Enzyme - EC 2.4.2.17 - ATP phosphoribosyltransferase
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The tridimensional structure of this enzyme has not been resolved yet.
EC
2.4.2.17
Official Name
ATP phosphoribosyltransferase
Alternative Name(s)
Phosphoribosyl-ATP pyrophosphorylase.
Phosphoribosyl-ATP diphosphorylase
Phosphoribosyl-ATP diphosphorylase
Class
2.Transferases
4.Glycosyltransferases
2.Pentosyltransferases
4.Glycosyltransferases
2.Pentosyltransferases
Catalysed reaction
1-(5-phospho-D-ribosyl)-ATP + di-P 
ATP
+ 5-phospho-a-D-ribose 1-di-P
ATP
+ 5-phospho-a-D-ribose 1-di-PSubstrates
N1-(5-phospho-D-ribosyl)-ATP
Pirophosphate
Pirophosphate
Products
ATP
5-phospho-a-D-ribose 1-di-P
5-phospho-a-D-ribose 1-di-P
Metabolic Pathways
Other comments
ATP phosphoribosyltransferase is the enzyme that catalyzes the
first step in the biosynthesis of histidine in bacteria, fungi and plants. It
is a protein of about 23 to 32 Kd. As a signature pattern we selected a region
located in the C-terminal part of this enzyme.
Reference