Enzyme - EC 2.4.2.10 - Orotate phosphoribosyltransferase
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EC
2.4.2.10
Official Name
Orotate phosphoribosyltransferase
Alternative Name(s)
Orotidylic acid phosphorylase
Orotidine-5'-phosphate pyrophosphorylase
Orotidine-5'-phosphate diphosphorylase
OPRT
Orotidine-5'-phosphate pyrophosphorylase
Orotidine-5'-phosphate diphosphorylase
OPRT
Class
2.Transferases
4.Glycosyltransferases
2.Pentosyltransferases
4.Glycosyltransferases
2.Pentosyltransferases
Catalysed reaction
Orotidine 5'-P + di-P 
orotate
+ 5-phospho-a-D-ribose 1-di-P
orotate
+ 5-phospho-a-D-ribose 1-di-PSubstrates
Orotidine 5'-P
PP
PP
Products
Orotate
5-P-a-D-ribose 1-di-P
UMP
CO2
5-P-a-D-ribose 1-di-P
UMP
CO2
Metabolic Pathways
Other comments
The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23.
Belongs to the phosphoribosyltransferases group.