 35.24 C ATOM 1476 C PHE A 209 38.659 50.292 -2.898 1.00 27.70 C ATOM 1477 O PHE A 209 38.178 49.180 -2.484 1.00 33.02 O ATOM 1478 CB PHE A 209 40.751 50.972 -4.087 1.00 40.16 C ATOM 1479 CG PHE A 209 41.518 50.251 -2.997 1.00 37.15 C ATOM 1480 CD1 PHE A 209 42.048 50.936 -1.925 1.00 43.01 C ATOM 1481 CD2 PHE A 209 41.758 48.899 -3.108 1.00 35.23 C ATOM 1482 CE1 PHE A 209 42.759 50.304 -0.878 1.00 39.83 C ATOM 1483 CE2 PHE A 209 42.496 48.240 -2.108 1.00 41.17 C ATOM 1484 CZ PHE A 209 43.014 48.926 -1.023 1.00 36.13 C ATOM 1485 N ASN A 210 38.435 51.432 -2.181 1.00 34.06 N ATOM 1486 CA ASN A 210 37.758 51.323 -0.856 1.00 33.13 C ATOM 1487 C ASN A 210 36.459 50.642 -0.921 1.00 36.45 C ATOM 1488 O ASN A 210 36.043 49.760 -0.126 1.00 38.89 O ATOM 1489 CB ASN A 210 37.604 52.753 -0.238 1.00 38.25 C ATOM 1490 CG ASN A 210 38.897 53.225 0.366 1.00 40.22 C ATOM 1491 OD1 ASN A 210 39.791 52.376 0.710 1.00 39.40 O ATOM 1492 ND2 ASN A 210 39.122 54.514 0.571 1.00 35.92 N ATOM 1493 N ALA A 211 35.651 51.028 -1.963 1.00 38.18 N ATOM 1494 CA ALA A 211 34.315 50.403 -2.077 1.00 30.49 C ATOM 1495 C ALA A 211 34.389 48.972 -2.530 1.00 29.98 C ATOM 1496 O ALA A 211 33.619 48.095 -2.092 1.00 37.61 O ATOM 1497 CB ALA A 211 33.603 51.170 -3.294 1.00 39.39 C ATOM 1498 N LYS A 212 35.310 48.650 -3.477 1.00 39.69 N ATOM 1499 CA LYS A 212 35.439 47.198 -3.836 1.00 38.37 C ATOM 1500 C LYS A 212 35.940 46.321 -2.712 1.00 34.93 C ATOM 1501 O LYS A 212 35.424 45.202 -2.485 1.00 39.08 O ATOM 1502 CB LYS A 212 36.393 47.094 -5.057 1.00 46.63 C ATOM 1503 CG LYS A 212 36.682 45.722 -5.599 1.00 57.16 C ATOM 1504 CD LYS A 212 35.467 44.844 -5.911 1.00 66.83 C ATOM 1505 CE LYS A 212 35.834 43.798 -6.972 1.00 75.31 C ATOM 1506 NZ LYS A 212 35.215 42.455 -6.751 1.00 83.83 N ATOM 1507 N VAL A 213 36.742 46.853 -1.775 1.00 39.52 N ATOM 1508 CA VAL A 213 37.137 45.993 -0.595 1.00 34.95 C ATOM 1509 C VAL A 213 35.937 45.706 0.241 1.00 34.32 C ATOM 1510 O VAL A 213 35.621 44.556 0.620 1.00 36.43 O ATOM 1511 CB VAL A 213 38.235 46.736 0.233 1.00 34.88 C ATOM 1512 CG1 VAL A 213 38.526 45.954 1.522 1.00 41.19 C ATOM 1513 CG2 VAL A 213 39.501 46.842 -0.613 1.00 39.21 C ATOM 1514 N LEU A 214 35.078 46.743 0.392 1.00 34.56 N ATOM 1515 CA LEU A 214 33.852 46.584 1.227 1.00 36.30 C ATOM 1516 C LEU A 214 32.826 45.681 0.601 1.00 32.58 C ATOM 1517 O LEU A 214 32.215 44.794 1.229 1.00 37.74 O ATOM 1518 CB LEU A 214 33.186 47.970 1.528 1.00 35.38 C ATOM 1519 CG LEU A 214 34.085 48.864 2.445 1.00 42.18 C ATOM 1520 CD1 LEU A 214 33.596 50.312 2.444 1.00 40.58 C ATOM 1521 CD2 LEU A 214 34.102 48.285 3.861 1.00 35.31 C ATOM 1522 N GLU A 215 32.716 45.795 -0.740 1.00 33.38 N ATOM 1523 CA GLU A 215 31.918 44.811 -1.467 1.00 35.66 C ATOM 1524 C GLU A 215 32.451 43.406 -1.286 1.00 39.58 C ATOM 1525 O GLU A 215 31.721 42.429 -1.031 1.00 37.13 O ATOM 1526 CB GLU A 215 32.020 45.218 -2.983 1.00 36.92 C ATOM 1527 CG GLU A 215 31.157 44.299 -3.847 1.00 46.72 C ATOM 1528 CD GLU A 215 31.241 44.669 -5.330 1.00 52.36 C ATOM 1529 OE1 GLU A 215 30.732 43.865 -6.131 1.00 65.70 O ATOM 1530 OE2 GLU A 215 31.781 45.704 -5.751 1.00 57.02 O ATOM 1531 N GLU A 216 33.798 43.236 -1.326 1.00 35.91 N ATOM 1532 CA GLU A 216 34.169 41.759 -1.169 1.00 37.99 C ATOM 1533 C GLU A 216 33.944 41.280 0.229 1.00 31.80 C ATOM 1534 O GLU A 216 33.561 40.137 0.489 1.00 38.25 O ATOM 1535 CB GLU A 216 35.631 41.575 -1.629 1.00 38.38 C ATOM 1536 CG GLU A 216 35.662 41.797 -3.159 1.00 50.95 C ATOM 1537 CD GLU A 216 37.021 41.434 -3.756 1.00 55.17 C ATOM 1538 OE1 GLU A 216 37.834 40.743 -3.083 1.00 54.63 O ATOM 1539 OE2 