Enzyme - EC
2.1.1.14 - 5-methyltetrahydropteroyltriglutamate homocysteine S-methyltransferase
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The tridimensional structure of this enzyme has not been resolved yet.
EC
2.1.1.14
Official
Name
5-methyltetrahydropteroyltriglutamate homocysteine S-methyltransferase
Alternative
name(s)
Methionine synthase
Tetrahydropteroyltriglutamate methyltransferase.
Tetrahydropteroyltriglutamate methyltransferase.
Class
2.Transferases
1.Transferring one-carbon groups
1.Methyltransferases
1.Transferring one-carbon groups
1.Methyltransferases
Reaction
catalysed
5-methyltetrahydropteroyltri-L-glutamate
+ L-homocysteine 
tetrahydropteroyltri-L-glutamate
+ L-methionine
tetrahydropteroyltri-L-glutamate
+ L-methionineSubstrates
5-methyltetrahydropteroyltri-L-glutamate
L-homocysteine
L-homocysteine
Products
tetrahydropteroyltri-L-glutamate
L-methionine
L-methionine
Cofactor
phosphate
Metabolic
Pathways
Other
comments
Requires phosphate. The enzyme from Escherichia coli also requires a reducing system.