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Enzyme - EC 6.3.3.1 - Phosphoribosylformylglycinamidine cyclo-ligase
Click on the image to start downloading the PDB file (tridimensional and interactive).
EC
6.3.3.1
Official Name
Phosphoribosylformylglycinamidine cyclo-ligase
Alternative Name(s)
Phosphoribosyl-aminoimidazole synthetase
Phosphoribosylaminoimidazole synthetase
AIR synthase.
AIR synthetase
AIRS
Class
6.Ligases
3.Forming carbon-nitrogen bonds
3.Cyclo-ligases
Catalysed reaction
ATP + 2-(formamido)-N1-(5-P-D-ribosyl)acetamidine
ADP + P + 5-amino-1-(5-P-D-ribosyl)imidazole
Substrates
ATP
2-(Formamido)-N1-(5'-P-ribosyl)acetamidine
Products
ADP
ortho-P
1-(5'-P-ribosyl)-5-aminoimidazole
Metabolic Pathways
Purine ribonucleotides synthesis
(
3D
)
Expasy Molecular Information Server
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