GLU A 216 37.192 41.894 -4.900 1.00 59.50 O ATOM 1540 N LEU A 217 34.254 42.157 1.205 1.00 34.08 N ATOM 1541 CA LEU A 217 34.036 41.841 2.600 1.00 37.75 C ATOM 1542 C LEU A 217 32.577 41.475 2.854 1.00 37.81 C ATOM 1543 O LEU A 217 32.321 40.510 3.597 1.00 40.00 O ATOM 1544 CB LEU A 217 34.431 43.102 3.483 1.00 36.20 C ATOM 1545 CG LEU A 217 35.960 43.308 3.570 1.00 40.90 C ATOM 1546 CD1 LEU A 217 36.317 44.584 4.346 1.00 39.26 C ATOM 1547 CD2 LEU A 217 36.619 42.079 4.203 1.00 38.73 C ATOM 1548 N ARG A 218 31.615 42.259 2.370 1.00 41.66 N ATOM 1549 CA ARG A 218 30.180 41.898 2.574 1.00 40.32 C ATOM 1550 C ARG A 218 29.833 40.540 2.043 1.00 40.34 C ATOM 1551 O ARG A 218 29.311 39.668 2.790 1.00 42.81 O ATOM 1552 CB ARG A 218 29.267 42.933 1.880 1.00 47.48 C ATOM 1553 CG ARG A 218 29.209 44.280 2.588 1.00 46.80 C ATOM 1554 CD ARG A 218 27.848 44.986 2.288 1.00 46.54 C ATOM 1555 NE ARG A 218 27.827 45.302 0.872 1.00 42.44 N ATOM 1556 CZ ARG A 218 28.521 46.231 0.293 1.00 46.33 C ATOM 1557 NH1 ARG A 218 29.185 47.121 1.019 1.00 54.67 N ATOM 1558 NH2 ARG A 218 28.547 46.269 -1.034 1.00 49.32 N ATOM 1559 N GLU A 219 30.439 40.158 0.879 1.00 42.30 N ATOM 1560 CA GLU A 219 30.197 38.775 0.427 1.00 40.93 C ATOM 1561 C GLU A 219 30.888 37.718 1.254 1.00 44.45 C ATOM 1562 O GLU A 219 30.337 36.644 1.583 1.00 43.13 O ATOM 1563 CB GLU A 219 30.589 38.713 -1.068 1.00 47.96 C ATOM 1564 CG GLU A 219 30.197 37.376 -1.689 1.00 61.31 C ATOM 1565 CD GLU A 219 28.725 37.182 -1.963 1.00 72.92 C ATOM 1566 OE1 GLU A 219 27.875 38.089 -1.826 1.00 72.60 O ATOM 1567 OE2 GLU A 219 28.416 36.018 -2.356 1.00 80.44 O ATOM 1568 N LYS A 220 32.113 37.973 1.750 1.00 42.34 N ATOM 1569 CA LYS A 220 32.834 36.904 2.489 1.00 40.56 C ATOM 1570 C LYS A 220 32.254 36.666 3.858 1.00 39.28 C ATOM 1571 O LYS A 220 32.437 35.577 4.420 1.00 39.99 O ATOM 1572 CB LYS A 220 34.329 37.320 2.612 1.00 44.71 C ATOM 1573 CG LYS A 220 35.115 37.352 1.317 1.00 42.76 C ATOM 1574 CD LYS A 220 36.637 37.421 1.523 1.00 45.37 C ATOM 1575 CE LYS A 220 37.209 38.620 2.197 1.00 42.98 C ATOM 1576 NZ LYS A 220 38.649 38.933 1.799 1.00 39.00 N ATOM 1577 N VAL A 221 31.611 37.639 4.532 1.00 35.24 N ATOM 1578 CA VAL A 221 31.040 37.343 5.860 1.00 43.74 C ATOM 1579 C VAL A 221 29.724 36.596 5.820 1.00 47.02 C ATOM 1580 O VAL A 221 29.285 36.038 6.851 1.00 42.05 O ATOM 1581 CB VAL A 221 30.835 38.600 6.745 1.00 48.81 C ATOM 1582 CG1 VAL A 221 32.163 39.321 6.964 1.00 42.03 C ATOM 1583 CG2 VAL A 221 29.836 39.577 6.135 1.00 45.03 C ATOM 1584 N LYS A 222 29.080 36.521 4.635 1.00 48.65 N ATOM 1585 CA LYS A 222 27.789 35.858 4.546 1.00 48.91 C ATOM 1586 C LYS A 222 27.882 34.427 5.015 1.00 50.41 C ATOM 1587 O LYS A 222 28.771 33.723 4.548 1.00 48.81 O ATOM 1588 CB LYS A 222 27.242 35.857 3.094 1.00 52.63 C ATOM 1589 CG LYS A 222 26.614 37.206 2.734 1.00 63.01 C ATOM 1590 CD LYS A 222 25.983 37.124 1.346 1.00 72.43 C ATOM 1591 CE LYS A 222 25.835 38.523 0.729 1.00 75.51 C ATOM 1592 NZ LYS A 222 25.664 38.392 -0.762 1.00 77.73 N ATOM 1593 N GLY A 223 26.930 33.991 5.861 1.00 49.46 N ATOM 1594 CA GLY A 223 26.908 32.618 6.322 1.00 46.47 C ATOM 1595 C GLY A 223 27.730 32.397 7.583 1.00 50.92 C ATOM 1596 O GLY A 223 27.580 31.371 8.272 1.00 49.86 O ATOM 1597 N LEU A 224 28.717 33.287 7.827 1.00 46.85 N ATOM 1598 CA LEU A 224 29.611 33.009 8.951 1.00 43.29 C ATOM 1599 C LEU A 224 29.029 33.351 10.298 1.00 44.80 C ATOM 1600 O LEU A 224 28.217 34.281 10.504 1.00 45.46 O ATOM 1601 CB LEU A 224 30.946 33.752 8.721 1.00 43.06 C ATOM 1602 CG LEU A 224 31.690 33.282 7.453 1.00 48.49 C ATOM 1603 CD1 LEU A 224 