Enzyme - EC 4.1.3.27 - Anthranilate synthase

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EC
  
4.1.3.27
Official Name
Anthranilate synthase
Alternative Name(s)
--
Class
4.Lyases
1.Carbon-carbon lyases
3.Oxo-acid-lyases
Catalysed reaction
Chorismate + L-glutamine anthranilate + pyruvate + L-glutamate
Substrates
Chorismate
L-glutamine
NH3
Products
 anthranilate
pyruvate
L-glutamate
Metabolic Pathways
Synthesis of tryptophan (3D)
Other comments

In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan. The native enzyme in the complex with uses either glutamine or (less efficiently) NH3. The enzyme separated from the complex uses NH3 only.

Glutamine amidotransferase activity.

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