Enzyme - EC 2.7.1.6 - Galactokinase
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The tridimensional structure of this enzyme has not been resolved yet. |
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EC
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2.7.1.6
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Official Name
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Galactokinase
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Alternative Name(s)
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--
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Class
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2.Transferases 7.Transferring phosphorus-containing groups 1.Phosphotransferases with an alcohol group as acceptor |
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Catalysed reaction
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ATP + D-galactose ADP
+ D-galactose 1-P
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Substrates
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ATP
D-galactose D-galactosamine |
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Products
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ADP
D-galactose-1-P D-galactosamine-1-P |
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Metabolic Pathways
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Other comments
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D-galactosamine can also act as acceptor. |
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There are three well conserved regions in the sequence of eukaryotic and prokaryotic galactokinase. As a signature pattern it has been selected the best conserved of these regions, which is located in the N-terminal section of galactokinase. |
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In yeast the GAL3 protein is required for rapid induction of the galactose
system. The exact function of GAL3 is not known, but it may be involved in the
production of a true inducer or coinducer molecule. The sequence of GAL3 is
closely related to that of galactokinases. |
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