33.004 34.034 7.310 1.00 50.91 C ATOM 1604 CD2 LEU A 224 31.877 31.763 7.347 1.00 35.44 C ATOM 1605 N TYR A 225 29.505 32.608 11.306 1.00 41.70 N ATOM 1606 CA TYR A 225 29.157 32.984 12.681 1.00 37.90 C ATOM 1607 C TYR A 225 30.191 34.020 13.166 1.00 40.91 C ATOM 1608 O TYR A 225 31.261 33.652 13.719 1.00 39.37 O ATOM 1609 CB TYR A 225 29.181 31.754 13.576 1.00 33.82 C ATOM 1610 CG TYR A 225 28.580 32.041 14.926 1.00 36.77 C ATOM 1611 CD1 TYR A 225 29.292 31.862 16.098 1.00 41.08 C ATOM 1612 CD2 TYR A 225 27.236 32.450 15.006 1.00 41.99 C ATOM 1613 CE1 TYR A 225 28.725 32.102 17.345 1.00 40.24 C ATOM 1614 CE2 TYR A 225 26.629 32.722 16.253 1.00 40.44 C ATOM 1615 CZ TYR A 225 27.379 32.529 17.393 1.00 45.90 C ATOM 1616 OH TYR A 225 26.825 32.782 18.623 1.00 46.91 O ATOM 1617 N LEU A 226 29.836 35.286 13.135 1.00 37.06 N ATOM 1618 CA LEU A 226 30.661 36.422 13.457 1.00 42.47 C ATOM 1619 C LEU A 226 31.300 36.431 14.829 1.00 42.81 C ATOM 1620 O LEU A 226 32.513 36.767 14.933 1.00 36.33 O ATOM 1621 CB LEU A 226 30.059 37.779 13.058 1.00 37.32 C ATOM 1622 CG LEU A 226 29.698 37.967 11.574 1.00 46.71 C ATOM 1623 CD1 LEU A 226 29.292 39.410 11.263 1.00 45.62 C ATOM 1624 CD2 LEU A 226 30.846 37.602 10.612 1.00 38.41 C ATOM 1625 N PRO A 227 30.677 35.908 15.876 1.00 40.27 N ATOM 1626 CA PRO A 227 31.332 35.821 17.192 1.00 39.13 C ATOM 1627 C PRO A 227 32.503 34.845 17.110 1.00 39.19 C ATOM 1628 O PRO A 227 33.482 34.931 17.868 1.00 38.11 O ATOM 1629 CB PRO A 227 30.227 35.353 18.159 1.00 39.54 C ATOM 1630 CG PRO A 227 28.954 35.948 17.474 1.00 41.26 C ATOM 1631 CD PRO A 227 29.197 35.699 15.993 1.00 41.40 C ATOM 1632 N SER A 228 32.488 33.871 16.188 1.00 38.91 N ATOM 1633 CA SER A 228 33.623 32.971 16.013 1.00 38.41 C ATOM 1634 C SER A 228 34.856 33.763 15.533 1.00 37.27 C ATOM 1635 O SER A 228 35.973 33.513 16.031 1.00 35.81 O ATOM 1636 CB SER A 228 33.291 31.890 14.979 1.00 38.72 C ATOM 1637 OG SER A 228 32.491 30.828 15.510 1.00 39.18 O ATOM 1638 N CYS A 229 34.696 34.776 14.692 1.00 34.92 N ATOM 1639 CA CYS A 229 35.828 35.628 14.285 1.00 33.82 C ATOM 1640 C CYS A 229 36.511 36.285 15.469 1.00 35.87 C ATOM 1641 O CYS A 229 37.749 36.324 15.624 1.00 35.14 O ATOM 1642 CB CYS A 229 35.328 36.756 13.361 1.00 33.38 C ATOM 1643 SG CYS A 229 34.563 36.084 11.844 1.00 32.27 S ATOM 1644 N LEU A 230 35.713 36.822 16.401 1.00 34.47 N ATOM 1645 CA LEU A 230 36.266 37.497 17.578 1.00 33.19 C ATOM 1646 C LEU A 230 36.909 36.514 18.532 1.00 34.65 C ATOM 1647 O LEU A 230 37.912 36.885 19.162 1.00 34.43 O ATOM 1648 CB LEU A 230 35.136 38.286 18.314 1.00 33.11 C ATOM 1649 CG LEU A 230 34.489 39.341 17.371 1.00 39.64 C ATOM 1650 CD1 LEU A 230 33.673 40.366 18.191 1.00 39.52 C ATOM 1651 CD2 LEU A 230 35.552 40.067 16.540 1.00 31.77 C ATOM 1652 N GLY A 231 36.316 35.330 18.665 1.00 32.60 N ATOM 1653 CA GLY A 231 36.861 34.325 19.618 1.00 34.04 C ATOM 1654 C GLY A 231 38.223 33.814 19.087 1.00 38.55 C ATOM 1655 O GLY A 231 39.150 33.529 19.829 1.00 30.79 O ATOM 1656 N MET A 232 38.375 33.606 17.773 1.00 31.70 N ATOM 1657 CA MET A 232 39.628 33.150 17.193 1.00 31.72 C ATOM 1658 C MET A 232 40.683 34.261 17.305 1.00 30.72 C ATOM 1659 O MET A 232 41.802 33.999 17.736 1.00 30.28 O ATOM 1660 CB MET A 232 39.421 32.753 15.723 1.00 31.79 C ATOM 1661 CG MET A 232 38.689 31.416 15.560 1.00 33.71 C ATOM 1662 SD MET A 232 38.694 30.868 13.842 1.00 31.14 S ATOM 1663 CE MET A 232 37.488 32.044 13.168 1.00 28.05 C ATOM 1664 N LYS A 233 40.274 35.515 17.124 1.00 30.51 N ATOM 1665 CA LYS A 233 41.174 36.655 17.242 1.00 32.28 C ATOM 1666 C LYS A 233 41.680 36.773 