Enzyme - EC 1.3.99.11 - Dihydroorotate dehydrogenase
 
The tridimensional structure of this enzyme has not been resolved yet.

EC
 
1.3.99.11
Official Name
 
Dihydroorotate dehydrogenase
Alternative name(s)
 
--
Class
 
1.Oxidoreductases
3.Acting on the CH-CH group of donors
99.With other acceptors
Reaction catalysed
 
(S)-Dihydroorotate + acceptor orotate + reduced acceptor
Substrates
 
(S)-Dihydroorotate
acceptor
O2
2,6-Dichloroindophenol
1,10-Phenanthroline
Products
 
orotate
reduced acceptor
H2O
2,6-Dichlorophenol-4-(p-benzoquinone imine)

Cofactors

 
Iron; Zinc
Metabolic Pathways
 
Other comments
 

An iron-zinc protein. Oxygen can act as acceptor, but much more slowly than 2,6-dichloroindophenol or 1,10-phenanthroline.


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