Enzyme - EC
1.3.1.12 - Prephenate dehydrogenase
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The tridimensional structure
of this enzyme has not been resolved yet.
EC
1.3.1.12
Official
Name
Prephenate dehydrogenase
Alternative
name(s)
Hydroxyphenylpyruvate synthase
Class
1.Oxidoreductases
3.Acting on the CH-CH group of donors
1.With NAD+ or NADP+ as acceptor
3.Acting on the CH-CH group of donors
1.With NAD+ or NADP+ as acceptor
Reaction
catalysed
Prephenate + NAD+
4-hydroxyphenylpyruvate
+ CO2 + NADH
4-hydroxyphenylpyruvate
+ CO2 + NADHSubstrates
Prephenate
NAD+
NAD+
Products
3-(4-hydroxyphenyl)pyruvate
CO2
NADH
CO2
NADH
Metabolic Pathways
Other
comments
This enzyme in the enteric bacteria also possesses chorismate mutase activity (EC 5.4.99.5) and converts chorismate into prephenate.