18.683 1.00 33.66 C ATOM 1667 O LYS A 233 42.906 36.872 18.913 1.00 33.17 O ATOM 1668 CB LYS A 233 40.593 38.016 16.822 1.00 30.21 C ATOM 1669 CG LYS A 233 41.505 39.167 17.253 1.00 31.25 C ATOM 1670 CD LYS A 233 41.284 40.525 16.614 1.00 31.83 C ATOM 1671 CE LYS A 233 42.365 41.493 17.076 1.00 29.50 C ATOM 1672 NZ LYS A 233 42.420 42.808 16.390 1.00 27.29 N ATOM 1673 N LYS A 234 40.758 36.617 19.622 1.00 27.46 N ATOM 1674 CA LYS A 234 41.215 36.669 21.040 1.00 30.96 C ATOM 1675 C LYS A 234 42.316 35.630 21.327 1.00 31.36 C ATOM 1676 O LYS A 234 43.325 35.877 21.970 1.00 31.53 O ATOM 1677 CB LYS A 234 40.003 36.388 21.922 1.00 30.69 C ATOM 1678 CG LYS A 234 40.297 36.482 23.431 1.00 38.05 C ATOM 1679 CD LYS A 234 39.003 36.004 24.131 1.00 45.46 C ATOM 1680 CE LYS A 234 39.091 36.401 25.635 1.00 53.21 C ATOM 1681 NZ LYS A 234 38.011 35.618 26.360 1.00 55.81 N ATOM 1682 N LEU A 235 42.132 34.389 20.868 1.00 29.11 N ATOM 1683 CA LEU A 235 43.158 33.369 21.078 1.00 30.12 C ATOM 1684 C LEU A 235 44.405 33.670 20.245 1.00 34.54 C ATOM 1685 O LEU A 235 45.532 33.630 20.764 1.00 30.95 O ATOM 1686 CB LEU A 235 42.572 31.989 20.715 1.00 36.98 C ATOM 1687 CG LEU A 235 41.347 31.567 21.530 1.00 43.90 C ATOM 1688 CD1 LEU A 235 40.973 30.103 21.324 1.00 41.69 C ATOM 1689 CD2 LEU A 235 41.492 31.841 23.016 1.00 46.10 C ATOM 1690 N LEU A 236 44.205 34.157 19.008 1.00 34.07 N ATOM 1691 CA LEU A 236 45.342 34.455 18.122 1.00 32.05 C ATOM 1692 C LEU A 236 46.227 35.509 18.712 1.00 30.99 C ATOM 1693 O LEU A 236 47.457 35.370 18.692 1.00 30.71 O ATOM 1694 CB LEU A 236 44.924 34.838 16.740 1.00 32.72 C ATOM 1695 CG LEU A 236 44.858 33.938 15.539 1.00 43.13 C ATOM 1696 CD1 LEU A 236 45.424 32.543 15.621 1.00 35.94 C ATOM 1697 CD2 LEU A 236 43.541 34.055 14.802 1.00 34.89 C ATOM 1698 N LYS A 237 45.619 36.600 19.214 1.00 31.84 N ATOM 1699 CA LYS A 237 46.316 37.710 19.797 1.00 32.30 C ATOM 1700 C LYS A 237 47.086 37.335 21.076 1.00 37.24 C ATOM 1701 O LYS A 237 48.149 37.943 21.384 1.00 29.60 O ATOM 1702 CB LYS A 237 45.298 38.857 20.187 1.00 36.85 C ATOM 1703 CG LYS A 237 44.946 39.731 18.941 1.00 48.40 C ATOM 1704 CD LYS A 237 45.590 41.102 18.881 1.00 48.79 C ATOM 1705 CE LYS A 237 44.740 42.265 19.524 1.00 42.53 C ATOM 1706 NZ LYS A 237 43.949 41.844 20.743 1.00 45.66 N ATOM 1707 N SER A 238 46.707 36.260 21.774 1.00 34.79 N ATOM 1708 CA SER A 238 47.444 35.939 23.027 1.00 37.22 C ATOM 1709 C SER A 238 48.820 35.375 22.720 1.00 35.62 C ATOM 1710 O SER A 238 49.689 35.317 23.585 1.00 39.57 O ATOM 1711 CB SER A 238 46.611 34.950 23.879 1.00 35.05 C ATOM 1712 OG SER A 238 46.650 33.690 23.204 1.00 43.02 O ATOM 1713 N ASN A 239 49.112 34.995 21.462 1.00 33.17 N ATOM 1714 CA ASN A 239 50.456 34.538 21.115 1.00 37.18 C ATOM 1715 C ASN A 239 51.470 35.694 21.389 1.00 37.60 C ATOM 1716 O ASN A 239 52.575 35.433 21.774 1.00 34.70 O ATOM 1717 CB ASN A 239 50.556 34.275 19.587 1.00 33.28 C ATOM 1718 CG ASN A 239 49.951 32.947 19.134 1.00 40.90 C ATOM 1719 OD1 ASN A 239 50.061 31.938 19.813 1.00 49.19 O ATOM 1720 ND2 ASN A 239 49.228 32.854 18.018 1.00 31.74 N ATOM 1721 N HIS A 240 51.237 36.937 20.951 1.00 35.79 N ATOM 1722 CA HIS A 240 52.298 37.976 21.007 1.00 31.77 C ATOM 1723 C HIS A 240 51.865 39.195 21.794 1.00 38.51 C ATOM 1724 O HIS A 240 52.611 40.183 21.832 1.00 32.23 O ATOM 1725 CB HIS A 240 52.612 38.441 19.551 1.00 34.11 C ATOM 1726 CG HIS A 240 53.139 37.282 18.738 1.00 35.64 C ATOM 1727 ND1 HIS A 240 54.258 36.598 19.152 1.00 39.40 N ATOM 1728 CD2 HIS A 240 52.689 36.661 17.609 1.00 29.90 C ATOM 1729 CE1 HIS A 240 54.540 35.630 18.312 1.00 