Enzyme - EC 2.7.1.6 - Galactokinase
 

The tridimensional structure of this enzyme has not been resolved yet.


EC
 
2.7.1.6
Official Name
 
Galactokinase
Alternative Name(s)
 
--
Class
 
2.Transferases
7.Transferring phosphorus-containing groups
1.Phosphotransferases with an alcohol group as acceptor
Catalysed reaction
 
ATP + D-galactose ADP + D-galactose 1-P
Substrates
 
ATP
D-galactose
D-galactosamine
Products
 
ADP
D-galactose-1-P
D-galactosamine-1-P
Metabolic Pathways
 
Other comments
 

D-galactosamine can also act as acceptor.

GMHP kinase.

There are three well conserved regions in the sequence of eukaryotic and prokaryotic galactokinase. As a signature pattern it has been selected the best conserved of these regions, which is located in the N-terminal section of galactokinase.

In yeast the GAL3 protein is required for rapid induction of the galactose system. The exact function of GAL3 is not known, but it may be involved in the production of a true inducer or coinducer molecule. The sequence of GAL3 is closely related to that of galactokinases.
Reference


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