Enzyme - EC 6.4.1.2 - acetyl-CoA carboxylase
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EC
6.4.1.2
Official Name
acetyl-CoA carboxylase
Alternative Name(s)
--
Class
6.Ligases
4.Forming carbon-carbon bonds
4.Forming carbon-carbon bonds
Catalysed reaction
ATP + acetyl-CoA + HCO3- 
ADP
+ P + malonyl-CoA
ADP
+ P + malonyl-CoASubstrates
ATP
acetyl-CoA
Propanoyl-CoA
Butanoyl-CoA
HCO3-
acetyl-CoA
Propanoyl-CoA
Butanoyl-CoA
HCO3-
Products
ortho-P
Malonyl-CoA
Inhibitor(s)
RS)-2-[4-(3-Chloro-5-(trifluoromethyl-2-pyridyloxy)phenoxy]-propionic acid
Cofactor(s)
Biotin
Metabolic Pathways
Other comments
Also catalyzes transcarboxylation; the plant enzyme also carboxylates propanoyl-CoA and butanoyl-CoA.
Contains a carbamoyl-P sintase domain.