35.74 C ATOM 1730 NE2 HIS A 240 53.597 35.625 17.388 1.00 33.84 N ATOM 1731 N ILE A 241 50.694 39.152 22.477 1.00 38.31 N ATOM 1732 CA ILE A 241 50.186 40.346 23.122 1.00 39.09 C ATOM 1733 C ILE A 241 51.093 40.874 24.212 1.00 37.09 C ATOM 1734 O ILE A 241 51.284 42.111 24.252 1.00 36.94 O ATOM 1735 CB ILE A 241 48.732 40.323 23.639 1.00 40.56 C ATOM 1736 CG1 ILE A 241 48.405 41.788 24.157 1.00 45.19 C ATOM 1737 CG2 ILE A 241 48.576 39.367 24.803 1.00 34.81 C ATOM 1738 CD1 ILE A 241 47.155 42.350 23.544 1.00 50.06 C ATOM 1739 N ASP A 242 51.673 40.075 25.080 1.00 34.78 N ATOM 1740 CA ASP A 242 52.621 40.553 26.052 1.00 38.44 C ATOM 1741 C ASP A 242 53.862 41.179 25.402 1.00 35.92 C ATOM 1742 O ASP A 242 54.422 42.161 25.895 1.00 32.80 O ATOM 1743 CB ASP A 242 53.119 39.416 26.967 1.00 41.64 C ATOM 1744 CG ASP A 242 51.971 38.875 27.822 1.00 50.76 C ATOM 1745 OD1 ASP A 242 50.897 39.517 27.894 1.00 47.45 O ATOM 1746 OD2 ASP A 242 52.214 37.811 28.432 1.00 53.16 O ATOM 1747 N ALA A 243 54.363 40.503 24.353 1.00 31.84 N ATOM 1748 CA ALA A 243 55.528 41.086 23.659 1.00 30.56 C ATOM 1749 C ALA A 243 55.137 42.462 23.113 1.00 31.03 C ATOM 1750 O ALA A 243 55.940 43.381 23.172 1.00 28.48 O ATOM 1751 CB ALA A 243 55.989 40.144 22.541 1.00 30.99 C ATOM 1752 N PHE A 244 53.936 42.606 22.512 1.00 30.79 N ATOM 1753 CA PHE A 244 53.563 43.898 21.940 1.00 32.41 C ATOM 1754 C PHE A 244 53.465 44.950 23.046 1.00 29.61 C ATOM 1755 O PHE A 244 53.982 46.051 22.874 1.00 29.31 O ATOM 1756 CB PHE A 244 52.228 43.822 21.141 1.00 28.60 C ATOM 1757 CG PHE A 244 52.454 43.422 19.695 1.00 28.63 C ATOM 1758 CD1 PHE A 244 52.118 42.161 19.236 1.00 33.37 C ATOM 1759 CD2 PHE A 244 53.165 44.278 18.851 1.00 28.23 C ATOM 1760 CE1 PHE A 244 52.325 41.794 17.906 1.00 35.18 C ATOM 1761 CE2 PHE A 244 53.275 43.952 17.518 1.00 32.29 C ATOM 1762 CZ PHE A 244 52.957 42.686 17.067 1.00 33.81 C ATOM 1763 N ASN A 245 52.814 44.636 24.173 1.00 29.50 N ATOM 1764 CA ASN A 245 52.691 45.639 25.262 1.00 32.27 C ATOM 1765 C ASN A 245 54.065 46.010 25.809 1.00 33.53 C ATOM 1766 O ASN A 245 54.354 47.143 26.109 1.00 35.65 O ATOM 1767 CB ASN A 245 51.812 45.074 26.384 1.00 29.63 C ATOM 1768 CG ASN A 245 50.336 45.188 25.944 1.00 33.09 C ATOM 1769 OD1 ASN A 245 50.029 46.110 25.219 1.00 35.78 O ATOM 1770 ND2 ASN A 245 49.522 44.305 26.442 1.00 29.33 N ATOM 1771 N LYS A 246 54.922 44.986 25.958 1.00 32.88 N ATOM 1772 CA LYS A 246 56.277 45.265 26.409 1.00 35.55 C ATOM 1773 C LYS A 246 56.984 46.172 25.430 1.00 37.17 C ATOM 1774 O LYS A 246 57.597 47.149 25.859 1.00 31.24 O ATOM 1775 CB LYS A 246 57.050 43.954 26.652 1.00 34.11 C ATOM 1776 CG LYS A 246 58.516 44.251 27.025 1.00 46.12 C ATOM 1777 CD LYS A 246 59.196 42.910 27.382 1.00 50.76 C ATOM 1778 CE LYS A 246 60.580 43.179 27.996 1.00 57.53 C ATOM 1779 NZ LYS A 246 61.433 41.950 27.898 1.00 57.88 N ATOM 1780 N ALA A 247 56.988 45.839 24.116 1.00 33.86 N ATOM 1781 CA ALA A 247 57.638 46.706 23.133 1.00 30.73 C ATOM 1782 C ALA A 247 57.140 48.153 23.164 1.00 32.02 C ATOM 1783 O ALA A 247 57.912 49.120 23.109 1.00 31.35 O ATOM 1784 CB ALA A 247 57.362 46.133 21.719 1.00 30.37 C ATOM 1785 N ASN A 248 55.829 48.356 23.304 1.00 29.69 N ATOM 1786 CA ASN A 248 55.281 49.703 23.380 1.00 37.16 C ATOM 1787 C ASN A 248 55.949 50.462 24.545 1.00 40.34 C ATOM 1788 O ASN A 248 56.440 51.618 24.392 1.00 36.99 O ATOM 1789 CB ASN A 248 53.745 49.673 23.596 1.00 32.98 C ATOM 1790 CG ASN A 248 53.087 51.014 23.195 1.00 34.11 C ATOM 1791 OD1 ASN A 248 53.670 51.864 22.533 1.00 38.25 O ATOM 1792 ND2 ASN A 248 51.837 51.179 23.560 1.00 36.97 N ATOM 1793 N SER A 249 56.073 49.781 25.684 1.00 34.93 N ATOM 1794 CA SER A 249 56.709 50.478 26.846 1.00 35.27 C ATOM 1795 C SER A 249 58.203 50.636 26.737 1.00 38.20 C ATOM 1796 O SER A 249 58.762 51.756 26.931 1.00 34.49 O ATOM 1797 CB SER A 249 56.343 49.702 28.152 1.00 33.01 C ATOM 1798 OG SER A 249 57.307 50.254 29.111 1.00 41.16 O ATOM 1799 N VAL A 250 58.975 49.617 26.268 1.00 33.43 N ATOM 1800 CA VAL A 250 60.414 49.848 26.159 1.00 36.33 C ATOM 1801 C VAL A 250 60.782 50.712 24.963 1.00 40.97 C ATOM 1802 O VAL A 250 61.898 51.322 24.938 1.00 33.61 O ATOM 1803 CB VAL A 250 61.280 48.559 26.143 1.00 42.22 C ATOM 1804 CG1 VAL A 250 60.793 47.558 27.232 1.00 35.05 C ATOM 1805 CG2 VAL A 250 61.292 47.891 24.796 1.00 43.52 C ATOM 1806 N GLU A 251 59.952 50.710 23.876 1.00 31.36 N ATOM 1807 CA GLU A 251 60.360 51.665 22.787 1.00 31.48 C ATOM 1808 C GLU A 251 60.392 53.094 23.369 1.00 35.51 C ATOM 1809 O GLU A 251 61.242 53.911 23.036 1.00 33.24 O ATOM 1810 CB GLU A 251 59.361 51.623 21.633 1.00 30.33 C ATOM 1811 CG GLU A 251 59.605 50.328 20.800 1.00 31.29 C ATOM 1812 CD GLU A 251 58.460 50.019 19.861 1.00 31.37 C ATOM 1813 OE1 GLU A 251 57.401 50.659 19.952 1.00 30.31 O ATOM 1814 OE2 GLU A 251 58.591 49.039 19.095 1.00 34.99 O ATOM 1815 N VAL A 252 59.376 53.428 24.134 1.00 33.14 N ATOM 1816 CA VAL A 252 59.244 54.772 24.721 1.00 46.46 C ATOM 1817 C VAL A 252 60.323 55.045 25.752 1.00 49.14 C ATOM 1818 O VAL A 252 61.173 55.937 25.568 1.00 46.11 O ATOM 1819 CB VAL A 252 57.817 54.851 25.330 1.00 50.98 C ATOM 1820 CG1 VAL A 252 57.642 56.092 26.184 1.00 65.78 C ATOM 1821 CG2 VAL A 252 56.872 54.841 24.144 1.00 56.87 C ATOM 1822 N ASN A 253 60.579 54.062 26.648 1.00 46.11 N ATOM 1823 CA ASN A 253 61.651 54.223 27.620 1.00 44.65 C ATOM 1824 C ASN A 253 62.984 54.484 26.945 1.00 50.60 C ATOM 1825 O ASN A 253 63.774 55.377 27.308 1.00 51.43 O ATOM 1826 CB ASN A 253 61.843 53.028 28.556 1.00 45.83 C ATOM 1827 CG ASN A 253 60.669 52.817 29.484 1.00 50.07 C ATOM 1828 OD1 ASN A 253 59.798 53.666 29.593 1.00 44.41 O ATOM 1829 ND2 ASN A 253 60.662 51.641 30.129 1.00 56.78 N ATOM 1830 N GLU A 254 63.251 53.669 25.910 1.00 47.02 N ATOM 1831 CA GLU A 254 64.542 53.766 25.252 1.00 40.01 C ATOM 1832 C GLU A 254 64.735 55.053 24.458 1.00 39.11 C ATOM 1833 O GLU A 254 65.871 55.450 24.245 1.00 37.73 O ATOM 1834 CB GLU A 254 64.750 52.555 24.345 1.00 52.85 C ATOM 1835 CG GLU A 254 66.137 52.025 24.408 1.00 61.68 C ATOM 1836 CD GLU A 254 66.576 51.281 25.646 1.00 60.45 C ATOM 1837 OE1 GLU A 254 65.725 50.690 26.322 1.00 74.13 O ATOM 1838 OE2 GLU A 254 67.739 51.111 26.056 1.00 68.64 O ATOM 1839 N SER A 255 63.702 55.620 23.833 1.00 38.46 N ATOM 1840 CA SER A 255 63.879 56.806 23.034 1.00 41.31 C ATOM 1841 C SER A 255 64.265 58.059 23.879 1.00 46.87 C ATOM 1842 O SER A 255 64.749 59.025 23.284 1.00 43.58 O ATOM 1843 CB SER A 255 62.515 57.142 22.364 1.00 40.60 C ATOM 1844 OG SER A 255 61.617 57.462 23.418 1.00 43.95 O ATOM 1845 N LEU A 256 63.880 58.123 25.157 1.00 42.70 N ATOM 1846 CA LEU A 256 64.001 59.328 25.979 1.00 49.70 C ATOM 1847 C LEU A 256 65.387 59.945 25.914 1.00 48.22 C ATOM 1848 O LEU A 256 65.533 61.136 25.625 1.00 47.70 O ATOM 1849 CB LEU A 256 63.591 59.050 27.440 1.00 44.57 C ATOM 1850 CG LEU A 256 62.078 58.723 27.612 1.00 44.03 C ATOM 1851 CD1 LEU A 256 61.775 58.668 29.096 1.00 56.71 C ATOM 1852 CD2 LEU A 256 61.148 59.634 26.879 1.00 45.93 C ATOM 1853 N LYS A 257 66.444 59.114 25.972 1.00 46.27 N ATOM 1854 CA LYS A 257 67.787 59.660 25.828 1.00 46.98 C ATOM 1855 C LYS A 257 68.060 60.213 24.444 1.00 49.53 C ATOM 1856 O LYS A 257 69.045 60.979 24.282 1.00 48.58 O ATOM 1857 CB LYS A 257 68.871 58.654 26.195 1.00 50.82 C ATOM 1858 CG LYS A 257 68.980 57.471 25.236 1.00 58.55 C ATOM 1859 CD LYS A 257 70.363 56.829 25.467 1.00 59.29 C ATOM 1860 CE LYS A 257 70.323 55.380 25.000 1.00 59.86 C ATOM 1861 NZ LYS A 257 69.472 54.617 25.978 1.00 66.92 N ATOM 1862 N TYR A 258 67.413 59.655 23.406 1.00 42.45 N ATOM 1863 CA TYR A 258 67.597 60.223 22.059 1.00 43.67 C ATOM 1864 C TYR A 258 67.039 61.649 22.094 1.00 49.95 C ATOM 1865 O TYR A 258 67.711 62.556 21.622 1.00 53.25 O ATOM 1866 CB TYR A 258 66.920 59.363 20.959 1.00 43.08 C ATOM 1867 CG TYR A 258 67.672 58.039 20.760 1.00 35.80 C ATOM 1868 CD1 TYR A 258 67.492 56.992 21.693 1.00 38.06 C ATOM 1869 CD2 TYR A 258 68.561 57.880 19.748 1.00 37.19 C ATOM 1870 CE1 TYR A 258 68.203 55.801 21.559 1.00 37.37 C ATOM 1871 CE2 TYR A 258 69.295 56.695 19.579 1.00 37.70 C ATOM 1872 CZ TYR A 258 69.113 55.681 20.509 1.00 39.03 C ATOM 1873 OH TYR A 258 69.809 54.525 20.361 1.00 39.75 O ATOM 1874 N TRP A 259 65.863 61.838 22.704 1.00 49.15 N ATOM 1875 CA TRP A 259 65.291 63.164 22.846 1.00 58.62 C ATOM 1876 C TRP A 259 66.155 64.061 23.751 1.00 64.63 C ATOM 1877 O TRP A 259 66.434 65.209 23.412 1.00 61.49 O ATOM 1878 CB TRP A 259 63.860 63.110 23.370 1.00 53.57 C ATOM 1879 CG TRP A 259 62.852 62.517 22.439 1.00 56.65 C ATOM 1880 CD1 TRP A 259 62.263 61.276 22.545 1.00 53.73 C ATOM 1881 CD2 TRP A 259 62.263 63.139 21.281 1.00 55.73 C ATOM 1882 NE1 TRP A 259 61.341 61.109 21.542 1.00 54.67 N ATOM 1883 CE2 TRP A 259 61.341 62.219 20.733 1.00 54.74 C ATOM 1884 CE3 TRP A 259 62.402 64.392 20.679 1.00 54.07 C ATOM 1885 CZ2 TRP A 259 60.582 62.507 19.605 1.00 53.44 C ATOM 1886 CZ3 TRP A 259 61.645 64.692 19.557 1.00 58.75 C ATOM 1887 CH2 TRP A 259 60.731 63.752 19.035 1.00 59.53 C ATOM 1888 N VAL A 260 66.664 63.533 24.868 1.00 66.44 N ATOM 1889 CA VAL A 260 67.502 64.364 25.748 1.00 66.55 C ATOM 1890 C VAL A 260 68.729 64.842 24.981 1.00 65.26 C ATOM 1891 O VAL A 260 69.055 66.028 25.066 1.00 67.66 O ATOM 1892 CB VAL A 260 67.887 63.659 27.057 1.00 63.07 C ATOM 1893 CG1 VAL A 260 68.982 64.379 27.829 1.00 62.63 C ATOM 1894 CG2 VAL A 260 66.646 63.487 27.946 1.00 60.44 C ATOM 1895 N ASP A 261 69.379 64.006 24.192 1.00 64.23 N ATOM 1896 CA ASP A 261 70.510 64.414 23.369 1.00 64.63 C ATOM 1897 C ASP A 261 70.102 65.489 22.358 1.00 66.18 C ATOM 1898 O ASP A 261 70.937 66.321 21.984 1.00 64.61 O ATOM 1899 CB ASP A 261 71.162 63.222 22.698 1.00 60.02 C ATOM 1900 CG ASP A 261 71.945 63.542 21.435 1.00 60.55 C ATOM 1901 OD1 ASP A 261 73.193 63.490 21.415 1.00 58.41 O ATOM 1902 OD2 ASP A 261 71.297 63.840 20.399 1.00 59.68 O ATOM 1903 N GLY A 262 68.873 65.483 21.844 1.00 62.86 N ATOM 1904 CA GLY A 262 68.458 66.556 20.931 1.00 58.75 C ATOM 1905 C GLY A 262 68.628 66.259 19.464 1.00 53.41 C ATOM 1906 O GLY A 262 68.146 67.037 18.625 1.00 51.21 O ATOM 1907 N GLU A 263 69.195 65.086 19.073 1.00 49.11 N ATOM 1908 CA GLU A 263 69.261 64.842 17.599 1.00 49.98 C ATOM 1909 C GLU A 263 67.932 64.919 16.887 1.00 51.19 C ATOM 1910 O GLU A 263 67.757 65.537 15.804 1.00 47.11 O ATOM 1911 CB GLU A 263 69.986 63.523 17.350 1.00 50.65 C ATOM 1912 CG GLU A 263 70.171 63.210 15.852 1.00 58.42 C ATOM 1913 CD GLU A 263 71.270 64.071 15.224 1.00 58.27 C ATOM 1914 OE1 GLU A 263 72.115 64.599 15.983 1.00 58.58 O ATOM 1915 OE2 GLU A 263 71.318 64.176 13.978 1.00 50.87 O ATOM 1916 N PRO A 264 66.873 64.243 17.371 1.00 51.10 N ATOM 1917 CA PRO A 264 65.593 64.231 16.667 1.00 53.13 C ATOM 1918 C PRO A 264 65.065 65.651 16.449 1.00 56.26 C ATOM 1919 O PRO A 264 64.525 65.962 15.389 1.00 59.00 O ATOM 1920 CB PRO A 264 64.673 63.396 17.543 1.00 50.48 C ATOM 1921 CG PRO A 264 65.412 63.120 18.804 1.00 50.33 C ATOM 1922 CD PRO A 264 66.873 63.324 18.515 1.00 49.59 C ATOM 1923 N LEU A 265 65.116 66.499 17.472 1.00 57.25 N ATOM 1924 CA LEU A 265 64.721 67.896 17.402 1.00 65.00 C ATOM 1925 C LEU A 265 65.376 68.600 16.205 1.00 63.47 C ATOM 1926 O LEU A 265 64.640 69.118 15.373 1.00 65.06 O ATOM 1927 CB LEU A 265 65.092 68.648 18.682 1.00 65.66 C ATOM 1928 CG LEU A 265 64.513 68.185 19.999 1.00 67.96 C ATOM 1929 CD1 LEU A 265 65.043 69.005 21.154 1.00 70.33 C ATOM 1930 CD2 LEU A 265 63.018 68.039 19.960 1.00 67.44 C ATOM 1931 N LYS A 266 66.703 68.552 16.134 1.00 66.15 N ATOM 1932 CA LYS A 266 67.389 69.085 14.954 1.00 71.95 C ATOM 1933 C LYS A 266 66.794 68.477 13.678 1.00 77.26 C ATOM 1934 O LYS A 266 66.031 69.158 12.974 1.00 73.75 O ATOM 1935 CB LYS A 266 68.890 68.860 15.044 1.00 74.05 C ATOM 1936 CG LYS A 266 69.632 69.195 13.756 1.00 84.93 C ATOM 1937 CD LYS A 266 71.152 69.102 13.925 1.00 89.11 C ATOM 1938 CE LYS A 266 71.810 69.182 12.544 1.00 94.10 C ATOM 1939 NZ LYS A 266 73.295 69.282 12.640 1.00 98.20 N ATOM 1940 N ARG A 267 66.903 67.163 13.459 1.00 74.50 N ATOM 1941 CA ARG A 267 66.392 66.532 12.238 1.00 69.62 C ATOM 1942 C ARG A 267 64.924 66.774 11.965 1.00 70.73 C ATOM 1943 O ARG A 267 64.518 66.888 10.796 1.00 69.90 O ATOM 1944 CB ARG A 267 66.708 65.028 12.199 1.00 58.46 C ATOM 1945 CG ARG A 267 68.186 64.744 11.987 1.00 54.37 C ATOM 1946 CD ARG A 267 68.560 63.332 12.409 1.00 51.76 C ATOM 1947 NE ARG A 267 69.947 63.007 12.207 1.00 45.72 N ATOM 1948 CZ ARG A 267 70.541 62.485 11.165 1.00 42.83 C ATOM 1949 NH1 ARG A 267 69.858 62.126 10.083 1.00 45.03 N ATOM 1950 NH2 ARG A 267 71.830 62.252 11.192 1.00 37.93 N ATOM 1951 N PHE A 268 64.090 66.864 12.995 1.00 75.12 N ATOM 1952 CA PHE A 268 62.676 67.178 12.860 1.00 86.89 C ATOM 1953 C PHE A 268 62.500 68.615 12.331 1.00 92.91 C ATOM 1954 O PHE A 268 61.404 68.972 11.887 1.00 94.23 O ATOM 1955 CB PHE A 268 61.919 67.052 14.169 1.00 85.79 C ATOM 1956 CG PHE A 268 61.405 65.736 14.632 1.00 87.53 C ATOM 1957 CD1 PHE A 268 60.289 65.704 15.469 1.00 87.65 C ATOM 1958 CD2 PHE A 268 61.978 64.522 14.286 1.00 87.93 C ATOM 1959 CE1 PHE A 268 59.771 64.504 15.925 1.00 89.32 C ATOM 1960 CE2 PHE A 268 61.472 63.325 14.748 1.00 87.15 C ATOM 1961 CZ PHE A 268 60.362 63.306 15.571 1.00 87.10 C ATOM 1962 N ARG A 269 63.513 69.448 12.492 1.00 99.67 N ATOM 1963 CA ARG A 269 63.630 70.766 11.874 1.00106.68 C ATOM 1964 C ARG A 269 64.280 70.538 10.500 1.00109.14 C ATOM 1965 O ARG A 269 65.503 70.587 10.369 1.00109.79 O ATOM 1966 CB ARG A 269 64.493 71.675 12.759 1.00110.87 C ATOM 1967 CG ARG A 269 65.035 72.945 12.151 1.00116.08 C ATOM 1968 CD ARG A 269 66.283 73.467 12.859 1.00120.19 C ATOM 1969 NE ARG A 269 66.590 74.831 12.449 1.00123.80 N ATOM 1970 CZ ARG A 269 67.650 75.571 12.708 1.00123.73 C ATOM 1971 NH1 ARG A 269 68.658 75.107 13.431 1.00123.47 N ATOM 1972 NH2 ARG A 269 67.715 76.816 12.228 1.00124.70 N ATOM 1973 N GLN A 270 63.528 69.987 9.564 1.00114.62 N ATOM 1974 CA GLN A 270 63.975 69.606 8.236 1.00116.71 C ATOM 1975 C GLN A 270 62.785 68.940 7.505 1.00116.18 C ATOM 1976 O GLN A 270 61.710 68.872 8.153 1.00116.22 O ATOM 1977 CB GLN A 270 65.165 68.680 8.217 1.00119.74 C ATOM 1978 CG GLN A 270 66.567 69.176 8.100 1.00124.39 C ATOM 1979 CD GLN A 270 66.773 70.617 7.703 1.00127.97 C ATOM 1980 OE1 GLN A 270 66.219 71.120 6.719 1.00127.49 O ATOM 1981 NE2 GLN A 270 67.586 71.317 8.514 1.00129.66 N TER 1982 GLN A 270 END